Wuxi Apptec Co., Ltd. Class ASSE: 603259

2026 JPM Presentation - WuXi AppTec 20260114

· Issued by Wuxi Apptec Co., Ltd. Class A
WuXi AppTec 2026 J.P. Morgan Healthcare Conference January 14, 2026


25 Years of Consistent Dedication: With Customers as Our Top Priority, Committed to Enabling Innovation and Bringing Breakthrough Treatments to Patients Worldwide

Our Vision

Large Pharmas

Quality Speed

Every drug can be made, and every disease can be treated.

Biotech Companies

Cost

3

3 Funding



Unique CRDMO (Contract Research, Development & Manufacturing Organization) Platform, Constantly Delivering Value to Customers Through Three Focused Core Business Segments



Research

Target to Hit Hit to Lead

Lead to PCC

Development

Preclinical Phase I Phase II Phase III

Manufacturing

Commercial Manufacturing

WuXi Biology

DEL/HTS, in vitro & in vivo Biology, Disease Models

WuXi Chemistry

CRDMO for Small Molecule and TIDES (Oligo & Peptide)

WuXi Testing

DMPK, Safety Assessment, Bioanalysis



4

Continued Strong Growth as A Leading Global CRDMO Company

~6,000

Active Customers across 30+

Countries over Past 12 Months

>4,000kL & >100kL

Total Reactor Volume of Small

Molecule & Peptide by End of 2025

>3,400

# of Molecules1in Small

Molecule CDMO Pipeline



RMB 45.5Bn

Total Revenue2in 2025, with Continuing Operations Growing 21.4% YoY

RMB 15.0Bn

Adjusted Non-IFRS Net Profit2in 2025, with 32.9% NPM (5.9pts YoY Increase)

RMB >55Bn

Strong Backlog1to Support

Sustainable Future Growth





5 Notes: 1. Data as of Q3 2025 for Continuing Operations (post divestiture of China-based clinical research services business).

2. Data per 2025 Positive Profit Alert (based on preliminary estimates); final results to be disclosed in the audited 2025 Annual Report (March 2026).

Continue to Invest in and Accelerate Enhancement of Global Capabilities & Capacities to Support Long-term Customer Demand and Future Growth

Boston New Jersey

Delaware

Munich Couvet

Changshu Wuxi



Tianjin Suzhou

Nantong

Changzhou

Taixing

San Diego

Chengdu Shanghai

Singapore

Jinshan

Nanjing

Wuhan

Reaching by end of 2025:

  • 120,000m2 GLP lab facility

  • >4,000kL small molecule APIs capacity

  • >100,000L solid phase peptide synthesizer capacity

6 Note: including main R&D and manufacturing sites; sales offices not included.

Sites under expansion/construction



Existing sites

Integrated Research Platforms (WuXi Chemistry1, WuXi Biology & WuXi Testing) Collaborate to Build Early-Stage Capabilities and Funnel Opportunities to Enhance CRDMO Business Model

Generate Flow, Understand Trends, and Achieve Synergy Through Accelerated PCC2& IND2Delivery









>9k



Customers Supported (2011-2025)





Enable Innovation from Discovery1& Preclinical1

100%

Top20 Global Pharma Partnership (2011-2025)

Build Long-term Trust with Customers

~65%

New Customers Onboarded to the Company

Entry Point for CRDMO Platform

>430k

Compounds Delivered in Q4 2024 - Q3 2025

Generate Downstream Opportunities

~30%

Joint IND2 Projects Supported

Drive Accelerated Conversion and Delivery





7 Notes: 1. WuXi Chemistry - Drug Discovery, and WuXi Biology together represent the Discovery platform; WuXi Testing represents the Preclinical platform.

2. PCC, Preclinical Candidate; IND, Investigational New Drug.

WuXi Chemistry: "Follow the Molecule + Win the Molecule", Small Molecule CRDMO Pipeline

Efficiently Converts and Captures High-Quality Molecules, Delivering Sustained Growth



"R" 430,000+ Compounds



Q1-Q3 2025 Newly

Added Molecules to D&M Pipeline

Including 250 Molecules

in Total 621

Converted from R to D

2,889 Preclinical & Phase I 374 Phase II 87 Phase III

16%

of Global Clinical Stage New Drugs (Q3 2025)



80

Commercial



8

Small Molecule D&M: Expansion of Phase III & Commercial Pipeline Continues to Drive Strong Growth

# of Small Molecule Phase III

& Commercial Drugs

Revenue of Small Molecule Phase III

& Commercial Drugs1

# of Molecules RMB billion

Phase III

>150%

10.3

9.0

4.6

H1

5.4



Commercial

107

87

127

167

152

+56%

80

72

61

50

57

66

80



2022 2023 2024 Q3 2025 2022 2023 2024 2025E



9 Note: 1. Excluding COVID-19 commercial project.

US FDA New Drug Approvals by Modality (2025)

1

3

4

30

17

Biologics

31%

Small Molecule 55%

CGT 7%

Oligo 5%

Peptide 2%



Supported 8 out of 30 Small Molecule Drugs Approved by US FDA in 2025, Timely Addressing Unmet Needs for Patients



Supported 27% of new drugs approved in 2025





10 Source: FDA (CDER & CBER); internal analysis. This analysis includes novel approvals and therapeutics only.



Securing Fast Growing Market for Glucagon-Like Peptide-1 Agonists (GLP-1)

Currently Supporting 24 GLP-1 Drugs

Clinical Stage Peptide Drugs

Clinical Stage Small Molecule Drugs

Marketed NCE

Drugs

  1. out of 56

  2. out of 36

1 out of 7

WuXi Chemistry is supporting 15 GLP-1 small molecule and peptide new drugs currently in Phase II and Phase III clinical trials, securing 25% of the market share

Estimated global sales of GLP-1 drugs in 2030 will reach $145B, 2.7x of the sales in 2024



11 Source: Evaluate Pharma, Mechanism of Action "Glucagon-like peptide 1 (GLP-1) receptor agonist", January 2026.

TIDES (Oligo & Peptide): Continued Rapid Business Growth Driven by Enhanced Capabilities and Fast Growing Capacities

TIDES Revenue Solid Phase Peptide Synthesizer

Total Reactor Volume

RMB billion Liter

>100,000

41,000

32,000

500

2,000

4,000

6,000

>90%

5.8

3.4

2.0

Q1-Q3

7.8

0.3

0.8



2020 2021 2022 2023 2024 2025E 2019 2020 2021 2022 2023 2024 2025



12

Navigating Through Cycles with Continued Growth in Revenue and Profitability

2025 Full-Year Again Beats Expectations: 21.4% YoY Growth in Continuing Operations Revenue, Total Revenue Reaching 45.5

Billion, and Adjusted Non-IFRS NPM% Further Improved to 32.9%

Revenue

Adjusted Non-IFRS Net Profit Attributable

to the Owners of the Company

RMB billion RMB billion

22.0%

22.4%

23.9%

26.9%

27.0%

32.9%

CAGR +22.4%

+15.8%

45.5

39.4

40.3

39.2

22.9

16.5



Excluding COVID-19 Commercial Project
COVID-19 Commercial Project

Adjusted Non-IFRS NPM%

CAGR +32.7%

+41.3%

15.0

9.4

10.9

10.6

3.6

5.1



2020 2021 2022 2023 2024 2025E12020 2021 2022 2023 2024 2025E1



13 Note: 1. Data per 2025 Positive Profit Alert (based on preliminary estimates); final results to be disclosed in the audited 2025 Annual Report (March 2026).

Sustained Positive Free Cash Flow Driven by Continued Business Growth, Efficient Operations and Constant Improvement of Financial Management Capabilities

Continue to Invest in Global Capabilities & Capacities, Talents, and Reward Shareholders

RMB billion

Capex1

Operating Cash Flow

12.6

12.0

10.0

10.2

6.9

5.5

5.5-6.0

3.8

4.4

4.0

3.0



2020 2021 2022 2023 2024 2025E



14 Note: 1. Capex includes purchase of property, plant and equipment, other intangible assets and other long-term expenses.

Enabling Value Creation and Consistent Shareholder Returns

Basic Earnings per Share (EPS)1

Continue to Improve

Dividends & Share Buybacks

RMB20 Billion in Total Since IPO

RMB RMB billion

Dividends Declared & Paid

7.1

6.9

4.2

2.6

1.5

4.9

0.7

0.6

0.9

2.9

2019

2020

2021

2022

2023

2024

2025

2.0

Share Buybacks for Cancellation

~10x

6.7

3.0

3.3

3.3

1.8

0.7

1.1



2019 2020 2021 2022 2023 2024 2025E2



15 Notes: 1. Restate 2019 & 2020 EPS to reflect the changes in shares volume according to 2020 Profit Distribution Plan as per 2020 Annual Report.

2. Data per 2025 Positive Profit Alert (based on preliminary estimates); final results to be disclosed in the audited 2025 Annual Report (March 2026).

Advancing Sustainability, with Credibility Recognized by Global Authority Ratings & Initiatives

Achieved "AAA" from MSCI, "A" from CDP Climate Change & Water Security, and "Gold" from EcoVadis in 2025; Near-term

Achieved MSCI's highest "AAA"

rating for the first time in 2025; leadership ratings for 5 consecutive years

Improved to the highest

"A" rating in CDP Climate Change in 2025 for the first time

"A" rating in CDP Water

Security for 2 consecutive years in 2024-2025

"Gold" rating by EcoVadis

for 2 consecutive years in 2024-2025



Emissions Reduction Targets Validated by SBTi



Near-term emissions reduction targets validated by SBTi in 2025

16

Joined the United Nations Global Compact (UNGC) in 2024

Joined the Pharmaceutical Supply Chain Initiative (PSCI) as a Supplier partner in 2024

Named to S&P Global DJSI for 4 consecutive years



in 2021-2024

Unwavering Commitment to Guarding Customers' IP and Adhering to the Highest Standards

60

Information Security Audits by Global Customers in 2025, with 0 Critical Findings



of Quality & Compliance

741

Quality Audits & Inspections1 by Global Customers, Regulatory Authorities and Independent Third Parties in 2025







100%

Pass Rate with

0 Critical Findings



20

Main Operating Sites2are

ISO/IEC 27001 Certified

17 Notes: 1. Including 680 audits by customers, 56 inspections by regulatory authorities, and 5 audits by independent third parties.

2. Including all main operating sites in China for Continuing Operations (post divestiture of China-based clinical research services business).

Steering the Next 25 Years with Our Unique CRDMO Business Model and Operational Excellence, Positioning the Company to Continue Growth Through All Times



Continue to focus on our unique CRDMO core business, providing exceptional services to

01 customers and benefiting patients worldwide

02 Invest in and accelerate global enhancement of capabilities & capacities,

supporting long-term customer demand and innovation

03 Follow the science, and develop in-depth industry insights to secure new molecule opportunities, driving the next wave of accelerated growth

04 Maintain organizational agility and elevate operational excellence, continuing to deliver services with superior efficiency and quality

05 Sustain resilient profitability and operating cash flow, enabling value creation by consistent investment in business growth, talents and rewarding shareholders



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