Orion Oyj Class A · OMXHEX:ORNAV

Orion Oyj Class A — Q1 2025 Earnings Presentation

16 slides from Orion Oyj Class A's earnings presentation, Apr 23, 2025

  1. Slide 1: Orion Interim Report January-March 2025

    Orion Interim Report January-March 2025 23 April 2025

  2. Slide 2: Disclaimer

    Disclaimer This presentation contains forward-looking statements which involve risks and uncertainty factors. These statements are not based on historical facts but relate to the Company’s future activities and performance. They include statements about future strategies and anticipated benefits of

  3. Slide 3: Q1 2025 Highlights

    Q1 2025 Highlights • Solid growth in four out of five business divisions • Orion to open new Biologics R&D Centre in Cambridge, UK in 2025 • Phase III trial with levosimendan by Tenax Therapeutics, Inc. added to Orion’s Key clinical development pipeline 3 23 April 2025 © Orion Corporation

  4. Slide 4: Q1 2025 Financial highlights

    Q1 2025 Financial highlights Net sales, EUR million Operating profit, EUR million Operating cash flow per share, EUR Operating profit margin 22.0% (18.2%) +14.9% +39.1% -29.7% 354.6 77.9 0.78 308.5 56.0 0.55 Q1/2024 Q1/2025 Q1/2024 Q1/2025 Q1/2024 Q1/2025 4 23 April 2025 © Orion Corporation

  5. Slide 5: Net sales bridge (MEUR)

    Net sales bridge (MEUR) 3.3 -5.1 6.8 -0.4 354.6 1.0 308.5 40.4 Q1/2024 1 2 3 4 5 6 Q1/2025 1 Innovative Medicines 4 Animal Health 2 Branded Products 5 Fermion 3 Generics and Consumer Health 6 Translation differences and Other operations 5 23 April 2025 © Orion Corporation The figures in the chart ar

  6. Slide 6: Operating profit bridge (MEUR)

    Operating profit bridge (MEUR) -1.1 0.3 -9.7 77.9 21.8 -5.6 2.5 13.7 56.0 Q1/2024 1 2 3 4 5 6 7 Q1/2025 1 Change in sales volume 5 Milestones 2 Changes in prices, cost and product mix 6 Other operating income and expenses 3 Exchange rate effect on gross margin 7 Fixed cost 4 Royalties 6 23 April 202

  7. Slide 7: Innovative Medicines

    Innovative Medicines +70.4% Nubeqa® sales (MEUR) 97.8 152 6.3 • Both Nubeqa® royalties and 36 product sales showed very strong growth 95 92 57.4 7.9 72 26 91.5 62 38 50 21 116 45 22 37 18 49.5 16 69 11 MEUR 51 54 41 32 29 27 Q1/2024 Q1/2025 2023 2023 2023 2024 2024 2024 2024 2025 Q2 Q3 Q4 Q1 Q2 Q3 Q

  8. Slide 8: Branded Products

    Branded Products +9.7% 77.0 Sales split • Easyhaler® product portfolio 70.2 7.2 (+8.1%) continued strong growth 5.5 9% with budesonide-formoterol combination product (+14.9%) as 23.4 22.1 a driver • CNS sales grew by 5.7% mainly 30% due to entacapone sales in Japan 60% 42.6 46.5 MEUR Q1/2024 Q1/2025

  9. Slide 9: Generics and Consumer Health

    Generics and Consumer Health +0.7% Sales split by geographic areas • Good availability of Orion 130.7 131.7 products in Scandinavia supported growth 11% 33.8 33.3 10% MEUR 20% 60% 96.8 98.4 Q1/2024 Q1/2025 Generic prescription drugs Finland and Baltics Eastern Europe Self-care products Scandinavia R

  10. Slide 10: Animal Health and Fermion

    Animal Health and Fermion Animal Health Fermion • Nice growth for Animal Health even with strong comparison +10.4% period 35.2 • Sales of the animal sedatives 31.9 8.8 product group decreased from 10.3 the comparison period, but were at a good level -27.3% 18.5 • Fermion’s capacity allocated more 26

  11. Slide 11: TOP 10 products and total sales split by division

    TOP 10 products and total sales split by division EUR vs. Product or product portfolio million Q1/2024 1. Nubeqa® 91.5 +84.9% 4% 10% 2. Easyhaler® product portfolio 45.1 +8.1% 28% 3. Entacapone products1 21.2 +6.0% 4. Dexdomitor®, Domitor®, Domosedan®, Antisedan® 8.8 -14.1% 5. Divina® series 7.2 +30

  12. Slide 12: Key clinical development pipeline

    Key clinical development pipeline Partner Project/compound Indication PHASE I PHASE II PHASE III REGISTRATION ARANOTE / darolutamide Prostate cancer (mHSPC) ARASTEP / darolutamide Prostate cancer (BCR) OMAHA1 / opevesostat Prostate cancer (mCRPC) OMAHA2a / opevesostat Prostate cancer (mCRPC) CYPIDES

  13. Slide 13: Some sustainability highlights from 2024

    Some sustainability highlights from 2024 • Orion’s first CSRD report was published in March as part of the Report by the Board of Directors • More highlights from 2024 at: https://www.orionpharma.com/investors/orion-highlights-2024/ 13 23 April 2025 © Orion Corporation

  14. Slide 14: Outlook for 2025

    Outlook for 2025 Net sales EUR 1,550–1,650 million Operating profit EUR 350–450 million 14 23 April 2025 © Orion Corporation

  15. Slide 15: Capital Markets Day in Helsinki on 22 May 2025

    Capital Markets Day in Helsinki on 22 May 2025 15 23 April 2025 © Orion Corporation

  16. Slide 16: Upcoming events

    Upcoming events Capital Markets Day 22/5/2025 Half-Year Financial Report 1–6/2025 18/7/2025 Interim Report 1–9/2025 28/10/2025 16 23 April 2025 © Orion Corporation

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