Business
Seres Therapeutics Showcases SER-155 Data and Live Biotherapeutic Insights at ESCMID Global 2026
Pharmacologic data highlight durable GI microbiome modulation, with improvement in epithelial barrier integrity, following SER-155 administration Additional presentations underscore the role of live biotherapeutics in shaping outcomes in IBD and immunocompromised patients CAMBRIDGE, Mass., April 20, 2026 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (Nasdaq: MCRB) (Seres or the Company), a leading live biotherapeutics company, today announced three presentations at the 2026 European Society of Cl
About this update from Seres Therapeutics, Inc.
[{"type":"image","alt":"Seres Therapeutics, Inc.","displaySize":"","headline":null,"caption":"Seres Therapeutics, Inc.","className":"","disableSlideshowImg":false,"size":{"original":{"width":205,"height":85,"url":"https://media.zenfs.com/en/globenewswire.com/c9212fd90ce8aaab0f99113fa1623d37"},"resized":{"url":"https://s.yimg.com/ny/api/res/1.2/AevgeV1boJs7rC.lO5CETw--/YXBwaWQ9aGlnaGxhbmRlcjt3PTM2MDtoPTE0OQ--/https://media.zenfs.com/en/globenewswire.com/c9212fd90ce8aaab0f99113fa1623d37","width":205,"height":85}},"lazy":false},{"type":"text","content":"Pharmacologic data highlight durable GI microbiome modulation, with improvement in epithelial barrier integrity, following SER-155 administration","length":145,"tagName":"p"},{"type":"text","content":"Additional presentations underscore the role of live biotherapeutics in shaping outcomes in IBD and immunocompromised patients","length":126,"tagName":"p"},{"type":"text","content":"CAMBRIDGE, Mass., April 20, 2026 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (Nasdaq: MCRB) (Seres or the Company), a leading live biotherapeutics company, today announced three presentations at the 2026 European Society of Clinical Microbiology and Infectious Diseases (ESCMID) global congress, taking place April 17-21 in Munich, Germany.","length":341,"tagName":"p"},{"type":"text","content":"A poster presentation by Seres highlighted biomarker and clinical pharmacology data from the Company’s Phase 1b study of SER-155 (NCT04995653), evaluating changes in gastrointestinal (GI) microbiome composition following administration in patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT). Data showed that administration of SER-155 induced a significant and durable shift in GI microbiome composition relative to placebo, characterized by high SER-155 species relative abundance. This shift is associated with improved GI epithelial barrier integrity that could reduce the likelihood of bacterial translocation from the GI to the bloodstream. In contrast, placebo-treated participants showed low abundance of SER-155 species and related Firmicutes, high abundance of Bacteroidetes, and a compromised GI epithelial barrier. These findings are consistent with the intended mechanisms of action of SER-155, including protection of the GI epithelial barrier, and align with previously reported clinical observation of reduced incidence ...