Slide 1: Continuous Reactions at Albemarle
Continuous Reactions at Albemarle 1
Slide 2: Outline
Outline • Albemarle Capability • Some Existing Continuous Reactions • Bench Scale Equipment • Multipurpose Continuous Assets 2
Slide 3: Albemarle Corporation
Albemarle Corporation 2011 Net Sales Distribution - $2.9 billion • Global provider of value Fine added technical solutions Chemistry 25% • Comprised of three business Catalysts 38% segments with balanced product portfolios • Proprietary technology and service-driven business model • Fundamentally st
Slide 4: We Offer
We Offer • US-based leading cGMP and custom manufacturing production capabilities • Full project support (Technical, Regulatory, HSE, Information Management, Logistics) • Extensive process development and scale-up capabilities • Expertise in the development of complex syntheses • Long Term Relations
Slide 5: We Have
We Have • Excellent safety record (top 10% of ACC) • Innovative technical staff that says YES! • FDA registered facilities with no 483s in last inspections • ISO certified custom manufacturing facilities • State-of-the-art analytical support • Raw material sourcing assets in China 5
Slide 6: We Have – Manufacturing Capability
We Have – Manufacturing Capability • Five Commercial Scale Multipurpose Plants • South Haven, MI (cGMP) • Orangeburg, SC (including cGMP) • Tyrone, PA • Pasadena, TX • Baton Rouge, LA 6
Slide 7: We Have – Manufacturing Capability
We Have – Manufacturing Capability • cGMP capability - kilo, pilot and commercial • 25 L to 16,000 gal Reactors of all MOCs • Distillation and Wiped Film Evaporators • Most types of solids handling • Full Utilities • Cryogenic to hot oil • Pressures to 1000 PSI • Short lead time for Environmental Pe
Slide 8: We Have – Development Capability
We Have – Development Capability Full Scale Lab Kilo Lab Pilot Plant Commercial Synthesis Plant Baton Rouge, LA Baton Rouge, LA Baton Rouge, LA Baton Rouge, LA South Haven, MI South Haven, MI South Haven, MI South Haven, MI Tyrone, PA LLN, Belgium Tyrone, PA Tyrone , PA LLN, Belgium Orangeburg, SC P
Slide 9: Albemarle Continuous Capability
Albemarle Continuous Capability • Over 40 years of Experience • World Scale Plants (100’s to >10,000’s TPY) • Existing processes at Multiple Plants • Long Term Supply • Proven Record with Recent Successes 9
Slide 10: Ag Chemical
Ag Chemical • Long Term Relationship • Expanding as Customer Grows • Started <500 TPY • Debottlenecked existing asset to > 1500 TPY • Further capacity increase with new asset • Process Includes • Hazardous Chemicals 10
Slide 11: Brominated Flame Retardant
Brominated Flame Retardant • World Scale plant • Complex process • All Unit Ops Integrated 11
Slide 12: Personal Care Intermediates
Personal Care Intermediates • Multiple Products • Tubular Plug Flow / High Pressure • Long Term Supplier 12
Slide 13: Pyrophorics
Pyrophorics • Multiple Products • Extremely Exothermic • Adiabatic Temperature Rise > 2000 °C • Unique Technical Solutions • Long Term Supplier 13
Slide 14: Custom Lubricant Production
Custom Lubricant Production • Albemarle selected as Scale up Partner • Commercial Plant Operational in 21 months • 15,000 TPY established in first month • Scale up from Lab Directly to Commercial • No Pilot Plant 14
Slide 15: Bench Scale Equipment
Bench Scale Equipment • We have a Modular Multipurpose Apparatus • Multiple Reactor Configurations • Currently up to 3 different feed streams • CSTR (single or series) • Tubular Fixedbed • Tubular Plug Flow 15
Slide 16: Bench Scale Equipment
Bench Scale Equipment • Temperature range • –100 to 200 C with circulators • higher with electric heating • Pressure range • Vacuum to 1000 PSI • >1000 PSI in High Pressure Lab • Feed rates • 1 g/min to 100 g/min 16
Slide 17: Bench Scale Equipment
Bench Scale Equipment • Computer Controlled Valves • Versatile Feed Configurations • Computer Interfaced Scales 17
Slide 18: Bench Scale Equipment
A ALBEMARLE | Fine Chemistry Services Bench Scale Equipment the yes formula 7
Slide 19: Small Pilot Scale Equipment
Small Pilot Scale Equipment Continuous Loop Type CFR Distillation Feed Pumps 19
Slide 20: Skid Mount Pilot Unit
AN ALBEMARLE | Fine Chemistry Services Skid Mount Pilot Unit the Y@S iormula ee ee IS 20
Slide 21: Multipurpose Continuous Assets
Multipurpose Continuous Assets • Existing Idle Equipment with World Scale Logistics Support (rail and ship) • Distillation Columns (100 PSI, 300 C) • Continuous Hydrogenation Columns (500 PSI) • High Pressure Reactors(1000 PSI, 300 C) 21
Slide 22: Why Choose Albemarle?
Why Choose Albemarle? • Successfully Partner with both Small and Large Companies • Leading cGMP and Custom Manufacturing Facilities • Competency in the Development of Complex Syntheses • Extensive Process Development and Scale-up Capabilities 22
Slide 23: Why Choose Albemarle?
Why Choose Albemarle? • Excellent Safety and Regulatory Record • Demonstrated Consistent Success • Large Scale Equipment Available • Long Term Partner 23
Slide 24: Find out how Albemarle says YES! to your project.
Find out how Albemarle says YES! to your project. Americas Europe, Middle East, Africa • Fine Chemistry Services • EMA Fine Chemistry Services • Tel: +1 225 388 7402 • Tel: +32 10 48 1711 • ALBSales@albemarle.com • EMASales@albemarle.com Web: www.Albemarle.com 24