Business

Filana Therapeutics Announces Publication in Epilepsia of Preclinical Simufilam Data

Study in a well-accepted mouse model of severe Tuberous Sclerosis Complex (TSC) showed that simufilam attenuated the progression of seizures in a dose-dependent mannerResults confirm and extend previously published preclinical findingsTSC-related epilepsy affects approximately 45,000 people in the U.S. AUSTIN, Texas, April 15, 2026 (GLOBE NEWSWIRE) -- Filana Therapeutics, Inc. (NASDAQ: FLNA, “Filana Therapeutics”, the “Company”), a biotechnology company focused on developing therapies for Tubero

articleFilana Therapeutics, Inc.April 15, 20265/company/filana-therapeutics-inc/news/filana-therapeutics-announces-publication-in-epilepsia-of-preclinical-simufilam-data
Filana Therapeutics Announces Publication in Epilepsia of Preclinical Simufilam Data

About this update from Filana Therapeutics, Inc.

[{"type":"image","alt":"Filana Therapeutics, Inc.","displaySize":"","headline":null,"caption":"Filana Therapeutics, Inc.","className":"","disableSlideshowImg":false,"size":{"original":{"width":300,"height":300,"url":"https://media.zenfs.com/en/globenewswire.com/ec6f71a08700bedee385c3d7ccb26ead"},"resized":{"url":"https://s.yimg.com/ny/api/res/1.2/kE7v18uI46Kkd18JkU65nA--/YXBwaWQ9aGlnaGxhbmRlcjt3PTQyMDtoPTQyMA--/https://media.zenfs.com/en/globenewswire.com/ec6f71a08700bedee385c3d7ccb26ead","width":300,"height":300}},"lazy":false},{"type":"list","items":[{"val":[{"type":"text","content":"Study in a well-accepted mouse model of severe Tuberous Sclerosis Complex (TSC) showed that simufilam attenuated the progression of seizures in a dose-dependent manner","length":167,"tagName":"p"}]},{"val":[{"type":"text","content":"Results confirm and extend previously published preclinical findings","length":68,"tagName":"p"}]},{"val":[{"type":"text","content":"TSC-related epilepsy affects approximately 45,000 people in the U.S.","length":68,"tagName":"p"}]}],"tagName":"ul","bulletedList":true,"length":303,"olType":false},{"type":"text","content":"AUSTIN, Texas, April 15, 2026 (GLOBE NEWSWIRE) -- Filana Therapeutics, Inc. (NASDAQ: FLNA, “Filana Therapeutics”, the “Company”), a biotechnology company focused on developing therapies for Tuberous Sclerosis Complex (TSC)-related epilepsy, today announced publication in Epilepsia of preclinical data showing that simufilam attenuated seizure progression in a well-accepted mouse model of severe TSC-related epilepsy1. The results support the continued evaluation of simufilam for the treatment of TSC-related epilepsy, which affects approximately 45,000 people in the U.S.2,3. Simufilam is an oral small molecule intended to modulate filamin A protein.","length":654,"tagName":"p"},{"type":"text","content":"The study was led by Angélique Bordey, PhD, Senior Vice President, Neuroscience of Filana Therapeutics and Vice Chair of Research for the Department of Neurosurgery at Yale School of Medicine, and included a co‑author from Yale School of Medicine’s Departments of Neurosurgery and Cellular & Molecular Physiology. Top line results of the study were previously reported by the Company in August 2025. The work was conducted in collaboration with the TSC Alliance® and PsychoGenics, Inc., the clinical research partner of the TSC Precli...

More updates from Filana Therapeutics, Inc.

Tuberous Sclerosis ComplexTherapeuticsTSC Preclinical ConsortiumTSC Alliancemouse modelepilepsyTSCPsychoGenics, Inc.seizuresPsychoGenics