Viking Therapeutics Presents New Data from Phase 2 Study of VK2809 in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD) and Elevated LDL-Cholesterol at The Digital International Liver Congress™ 2020

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VK2809-Treated Patients Maintain Durable, Statistically Significant Liver Fat Reductions at Week 16, Four Weeks Following Last Study Dose Significant Reductions in Week 12 Liver Fat Content Achieved Across Spectrum of Baseline Characteristics and Common NASH Risk Factors SAN DIEGO, Aug. 28, 2020 /PRNewswire/ -- Viking Therapeutics, Inc. (Viking) (NASDAQ: VKTX), a clinical-stage biopharmaceutical company focused on the development of novel therapies for metabolic and endocrine disorders, today announced the presentation of new results from the company's 12-week Phase 2 study of VK2809 in patients with non-alcoholic fatty liver disease (NAFLD) and elevated low-density lipoprotein cholesterol (LDL-C) at the Digital International Liver Congress™ 2020. The study results were featured in an oral presentation at the annual meeting of the European Association for the Study of the Liver (EASL), being held virtually August 27-29, 2020. Highlights from the oral presentation include newly reported data demonstrating that patients treated with VK2809 experienced durable, statistically significant reductions in liver fat content that were maintained at Week 16, four weeks after administration of the last dose in the 12-week study. Additionally, new analyses of 12 week study results demonstrated that patients receiving VK2809 experienced significant reductions in liver fat content irrespective of various baseline characteristics and common risk factors for non-alcoholic steatohepatitis (NASH). Data presented at The Digital International Liver Congress 2020 include: Reduction in Liver Fat Content at Week 16 At Week 16, four weeks following completion of treatment, study results demonstrated that VK2809-treated patients maintained statistically significant reductions in liver fat content, both as compared to baseline and as compared to placebo. VK2809-treated patients experienced a statistically significant median reduction in liver fat content of 45.4% at Week 16 as compared to an 18.7% reduction for placebo. Additionally, at Week 16, 70.4% of all VK2809-treated patients were still considered responders, experiencing ≥ 30% relative reduction from baseline in liver fat content, as compared to 22.2% for placebo-treated patients. Of note, 100% of patients receiving 5 mg of VK2809 dosed daily were still considered responders at Week 16. These results highlight the durability...

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