Business
Esperion Therapeutics Closes Acquisition of Corstasis Therapeutics, Expanding Its Cardiovascular Franchise with Enbumyst™ (bumetanide nasal spray)
– Enbumyst, First and Only FDA-Approved Nasal Spray Loop Diuretic Now Integrated into Esperion’s Cardiovascular Franchise, Anticipated to Drive Portfolio
About this update from Esperion Therapeutics, Inc.
[{"type":"text","content":"– Enbumyst, First and Only FDA-Approved Nasal Spray Loop Diuretic Now Integrated into Esperion’s Cardiovascular Franchise, Anticipated to Drive Portfolio Expansion, Commercial Leverage, and Continued Revenue Growth – ANN ARBOR, Mich., April 02, 2026 (GLOBE NEWSWIRE) -- Esperion (NASDAQ: ESPR) (the Company) today announced the closing of its acquisition of Corstasis Therapeutics Inc., a privately-held, commercial-stage biopharmaceutical company advancing innovative outpatient therapies for the treatment of edema associated with cardiovascular and hepatic and renal disease. “The closing of this acquisition marks an important milestone in advancing our Vision 2040 and strengthens our commitment to delivering differentiated therapies that address the growing global burden of cardiometabolic disease,” said Sheldon Koenig, President and Chief Executive Officer of Esperion. “Enbumyst is a novel, patient-friendly option that we believe can meaningfully improve fluid management for congestive heart failure patients. We have ambitious long-term commercial plans for this product and expect it to support our revenue growth while further solidifying Esperion’s leadership in cardiometabolic risk management.” Through this acquisition, Esperion has acquired Corstasis, the developer and commercial sponsor of Enbumyst, the first and only FDA-approved nasal spray loop diuretic. Enbumyst received U.S. Food and Drug Administration (FDA) approval in September 2025 for the treatment of edema associated with congestive heart failure, as well as hepatic and renal disease in adults. With Enbumyst, Esperion expands its cardiovascular portfolio into an acute-adjacent, outpatient setting where convenience and patient adherence are critical. The Company intends to leverage its established cardiovascular commercial infrastructure, including payer engagement, prescriber education, and field execution capabilities, to drive adoption and maximize patient access to Enbumyst. Strategic Rationale Category-first innovation: Enbumyst is the first and only FDA-approved nasal spray loop diuretic, offering a convenient administration route for appropriate adult patients with edema associated with CHF and hepatic or renal disease.Commercial synergy: Esperion’s existing cardiovascular footprint, relationships, and infrastructure are expected to accelerate awareness, acces...