Slide 1: Benefits of using FreeStyle Libre with GLP-1 therapy
Benefits of using FreeStyle Libre with GLP-1 therapy November 2023
Slide 2: Overview and Conclusions
Overview and Conclusions Overview: • Conducted a large, real-world study to evaluate whether adding FreeStyle Libre to GLP-1 therapy further improves HbA1c • Study included people with Type 2 diabetes who were already using a GLP-1 and had an elevated HbA1c level (≥ 8%) at the time they first starte
Slide 3: Study Design
Study Design Data Source: • Optum’s de-identified Market Clarity Data, a linked electronic health records (EHR)-claims database Inclusion criteria: • Adults (18+ years of age) • Type 2 diabetes diagnosis between 2018-2022 • Elevated HbA1c (≥ 8%) at the time of starting to use FreeStyle Libre • Activ
Slide 4: Overall Results
Overall Results Patients who were already using a GLP-1 saw a significant (p<0.001) improvement in HbA1c after adding FreeStyle Libre 10 -1.5 9.8 9 HbA1c (%) 8.3 8 07 GLP-1 Only GLP-1 and FreeStyle Libre Gray bar represents baseline HbA1c measurement just before adding Libre Blue bar represents foll
Slide 5: Time Gap Between Starting GLP-1 and Adding FreeStyle Libre
Results: By Time Gap Between Starting GLP-1 and Adding FreeStyle Libre Regardless of the time gap between starting GLP-1 therapy and adding FreeStyle Libre, a significant (p<0.001) benefit was seen by adding FreeStyle Libre to the treatment regimen -2.3 10 10.2 -1.2 -1.2 -1.3 9.7 9.7 9.7 HbA1c (%) 9
Slide 6: GLP-1 Product Type
Results: By GLP-1 Product Type Regardless of the GLP-1 product used, patients significantly (p<0.001) benefited from adding FreeStyle Libre 10 -1.8 -1.5 -1.3 9.9 9.8 9.7 9 HbA1c (%) 8.5 8.3 8 8.1 07 Semaglutide Dulaglutide Other GLP-1s GLP-1 Only GLP-1 and FreeStyle Libre Common brand names: Gray ba
Slide 7: User Type
Results: By User Type Both insulin users and non-insulin users significantly (p<0.001) benefited from adding FreeStyle Libre 10 -1.3 -1.4 -1.8 9.9 9.9 9.7 9 HbA1c (%) 8.6 8.5 8 7.9 07 MDI Insulin Users Basal Insulin Users No Insulin Use GLP-1 Only GLP-1 and FreeStyle Libre Gray bars represent baseli
Slide 8: Patient Characteristics
Patient Characteristics N=1,781 adults with Type 2 diabetes who were on GLP-1 therapy and then added FreeStyle Libre Patient Characteristics Age (years) 55 ± 10 Male 930 (52%) Female 851 (48%) Race: African American 286 (16%) Asian 35 (2%) Caucasian 1,279 (72%) Other/unknown 181 (10%) Insulin Use: M