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EyePoint Pharmaceuticals Announces Completion of Enrollment of Phase 1 DAVIO Clinical Trial of EYP-1901 for the Potential Treatment of Wet AMD
WATERTOWN, Mass., May 25, 2021 (GLOBE NEWSWIRE) -- EyePoint Pharmaceuticals, Inc. (NASDAQ: EYPT), a pharmaceutical company committed to developing and
About this update from Eyepoint, Inc.
[{"type":"text","content":"WATERTOWN, Mass., May 25, 2021 (GLOBE NEWSWIRE) -- EyePoint Pharmaceuticals, Inc. (NASDAQ: EYPT), a pharmaceutical company committed to developing and commercializing therapeutics to help improve the lives of patients with serious eye disorders, today announced the completion of patient enrollment of its Phase 1 clinical trial of EYP-1901 as a potential twice-yearly sustained delivery anti-VEGF treatment targeting wet age-related macular degeneration (wet AMD). “We are pleased to report the completion of enrollment of all three dose cohorts in our ongoing Phase 1 trial of EYP-1901,” said Nancy Lurker, CEO of EyePoint Pharmaceuticals. “EYP-1901 represents an exciting potential advancement for the treatment of wet AMD as a twice-yearly therapy using our proven Durasert® technology that provides reliable, sustained, controlled and consistent zero order kinetics delivery. The completion of enrollment of our Phase 1 trial continues to make us confident that the potential advantages of EYP-1901 are obvious to patients and providers. We remain on track to provide interim data from the trial in the fourth quarter of 2021. We would like to thank our investigators and our internal team for making this enrollment possible and for their continued confidence in EYP-1901. The ongoing Phase 1 DAVIO trial for EYP-1901 is an open-label twelve-month dose escalation trial examining wet AMD patients who were responsive to previous anti-VEGF therapies. The primary endpoint of the trial is safety and key secondary endpoints are changes in best-corrected visual acuity (BCVA) and central subfield thickness. EYP-1901 is delivered via a single intravitreal injection in the physician's office. The Company anticipates that six-month interim data will include initial safety and efficacy evaluations. More information on the Phase 1 DAVIO trial may be found at www.clinicaltrials.gov (NCT04747197). About EYP-1901 EYP-1901 is a potential twice-yearly sustained delivery intravitreal anti-VEGF treatment for wet age-related macular degeneration, currently being studied in a Phase 1 clinical trial. EYP-1901 combines a bioerodible formulation of EyePoint’s proprietary Durasert® drug release technology and vorolanib, a tyrosine kinase inhibitor. Durasert provides sustained, controlled and consistent zero order kinetics drug delivery, and vorolanib demonstrated clear ...