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EyePoint Pharmaceuticals Announces Upcoming Data Presentations at 2023 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting
- Positive neuroprotective effect of vorolanib, the active drug in EYP-1901, in a widely validated retinal detachment model demonstrates a potential new
About this update from Eyepoint, Inc.
[{"type":"text","content":"- Positive neuroprotective effect of vorolanib, the active drug in EYP-1901, in a widely validated retinal detachment model demonstrates a potential new mechanism of action for the treatment of retinal disease - - Clinical outcomes from real-world CALM registry study of YUTIQ® demonstrates effective control of inflammation in chronic posterior segment uveitis - WATERTOWN, Mass., March 20, 2023 (GLOBE NEWSWIRE) -- EyePoint Pharmaceuticals, Inc. (NASDAQ: EYPT), a company committed to developing and commercializing therapeutics to improve the lives of patients with serious eye disorders, today announced multiple scientific presentations at the 2023 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, being held April 23 – 27 in New Orleans, Louisiana. “We are excited to be presenting these positive data in support of EYP-1901 and YUTIQ at this year’s ARVO Annual Meeting,” said Jay Duker, M.D., President and Chief Operating Officer of EyePoint Pharmaceuticals. “We are particularly enthusiastic about the compelling preclinical data that highlights the potential neuroprotective effect of vorolanib, the active drug in EYP-1901, against photoreceptor degeneration in a validated retinal detachment model. These preclinical data on vorolanib bring an additional perspective to our positive Phase 1 DAVIO 12-month results, which will be showcased in an encore presentation at the meeting.” Dr. Duker added, “The preclinical data derived from a widely validated model of retinal detachment highlights vorolanib’s potential new mechanism of action for treating retinal diseases, and its unique benefits that set it apart from existing ligand binding biologics.” “These preclinical data demonstrate that vorolanib significantly reduced the severity of change in baseline visual acuity and improved contrast thresholds in mice treated with vorolanib compared with placebo, suggesting a neuroprotective effect against photoreceptor degeneration. Should this be reflected in clinical data, it would provide an important new mechanism of action for the treatment of these chronic, blinding retinal eye diseases such as wet AMD, diabetic retinopathy, diabetic macular edema and retinal vein occlusion. In addition, we will present important registry study data that demonstrates YUTIQ’s effective control of inflammation in real-world patients liv...