| Revolution Medicines, Inc. | 1.11M | US$207M | 10.1% |
| Travere Therapeutics, Inc. | 2.18M | US$124M | 6.0% |
| Eli Lilly And Company | 98,700 | US$118M | 5.8% |
| Madrigal Pharmaceuticals, Inc. | 175K | US$94M | 4.6% |
| Mirum Pharmaceuticals, Inc. | 798K | US$93.4M | 4.6% |
| Rhythm Pharmaceuticals, Inc. | 693K | US$76.9M | 3.8% |
| Kymera Therapeutics, Inc. | 453K | US$52M | 2.5% |
| Argenx Se | 52,750 | US$48.9M | 2.4% |
| Xenon Pharmaceuticals Inc. | 684K | US$41.3M | 2.0% |
| Scholar Rock Holding Corporation | 715K | US$39.3M | 1.9% |
| Insmed Incorporated | 362K | US$38.6M | 1.9% |
| Penumbra, Inc. | 116K | US$36.5M | 1.8% |
| Ultragenyx Pharmaceutical Inc. | 968K | US$32.3M | 1.6% |
| Irhythm Holdings, Inc. | 270K | US$32.1M | 1.6% |
| Intuitive Surgical, Inc. | 76,460 | US$30.4M | 1.5% |
| Agilon Health, Inc. | 263K | US$28.1M | 1.4% |
| Unitedhealth Group Incorporated | 63,750 | US$26.5M | 1.3% |
| Celldex Therapeutics, Inc. | 699K | US$26M | 1.3% |
| Erasca, Inc. | 1.4M | US$25.7M | 1.3% |
| Neurocrine Biosciences, Inc. | 145K | US$24.4M | 1.2% |
| Enliven Therapeutics, Inc. | 465K | US$23.6M | 1.2% |
| Tenet Healthcare Corporation | 125K | US$23.4M | 1.1% |
| Dexcom, Inc. | 343K | US$23.1M | 1.1% |
| Aclaris Therapeutics, Inc. | 4.33M | US$22.9M | 1.1% |
| Minimed Group, Inc. | 1.52M | US$22.7M | 1.1% |
| Boston Scientific Corporation | 529K | US$22.6M | 1.1% |
| Avalyn Pharma Inc. | 663K | US$21.8M | 1.1% |
| Hemab Therapeutics Holdings, Inc. | 575K | US$21.1M | 1.0% |
| Dyne Therapeutics, Inc. | 942K | US$20.9M | 1.0% |
| Alnylam Pharmaceuticals, Inc. | 66,750 | US$20.1M | 0.98% |
| Cogent Biosciences, Inc. | 516K | US$20M | 0.97% |
| Agios Pharmaceuticals, Inc. | 533K | US$19.8M | 0.96% |
| Vera Therapeutics, Inc. | 428K | US$18.3M | 0.90% |
| Tarsus Pharmaceuticals, Inc. | 277K | US$17.4M | 0.85% |
| Heartflow, Inc. | 574K | US$16.8M | 0.82% |
| Mbx Biosciences, Inc. | 298K | US$16.5M | 0.80% |
| Cytokinetics, Incorporated | 188K | US$16M | 0.78% |
| Bicara Therapeutics Inc. | 535K | US$15.9M | 0.78% |
| Parabilis Medicines, Inc. | 578K | US$15.8M | 0.77% |
| Zai Lab Ltd. | 815K | US$15.5M | 0.76% |
| Danaher Corporation | 76,300 | US$14.5M | 0.71% |
| Tango Therapeutics, Inc. | 457K | US$14.3M | 0.70% |
| Evolent Health, Inc | 2.5M | US$13.6M | 0.66% |
| Ptc Therapeutics, Inc. | 162K | US$13.2M | 0.65% |
| Mineralys Therapeutics, Inc. | 485K | US$13.1M | 0.64% |
| Zenas Biopharma, Inc. | 502K | US$12.7M | 0.62% |
| Ardelyx, Inc. | 2.24M | US$11.4M | 0.56% |
| Inspire Medical Systems, Inc. | 244K | US$10.9M | 0.53% |
| Bridgebio Pharma, Inc. | 145K | US$10.8M | 0.53% |
| Summit Therapeutics Inc. | 715K | US$10.4M | 0.51% |
| Azenta, Inc. | 403K | US$10.3M | 0.50% |
| Indivior Pharmaceuticals, Inc. | 246K | US$10.1M | 0.49% |
| Stryker Corporation | 29,000 | US$9.13M | 0.45% |
| Amylyx Pharmaceuticals, Inc. | 500K | US$8.98M | 0.44% |
| Caris Life Sciences, Inc. | 488K | US$8.69M | 0.42% |
| Omada Health, Inc. | 373K | US$8.19M | 0.40% |
| Compass Therapeutics, Inc. | 3.52M | US$7.72M | 0.38% |
| Immunome, Inc. | 348K | US$7.37M | 0.36% |
| Phreesia, Inc. | 697K | US$7.17M | 0.35% |
| Omeros Corporation | 718K | US$6.83M | 0.33% |
| Definium Therapeutics, Inc. | 143K | US$6.74M | 0.33% |
| Corcept Therapeutics Incorporated | 72,000 | US$6.26M | 0.31% |
| Janux Therapeutics, Inc. | 367K | US$5.64M | 0.28% |
| Mobia Medical, Inc. | 418K | US$5.6M | 0.27% |
| Arcus Biosciences, Inc. | 180K | US$5.55M | 0.27% |
| Thermo Fisher Scientific Inc | 10,000 | US$5.01M | 0.24% |
| Trevi Therapeutics, Inc. | 260K | US$4.85M | 0.24% |
| Sionna Therapeutics, Inc. | 99,429 | US$4.37M | 0.21% |
| Cvs Health Corporation | 40,000 | US$4.14M | 0.20% |
| Eyepoint, Inc. | 269K | US$3.84M | 0.19% |
| Ocular Therapeutix, Inc. | 384K | US$3.77M | 0.18% |
| Spyre Therapeutics, Inc. | 42,254 | US$3.75M | 0.18% |
| Talphera, Inc. | 3.59M | US$3.7M | 0.18% |
| Roivant Sciences Ltd. | 101K | US$3.57M | 0.17% |
| Vaxcyte, Inc. | 60,250 | US$3.5M | 0.17% |
| Neurogene Inc. | 107K | US$3.36M | 0.16% |
| Century Therapeutics, Inc. | 1.3M | US$3.2M | 0.16% |
| Alphatec Holdings, Inc. | 360K | US$3.11M | 0.15% |
| Novo Nordisk A/s Class B | 63,500 | US$3.04M | 0.15% |
| Olema Pharmaceuticals, Inc. | 235K | US$2.94M | 0.14% |
| Nervgen Pharma Corp. | 1.21M | US$2.49M | 0.12% |
| Teva Pharmaceutical Industries Limited | 59,000 | US$2M | 0.10% |
| Dianthus Therapeutics, Inc. | 20,326 | US$1.98M | 0.10% |
| Sagimet Biosciences Inc. - Series A | 250K | US$1.93M | 0.09% |
| Capricor Therapeutics, Inc. | 74,448 | US$1.79M | 0.09% |
| Lenz Therapeutics, Inc. | 257K | US$1.46M | 0.07% |
| Altimmune, Inc. | 471K | US$1.43M | 0.07% |
| Kailera Therapeutics, Inc. | 65,000 | US$1.43M | 0.07% |
| Surgery Partners, Inc. | 84,000 | US$1.41M | 0.07% |
| Axsome Therapeutics, Inc. | 5,500 | US$1.35M | 0.07% |
| Oruka Therapeutics, Inc. | 12,051 | US$1.15M | 0.06% |
| Viking Therapeutics, Inc. | 25,500 | US$995K | 0.05% |
| Glaukos Corporation | 4,750 | US$664K | 0.03% |
| Jasper Therapeutics, Inc. | 1.1M | US$463K | 0.02% |
| Biocryst Pharmaceuticals, Inc. | 22,124 | US$221K | 0.01% |
| Apellis Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Ascendis Pharma A/s | 0 | US$0 | 0.00% |
| Edwards Lifesciences Corporation | 0 | US$0 | 0.00% |
| Gossamer Bio, Inc. | 0 | US$0 | 0.00% |
| Regeneron Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |