Abbott Laboratories · NYSE:ABT
Abbott Laboratories — Investor Presentation (May 2022)
30 slides from Abbott Laboratories's investor presentation, May 2022
Slide 1: Masterclass 2: Behavioral frameworks for understanding patient adherence
MASTERCLASS 2 Réfléchir à une autre photo et mise en page Behavioral frameworks for understanding patient adherence Prof. John Weinman King’s College London Proprietary and confidential : Do not distribute GLO2138674. July GLO2138674-3. GLO2138674-3. 2020 May May 2022|| 2022 1
Slide 2: Overview
Behavioral frameworks for understanding patient adherence Overview 01 03 Current state. of knowledge re. Background – Adherence is a behavior determinants 02 04 Going beyond knowledge & forgetting: Implications for changing adherence the importance of beliefs behavior Proprietary and confidential :
Slide 3: Adherence is a behavior
Adherence is a behavior Adherence = The extent to which patients follow medical treatment and advice (i) Uptake1 (ii) Implementation1 (iii) Discontinuation1 1. Bernard Vrijens , Sabina De Geest, Dyfrig A. Hughes, Kardas Przemyslaw, Jenny Demonceau, Todd Ruppar, Fabienne Dobbels, Emily Fargher, Valer
Slide 4: Adherence is a behavior: Early explanations
Adherence is a behavior Early explanations Early explanations of non- Early interventions – mainly based BUT - information provision per se adherence – (A) lack of knowledge on information provision and/or doesn’t change behavior. or understanding2 ; (B) forgetting.2 reminders. We all know lots of i
Slide 5: Adherence is a behavior: Forgetting
Adherence is a behavior Forgetting Many patients state forgetting as their main reason for non-adherence (roughly 25% of patients3) BUT - providing reminders only helpful if people are motivated to adhere. Large recent studies have shown that reminders don’t work for people Is it just forgetting? Ma
Slide 6: Overview
Behavioral frameworks for understanding patient adherence Overview 01 03 Current state. of knowledge re. Background – Adherence is a behavior determinants 02 04 Going beyond knowledge & forgetting: Implications for changing adherence the importance of beliefs behavior Proprietary and confidential :
Slide 7: Going beyond knowledge & forgetting
Going beyond Health Belief Model knowledge & forgetting (health threat beliefs) The importance of beliefs When it was realized that information Necessity/Concerns Theory of Planned framework behavior provision did not (treatment beliefs) (behavioral beliefs) change health related BELIEFS behavior, o
Slide 8: Going beyond knowledge & forgetting: Health Belief Model
Going beyond knowledge & forgetting The importance of beliefs Health behavior (including adherence) – based A general model which has been applied to many on two factors health behaviors, particularly preventive The Health behaviors but has been applied to adherence • Threat perceptions (severity x
Slide 9: Theory of planned behavior
Going beyond knowledge & forgetting The importance of beliefs A general theory aimed at explaining Proposes that the key INTENTION assumed to be how beliefs /attitudes influence determinants of a behavior determined by 3 factors: Theory of a person’ decision to engage in a (eg adherence) are: • Atti
Slide 10: Social Cognitive theory
Going beyond knowledge & forgetting: importance of beliefs Social Cognitive theory7 Proposes that behavior (including adherence) is determined by 3 main factors Goals – plans to act Outcome expectancies – Self-efficacy – beliefs about how much the behavior is ( similar to intentions) beliefs about t
Slide 11: Illness beliefs (Leventhal's Common-Sense Model)
Going beyond knowledge & forgetting The importance of beliefs Illness beliefs (Leventhal’s Common-Sense Model of self-regulation8) Patients develop their own beliefs about the nature of their illness, symptom or health threat. Patients’ illness beliefs directly influence their coping, including adhe
Slide 12: Leventhal's self-regulation model
Leventhal’s self-regulation model9 If-then rules ‘Illness’ Coping Appraisal Representation Procedure Stimulus Health Threat Emotional Coping Appraisal Response Procedure 9. Self-Regulation, Health Psychology, [Accessed 26 June 2020], http://psychology.iresearchnet.com/health-psychology-research/self
Slide 13: Core beliefs about illness (Leventhal SRM)
Core beliefs about illness (Leventhal SRM9) Belief Category Description Abstract label e.g., hypertension; asthma; arthritis Identity Concrete symptoms that a person associates with the condition Causal Beliefs Stress, environment, genetics, own behavior, ageing, etc. Timeline Perceived duration and
Slide 14: Illness perception & treatment adherence
Illness perception & treatment adherence Some illness perceptions are associated with treatment adherence in some conditions, E.G. Causal beliefs predict Timeline beliefs predict Causal, timeline & control adherence behavior preventer medication adherence beliefs predict adherence to in post- MI10 i
Slide 15: Beliefs about medicines questionnaire
Beliefs about medicines questionnaire13 Specific Beliefs about medicines prescribed for a particular illness General Beliefs about medicines as a whole 13. Robert Horne, John Weinman and Maittew Hankins: The beliefs about medicines questionnaire: The development and evaluation of a new method for as
Slide 16: Beliefs about medicines questionnaire: Specific beliefs
Beliefs about medicines questionnaire14 Specific Beliefs Views about prescribed medication Necessity Concerns Beliefs about necessity of prescribed Arising from beliefs about medication for maintaining health potential negative effects 14. Robert Horne, John Weinman and Maittew Hankins: The beliefs
Slide 17: Studies in asthma, CHD, cancer, renal dialysis, HIV/AIDS, hypertension, diabetes
Studies in asthma, CHD, cancer, renal dialysis, HIV/AIDS, hypertension, diabetes15 Doubts about Necessity Low adherence Concerns about potential adverse effects 15. Robert Horne, Sarah C E Chapman, Rhian Parham, Nick Freemantle, Alastair Forbes and Vanessa Cooper: Understanding Patients’ Adherence-R
Slide 18: Overview
Behavioral frameworks for understanding patient adherence Overview 01 03 Current state of knowledge re. Background – Adherence is a behavior determinants 02 04 Going beyond knowledge & forgetting: Implications for changing adherence the importance of beliefs behavior Proprietary and confidential : D
Slide 19: Current state of knowledge re. determinants
Current state of knowledge re. determinants Which are the most important for adherence? Systematic reviews – reveal very large number of possible causal factors of non-adherence16 Modifiable (e.g. knowledge, motivation, support) & non-modifiable factors (e.g. age, gender, SES) 16. Przemyslaw Kardas,
Slide 20: Predictors of non-adherence: overview of evidence
Predictors of non-adherence: overview of evidence17 Weak Evidence Moderate Evidence Strong Evidence • Gender • Cognitive ability, depression, social support, • Concerns about treatment • Income coping skills (fear of side effects, etc.) • Age • Number of medicines, disease seriousness • Beliefs abou
Slide 21: Current state of knowledge: the COM-B framework
Current state of knowledge re. determinants • How to classify the modifiable factors : the COM-B framework 18 Capability • Incorporates all the factors which have been found to influence health-related behaviors, and puts then into 3 broad groups − Capability Motivation B=Behavior − Opportunity − Mo
Slide 22: A new approach to classifying causes of non-adherence: COM-B
A new approach to classifying causes of non-adherence: COM-B19 CAPABILITY MOTIVATION OPPORTUNITY Physical Reflective Social e.g. dexterity, e.g. beliefs about e.g. HCP swallowing illness, treatment communication, social support Psychological Automatic e.g. memory, e.g. emotions; Physical knowledge,
Slide 23: Applying COM-B framework to medication adherence in hypertension
Applying com-b framework to medication adherence in hypertension Capability Motivation Opportunity • Poor knowledge of • Beliefs about • Complexity of regimen hypertension hypertension in patients with • Poor understanding of • Low beliefs in need for comorbid conditions risk Problems in treatment •
Slide 24: COM-B factors for dyslipidemia patients
Factors impacting capability, opportunity and motivation of dyslipidemia patients to adhere and self-manage The COM-B model helps to explain the reasons why someone may engage in a particular behavior, by dividing them into 3 components that interact with each other Motivation Low perceived risk of
Slide 25: COM-B factors for vertigo patients
Factors impacting capability, opportunity and motivation of vertigo patients to self-manage The COM-B model helps to explain the reasons why someone may engage in a particular behavior, by dividing them into 3 components that interact with each other23 Opportunity Motivation Availability of medicati
Slide 26: Overview
Behavioral frameworks for understanding patient adherence Overview 01 03 Current state. of knowledge re. Background – Adherence is a behavior determinants 02 04 Going beyond knowledge & forgetting: Implications for changing adherence the importance of beliefs behavior Proprietary and confidential :
Slide 27: Implications for changing adherence behavior
Implications for changing adherence behavior Importance of Need to find out Address understanding individual these with drivers/barriers for drivers/barriers for appropriate each patient over time each patient (C, O or M?) intervention24 24. Samuel S. Allemann, Robby Nieuwlaat, Bart J.F. van den Bem
Slide 28: Using the consultation to facilitate informed adherence
Using the consultation to facilitate informed adherence Check patient’s understanding of treatment and, if necessary: Provide clear rationale for necessity of treatment Elicit and address concerns Agree practical plan for how, where and when to take treatment Identify any possible barriers Proprieta
Slide 29: Disclaimer
Disclaimer This presentation is offered for educational purposes only, intended to serve as continuing medical education for health care professionals. The content of the presentation represents the views and opinions of the original creators of such content and does not necessarily represent the vi
Slide 30: Proprietary and confidential : Do not distribute GLO2138674. July
Proprietary and confidential : Do not distribute GLO2138674. July GLO2138674-3. 2020 May 2022|| 30
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