Nurexone Biologic Inc · TSXV:NRX

Nurexone Biologic — Investor Presentation (May 2026)

17 slides from Nurexone Biologic's investor presentation, May 2026

  1. Slide 1: Where Nature Ends, NurExone Begins

    Where Nature Ends, NurExone Begins Where Nature Ends, NurExone Begins Transforming Regenerative Medicine Q4 2025 | Canada (TSXV: NRX) Germany (FRA: J90.F) US (OTCQB: NRXBF)

  2. Slide 2: Disclaimer

    DISCLAIMER DISCLAIMER Contents of this presentation are provided for general information purposes only and do not constitute an offer to sell or solicitation of an offer to buy any security in any jurisdiction. This presentation contains “forward-looking information” for purposes of applicable secur

  3. Slide 3: Reeve-Irvine Research Center quote on spinal cord regeneration

    [Christopher] Reeve-Irvine Research Center (RIRC) : [Christopher] Reeve-Irvine Research Center (RIRC) : “All scientists agree that the best way to restore function after spinal cord injury is to find ways to regenerate the [neural] connections that are broken ”1 https://www.reeve.uci.edu/research/re

  4. Slide 4: Company Overview

    COMPANY OVERVIEW SINCE ITS INCEPTION, COMPANY OVERVIEW NUREXONE HAS RAISED US$~20M Founded in 2020, NurExone trades on the TSX Venture Canada (TSXV: NRX), Germany (FRA: J90.F) US (OTCQB: NRXBF) Founders 25% Key assets: Shareholder Technology: 5 patent families 2 already granted in US and ● Ownership

  5. Slide 5: Corporate Structure

    CORPORATE STRUCTURE CORPORATE STRUCTURE 100% 100% NurExoneBiologic Inc [TSXV:”NRX”,OTCQB:”NRXBF”,GER:”J90] NurExone Biologic Ltd ExoTop – Cells & Exosomes [Israeli Private Company] [USA Private Company] • R&D • Naïve Exosome Production • Product Development • Naïve Exosome Supply • Product Productio

  6. Slide 6: Addressing Multi-Billion Dollar Global Markets with Unmet Medical Needs

    ADDRESSING MULTI-BILLION DOLLAR GLOBAL MARKETS WITH UNMET MEDICAL NEEDS ADDRESSING MULTI-BILLION DOLLAR GLOBAL MARKETS WITH UNMET MEDICAL NEEDS NurExone’s first two Central Nervous System indications 1 Acute Spinal Cord Injury (SCI) 2 Glaucoma - Acute Glaucoma “There is currently no way to repair a

  7. Slide 7: ExoPTEN: Acute Spinal Cord Injury

    ExoPTEN: Acute Spinal Cord Injury ExoPTEN: Acute Spinal Cord Injury Preclinical Data Suggests Potential to Heal Transected spinal cord (rat) 2 weeks post internasal ExoPTEN treatment Damaged Neurons and Restore Motor Function ◉ Short cycles of NurExone's regenerative ExoPTEN therapy administered int

  8. Slide 8: ExoPTEN: Acute Glaucoma

    Optic Nerve Cell Survival (Retinal Ganglion Cells) Optic Nerve Cell Survival (Retinal Ganglion Cells) ExoPTEN: ACUTE GLAUCOMA Preclinical Data Suggests Optic Nerve Healing and Vision Restoration 15 10 5 uV 0 -5 -10 A-left side-normal, B-middle-damaged, C-right side-after treatment, 0 28.5 9.5 47.5 6

  9. Slide 9: Pipeline

    Pipeline Cutting Edge ExoTherapy Development to Recover Lost Function Pipeline Cutting Edge ExoTherapy Development to Recover Lost Function A single process serving multiple high-value indications 9

  10. Slide 10: How Do We Do It? Harnessing the Regenerative Power of Exosomes

    HOW DO WE DO IT? HARNESSING THE REGENERATIVE POWER OF EXOSOMES Nature’s “Guided Missiles” Targeting Inflammation HOW DO WE DO IT? HARNESSING THE REGENERATIVE POWER OF EXOSOMES Nature’s “Guided Missiles” Targeting Inflammation ◉ Exosomes are naturally occurring nanoparticles with healing and “homing”

  11. Slide 11: Commercialization: Multi-Layered Revenue Strategy

    COMMERCIALIZATION: MULTI-LAYERED REVENUE STRATEGY Potential Revenue Streams COMMERCIALIZATION: MULTI-LAYERED REVENUE STRATEGY Potential Revenue Streams Product/Technology Main Focus: ExoPTEN for Acute Spinal Cord Injury - leading product with accelerated “time to market” strategy ExoPTEN for Optic N

  12. Slide 12: Product Road Map

    PRODUCT ROAD MAP Clear Path towards Clinical Trials PRODUCT ROAD MAP Clear Path towards Clinical Trials Plans for FDA and EMA approvals and a near term human clinical trial Q1 2023 H1 2023 Q4 2023 H1 2024 On-going 2025 H2 2026 H1 2027 Establish scaled up Finalize product ODD Approval Preclinical OMP

  13. Slide 13: Experienced Leadership Team

    EXPERIENCED LEADERSHIP TEAM EXPERIENCED LEADERSHIP TEAM Dr. Lior Shaltiel Mr. Eran Ovadya Mr. Yoram Drucker Dr. Tali Kizhner Dr. Ina Sarel Chief Executive Officer Chief Financial Officer Founder, VP Strategic R&D Director Head of CMC, & Director A professional track record from Development & Chairma

  14. Slide 14: Seasoned Board of Directors

    SEASONED BOARD OF DIRECTORS SEASONED BOARD OF DIRECTORS Israel Canada Eyal Gabbai, MBA Dr. Lior Shaltiel Yoram Drucker Oded Orgil, LL.B. James (Jay) Richardson, CPA Director Chief Executive Officer Founder, VP Business Development Director Director & Active Chairman of the Board Mr. Gabbai brings ex

  15. Slide 15: Expert Scientific Advisory Board

    EXPERT SCIENTIFIC ADVISORY BOARD EXPERT SCIENTIFIC ADVISORY BOARD Prof. Teodoro Forcht Dagi, MD, MPH Prof. Gabriel Zeilig, MD Prof. Michael Belkin, MD neurosurgeon who serves as distinguished scholar and Prof. Gabi Zeilig is the director of the Department of Prof. Belkin was the founder of the Eye R

  16. Slide 16: NurExone Biologic - Summary

    NUREXONE BIOLOGIC - SUMMARY Regenerating Nerves and Recovering Lost Function NUREXONE BIOLOGIC - SUMMARY Regenerating Nerves and Recovering Lost Function ExoTherapy platform harnesses exosomes to deliver targeted therapies for a diverse range of diseases- a promising therapeutic approach with signif

  17. Slide 17: Thank You

    TSXV: NRX | TSXV: NRX | OTCQB: NRXBF TSXV: NRX | TSXV: NRX | OTCQB: NRXBF THANK YOU For more information please contact: info@nurexone.com DISCLOSURE The matters discussed in this presentation are forward-looking statements that involve a number of risks and uncertainties. The actual future results

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