Ligand Pharmaceuticals Incorporated · NASDAQ:LGND

Ligand Pharmaceuticals — Q1 2025 Earnings Presentation

16 slides from Ligand Pharmaceuticals's earnings presentation, May 8, 2025

  1. Slide 1: First Quarter 2025 Financial Results

    MAY 8, 2025 First Quarter 2025 Financial Results

  2. Slide 2: Safe Harbor Statement and Disclaimers

    Safe Harbor Statement and Disclaimers • This presentation contains forward-looking statements, as defined in Section 21E of the Securities Exchange Act of 1934, by Ligand and its partners that involve risks and uncertainties and reflect Ligand’s and its partners’ judgment as of the date of this pres

  3. Slide 3: 2025 Highlights

    2025 Highlights 46% Q1’25 revenue growth over Q1’24, 11% Q1’25 adjusted EPS1 growth over Q1’24 FINANCIAL Strong financial performance Cash and investments of $209 million, no debt, >$400 million in deployable capital with access to $125 million credit facility (expandable to $200 million) Invested ~

  4. Slide 4: Q1 2025 Investment Activity

    Q1’ 2025 Investment Activity Record setting quarter of 80+ Investments Reviewed origination. Our experienced team is quick to focus on highest value opportunities 38 active investment opportunities under 38 Under Review review; even balance between accretive and pre-approval investments 2 Conducted

  5. Slide 5: Ligand Strategic Differentiation

    Ligand Strategic Differentiation STRONG FINANCIALS High-margin / high-growth strategy Superior P&L, low op-ex with lean operations, high profits per employee Predictable and diversified growth ADVANTAGEOUS STRATEGY High Demand: Inefficient market with inexhaustible demand for capital Superior Inform

  6. Slide 6: Looking Ahead To 2029

    Looking Ahead To 2029 Expected Royalty Receipts CAGR 22% from 2024-2029 Looki Current portfolio of commercial and late-stage programs + new deals drive growth ng • Long–term royalty receipt outlook on Ligand Expected Royalty Receipts ($M) 4% Ahea Future CAGR pace to meet or exceed 22% CAGR Investmen

  7. Slide 7: Investment Update

    Investment Update Rich Baxter

  8. Slide 8: Pelthos Transaction Overview

    Pelthos Transaction Overview Enables the combined company to focus on accelerating the launch of ZELSUVMITM in the U.S. Investment proceeds will be used to fund launch preparation efforts and company operations Transaction Highlights • Merger with Channel Therapeutics, which will be renamed Pelthos

  9. Slide 9: Zelsuvmi Is the First and Only At-Home Treatment for MC

    Zelsuvmi Is the First and Only At-Home Treatment for MC That Offers a First-Line Efficacious and Safe Treatment Option Zelsuvmi Vision Zelsuvmi is the first and only at-home treatment that could revolutionize how MC is treated today for patients greater than 1 year old First product to be FDA-approv

  10. Slide 10: Significant Updates Since Ligand's Acquisition in Fall 2023

    Significant Updates Since Ligand’s Acquisition in Fall 2023 FDA Approval for Zelsuvmi Ligand Investment Commercial Launch Strategy • First and only product approved by FDA for MC • Established Pelthos as a wholly-owned • Well-positioned to be first line therapy treating infections for use at home by

  11. Slide 11: Pelthos Commercial Leadership

    Pelthos Commercial Leadership Pelthos’ management and board has extensive experience successfully commercializing products to both pediatricians and dermatologists Management Team and Board Members with Extensive Commercial Experience Scott Plesha • Prior to joining Pelthos, Mr. Plesha was President

  12. Slide 12: Financial Update

    Financial Update Tavo Espinoza

  13. Slide 13: Q1'25 Financial Highlights

    Q1’25 Financial Highlights Q1 2025 Total Revenue Q1 2025 Royalties $45.3M $27.5M 2025 Full Year Guidance $180-$200M 44% increase vs Q1 2024 Q1 2025 Adjusted EPS1 Cash & Investments3 $1.33 $209M 2025 Full Year Guidance $6.00-$6.252 >$400M in Deployable Capital as of March 31, 2025 1. Adjusted EPS rep

  14. Slide 14: Q1'25 Financial Performance

    Q1’25 Financial Performance $ in millions, except for per share amounts (unaudited) Three Months Ended March 31, 2025 2024 Revenues: Royalties $27.5 $19.1 • Q1’25 royalty revenue grew 44% Captisol 13.5 9.2 driven by Filspari, Contract revenue 4.4 2.7 Total revenues 45.3 31.0 Ohtuvayre,Capvaxive and

  15. Slide 15: Ligand 2025 Financial Guidance

    Ligand 2025 Financial Guidance 2025 Financial 2022 Actuals 2023 Actuals 2024 Actuals Guidance Royalties $73M $85M $109M $135-140M Core Captisol Sales1 $16M $28M $31M $35-40M Contract Revenue $19M $18M $27M $10-20M Total Core Revenue1 $108M $131M $167M $180-200M Adjusted Core EPS2 $2.44 $4.06 $5.74 $

  16. Slide 16: LIGAND

    LIGAND

Ligand Pharmaceuticals — Q1 2025 Earnings Presentation on 6ix