Outset Medical, Inc. · NASDAQ:OM

Outset Medical — Investor Presentation (January 2026)

18 slides from Outset Medical's investor presentation, Jan 12, 2026

  1. Slide 1: Outset Medical Investor Presentation 2026

    Outset Medical Investor Presentation 2026

  2. Slide 2: Forward-looking statements and non-GAAP information

    Forward-looking statements and non-GAAP information This presentation and the accompanying oral statements contain forward-looking statements within the meaning of the federal securities laws. All statements other than statements of historical fact are forward-looking statements. In some cases, you

  3. Slide 3: Dialysis care that improves patient outcomes with lower cost and less complexity

    Dialysis care that improves patient outcomes with lower cost and less complexity.

  4. Slide 4: Investment Highlights

    Investment Highlights ~70+% recurring revenue powered by predictable utilization Enterprise dialysis solution differentiated by expert know-how, trusted technology and exceptional service Strong cash position, capitalized through breakeven More than 1,000 sites of care performing >1,000,000 treatmen

  5. Slide 5: Dialysis is one of the largest, most expensive, least-changed sectors of healthcare

    5%2 Medicare spend for 1%2 ESRD Patients CURRENT STATE Dialysis is one of the largest, most expensive, least-changed sectors of healthcare $71B1 Annual spending on U.S. ESRD patients $55B1 Paid by Medicare 558,0001 Dialysis patients 90M1 Annual dialysis treatments 1. Company estimates based on data

  6. Slide 6: Inpatient dialysis is unreimbursed and a significant cost burden for hospitals

    CURRENT STATE NEARLY 2X higher ICU admission rate3 About 2.5X HIGHER COST per stay3 Roughly 5-DAY LONGER length-of-stay (LOS)3 $5,000–$25,000: Average loss by hospital for each inpatient stay for renal failure with dialysis2 135,000 NEW ESRD PATIENTS diagnosed annually in the U.S.1 More than 800,000

  7. Slide 7: Outsourcing the dialysis service line led to unintended consequences

    “Outsourcing” the dialysis service line became the historic standard… …leading to unintended consequences 1. Sg2, In-Hospital Dialysis Outcomes & Costs, 2025. 2. Saffer & Mesiwala, Kidney Medicine, 2023 3. Nuermaimaiti et al., Scientific Reports, 2025. 4. Lindsay & Lytle, Applied Clinical Informatic

  8. Slide 8: We see a better way forward

    We see a better way forward

  9. Slide 9: Tablo is a first-of-its-kind technology to reduce cost and complexity of dialysis

    Tablo® is a first-of-its- kind technology designed to reduce the cost and complexity of dialysis Connected and intelligent Small and mobile Single device from bedside to ICU

  10. Slide 10: A comprehensive enterprise dialysis solution

    A comprehensive enterprise dialysis solution Data Analytics & Fleet Management EMR Interoperability Implementation Services & Bridge Nursing Advanced Service & Support Tools

  11. Slide 11: Hospitals bringing dialysis in-house are transforming results

    Hospitals bringing dialysis in-house are transforming results 1. Nichols et al., Journal of Medical Economics, 2024. 2. Outset Medical, Norman Regional In-House Dialysis Case Study, 2025. 3. Cleveland Clinic, ICU Dialysis Program Case Study, 2021. 36% Reduction in ICU LOS¹ Reduction in CLABSI² COST

  12. Slide 12: Insource with Outset

    INSOURCE WITH OUTSET Experienced partner at scale >1 million treatments Annually 3+ million cumulative treatments >10,000 nurses and 1,000 physicians trained 10 of 10 LARGEST SUBACUTE PROVIDERS ~1,000 UNIQUE ACUTE SITES 8 of 8 TOP NATIONAL HEALTH SYSTEMS Extensive clinical evidence: 70+ abstracts 15

  13. Slide 13: The Home market is significantly underpenetrated

    The Home market is significantly underpenetrated EMERGING OPPORTUNITY REIMBURSEMENT Medicare reimbursement misaligned with treatment frequency Historical barriers EDUCATION Patient and physician awareness low TECHNOLOGY Cumbersome technology and training

  14. Slide 14: Tablo addresses key barriers to home dialysis adoption and retention

    Tablo addresses key barriers to home dialysis adoption and retention HOME CARE 5–6 Treatments per week 100 hours Training per patient 16–24 hours Dialysate prep time per week Historical device 3 Treatments per week <25 hours1 Training per patient 0 hours Dialysate prep time 1 Hemodialysis Internatio

  15. Slide 15: Powerful recurring revenue model

    Software Data/analytics EMR interoperability Expanded professional services Consumables Service contracts Powerful recurring revenue model ~70% of total revenue ACUTE $20,000 per console per year HOME $15,000 per console per year Growth potential

  16. Slide 16: Strong financial foundation entering 2026

    Strong financial foundation entering 2026 2025 Revenue1 $119.5M ~70% Percent of revenue from recurring sources 1 Revenue and cash figures are preliminary and unaudited. Cash position includes estimated cash, cash equivalents, restricted cash and short-term investments at Dec. 31, 2025. Figures on sl

  17. Slide 17: Outset Medica Ine Catal atic ine sua, Outset Medical, nc S ©

    Outset Medica Ine Catal atic ine sua, Outset Medical, nc 8 S © stem at Nato Park Medial C8 Os Mica developed Tablo —afst-ofit -omplexity of cialis anywhere it's delivered, for home. For the fist time a single system can deliv Outset Medical, inc. ) Hoppy #NephrologyNursesWeek f the incredible nephro

  18. Slide 18: Outset Medical

    Outset Medical 3052 Orchard Drive San Jose, CA 95134 outsetmedical.com For Important safety information, please refer to: https://www.outsetmedical.com/indications/

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