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PharmaTher Closes Sale of Ketamine ANDA, Sharpening Focus on Long-Acting Injectable Ketamine Franchise
Toronto, Ontario--(Newsfile Corp. - December 2, 2025) - PharmaTher Holdings Ltd. (OTCQB: PHRRF) (CSE: PHRM) (the "Company" or "PharmaTher"), a specialty life sciences company focused on unlocking the therapeutic potential of ketamine for neuropsychiatric disorders, today announced it has closed the previously announced sale of its Abbreviated New Drug Application (ANDA #217858) for Ketamine Hydrochloride Injection USP to a leading sterile-injectables pharmaceutical company.At closing, PharmaTher
About this update from Pharmather Holdings Ltd
[{"type":"text","content":"Toronto, Ontario--(Newsfile Corp. - December 2, 2025) - PharmaTher Holdings Ltd. (OTCQB: PHRRF) (CSE: PHRM) (the "Company" or "PharmaTher"), a specialty life sciences company focused on unlocking the therapeutic potential of ketamine for neuropsychiatric disorders, today announced it has closed the previously announced sale of its Abbreviated New Drug Application (ANDA #217858) for Ketamine Hydrochloride Injection USP to a leading sterile-injectables pharmaceutical company.","length":498,"tagName":"p"},{"type":"text","content":"At closing, PharmaTher received a confidential upfront cash payment and remains eligible to receive additional milestone payments based on cumulative sales thresholds, as well as profit-sharing payments for seven years following first commercial sale. In total, the transaction provides the potential to generate more than US$25 million over time, subject to commercial performance.","length":382,"tagName":"p"},{"type":"text","content":"The sale strengthens PharmaTher's focus on the development and commercialization of the patented long-acting injectable ("LAI") ketamine program being advanced under an exclusive evaluation and option-to-license agreement with Oakwood Laboratories, LLC.","length":267,"tagName":"p"},{"type":"text","content":""Closing the ANDA sale marks the start of PharmaTher's next chapter," said Fabio Chianelli, Chairman and Chief Executive Officer of PharmaTher. "We have converted a legacy generic asset into non-dilutive capital and long-term upside, and we are now fully focused on building a differentiated, long-acting ketamine franchise for neuropsychiatric disorders."","length":380,"tagName":"p"},{"type":"text","content":"PharmaTher's LAI ketamine program leverages Oakwood's microsphere-based sustained-release technology, designed to enable subcutaneous or intramuscular administration with controlled drug release over weeks to months. The Company intends to pursue a 505(b)(2) regulatory pathway with an initial focus on high-value neuropsychiatric indications such as treatment-resistant depression (TRD), major depressive disorder (MDD), and Parkinson's disease.","length":458,"tagName":"p"},{"type":"text","content":""We believe long-acting ketamine is the natural evolution of today's ketamine treatment model,&q...