Medtronic Plc. · NYSE:MDT

Medtronic — Investor Presentation

32 slides from Medtronic's investor presentation

  1. Slide 1: Welcome

    Welcome <Provider(s) name (s)> <Practice name> <City, State> <Phone Number> 1 UC202104214b EN

  2. Slide 2: You deserve more from your bladder and bowel control

    You deserve more from your bladder and bowel control Experience more freedom, more life, and more control.

  3. Slide 3: It's time for this to change

    Will I ever regain How can I possibly go on control? a date? One survey showed 44% that Attend an outdoor Get a job? celebration? of people say they are embarrassed to talk about I’m afraid to leave The bathroom is always on and more than bladder control problems?1 50% home my mind; it’s embarrassin

  4. Slide 4: Bladder and bowel issues aren't inevitable

    Bladder and bowel issues aren’t inevitable Do the following sound familiar? Urinating more than Monitoring how much eight times a day you eat or drink Getting the “have to go Using pads to control NOW” feeling leaks Planning activities Getting up multiple around the bathroom times a night If so, you

  5. Slide 5: You are not alone

    You are not alone Bowel control problems affect an estimated Incontinence affects people of all ages 1 in 12 U.S. adults4,5 Bladder control problems Ignoring bladder and bowel control affect an estimated That’s 21.4 million problems can lead to more issues:1 adults.3,4,5 • Loss of sleep 1 in 6 • Los

  6. Slide 6: The good news?

    The good news? Bladder and bowel treatments can get you back to more freedom, more life, and more control.

  7. Slide 7: What causes bladder and bowel control problems?

    What causes bladder and bowel control problems? • Daily habits, including what you eat and drink • Medications or supplements you take • Pregnancy, childbirth, or pelvic floor injury 7 UC202312662 EN

  8. Slide 8: How does bladder control work?

    How does Nerves signal your brain to empty your bladder control work? bladder Bladder/brain communication is essential for bladder and bowel control. Kidneys produce urine and send it to the bladder Communication breakdowns may cause bladder control problems.1,2,3 Unlike conventional treatments, sac

  9. Slide 9: How does bowel control work?

    How does Nerves signal your bowel control work? brain to relax the anal sphincter muscles Bowel/brain communication is The digestive system pushes food essential for bowel control. through the intestines Communication breakdowns may cause bowel control problems.2 When the rectum is full, it stimulat

  10. Slide 10: Three common bladder control problems

    Three common bladder control problems 1 2 3 Stress incontinence Urinary retention Overactive bladder (OAB) 10 UC202312662 EN

  11. Slide 11: What is stress incontinence?

    What is stress incontinence? “Any little thing can • Leaking when you sneeze, cough, or laugh • Leaking when you exercise, bend, or lift • Leaking when you climb stairs or stand up trigger a leak and it’s • Going all the time to avoid having an accident driving me crazy.” 11 UC202312662 EN

  12. Slide 12: What is urinary retention?

    What is urinary retention? • Can’t tell if your bladder is full “It’s incredibly • Unable to fully empty your bladder frustrating to have • Weak or dribbling stream something so • Needing to use a catheter simple cause this big of a problem.” 12 UC202312662 EN

  13. Slide 13: What is overactive bladder (OAB)?

    What is overactive bladder (OAB)? Urge incontinence • Going before you reach the bathroom “I never drink • Frequent leaks anything during • After drinking a small amount of liquid • When hearing or touching running water meetings because I’m • Using pads or protective garments afraid I might leak.”

  14. Slide 14: What is fecal incontinence?

    What is fecal incontinence? Recurring condition with frequent accidents • Urge incontinence ‒ inability to resist the urge to go • Passive incontinence ‒ inability to feel when you need to go Do the following sound familiar? • Planning activities around the bathroom • Involuntary loss of stool • Sto

  15. Slide 15: Find more control

    Find more control There are many ways to treat incontinence1 and get back to living life. Lifestyle Oral Advanced changes medications* therapies *Only valid for urinary incontinence 1. American Urological Association. Diagnosis and treatment of non-neurogenic overactive bladder (OAB) in adults: an A

  16. Slide 16: Lifestyle changes

    Lifestyle changes Simple solutions can help some people but may not work very well (or at all) for others.1 • Diet • Exercise • Bladder and bowel retraining (biofeedback) • Pelvic floor strengthening (Kegels) 1. American Urological Association. Diagnosis and treatment of non-neurogenic overactive bl

  17. Slide 17: Oral medications for bladder

    Oral medications 72% In one survey, for bladder Oral medications can control symptoms, but of people said they stopped they don’t always work, and they may cause taking bladder medication within six months.2 other issues. • Medications must be taken daily • Medications often have unpleasant side eff

  18. Slide 18: Patient (dis)satisfaction

    Patient (dis)satisfaction High dissatisfaction Only 20% of OAB 82% of OAB patients patients are “extremely are non-adherent to satisfied” with their medications at 12 current treatment1 months2 High OAB patient attrition 60% 80% 90% of patients do not of patients do not of patients do not return aft

  19. Slide 19: Advanced therapies

    Advanced therapies If conservative treatments don’t deliver the results you expected, you may have other, more effective options. Bladder control Bowel control 1. Sacral Neuromodulation 1. Sacral Neuromodulation (SNM) (SNM) 2. Percutaneous Tibial 2. Other surgical options Neuromodulation (PTNM) 3. I

  20. Slide 20: Injected medications

    Injected medications Injections can temporarily treat bladder control but may raise other concerns. • Medicine is injected into multiple areas of the 67% One study found bladder muscle1 • Effectiveness is comparable to oral medications2 • Does not address bladder/brain communication1 of patients dis

  21. Slide 21: Percutaneous Tibial Neuromodulation (PTNM)

    Percutaneous Tibial “PTNM has improved my Neuromodulation (PTNM) quality of life. It is such a relief not to have to be worrying about my bladder needs. It’s a nice sense of freedom.” —Mary D., experiencing relief with • Safe, effective, minimally invasive therapy percutaneous tibial neuromodulation

  22. Slide 22: Sacral neuromodulation (SNM)

    Sacral neuromodulation (SNM) More than 375,000 people worldwide have had this therapy • Gentle nerve stimulation targets the communication pathway between the brain and bladder/bowel and restores* bladder/bowel function.1,2 • Sacral neuromodulation (SNM) is more effective than medication.3,4,5 • A t

  23. Slide 23: Take back control

    Take back control • The simple test starts at your doctor’s office or an outpatient center. • A small battery and wire are used in an outpatient setting. • The lead attaches to a small external device worn discreetly under your clothes. • Go about your regular activities for up to 14 days. • Record

  24. Slide 24: Commitment to Sacral Neuromodulation

    Commitment to Sacral Neuromodulation 25 years of therapy innovation across the globe 1982 1994 1997 1999 2000 2002 2006 2007-2019 2009 2011 1st SNM Implant CE Mark: FDA Approval: FDA Approval: CE Mark: FDA Approval: FDA Approval: Investment: FDA Approval: FDA Approval: During clinical trials InterSt

  25. Slide 25: Is this therapy right for you?

    Is this therapy right for you? You may be a good candidate for bladder and bowel control therapy delivered by sacral neuromodulation (SNM) if: You have significant symptoms You’ve tried lifestyle changes and oral medications These treatments haven’t given you the relief you want 25 UC202312662 EN

  26. Slide 26: Trust a proven therapy

    Trust a proven therapy 84% 3X 89% The most common adverse events experienced during clinical studies included pain at implant sites, new pain, lead migration, infection, satisfaction among greater improvements in of people using Sacral technical or device problems, those who use it2 for quality of l

  27. Slide 27: I'm not living in the bathroom — I'm living my life!

    I’m not living in the bathroom — I’m living my life! Mitzi, Experiencing relief with Sacral Neuromodulation for Bowel Control 27 UC202312662 EN Not all patients will experience similar results.

  28. Slide 28: Questions?

    Questions? 28 UC202312662 EN

  29. Slide 29: Thank you

    Thank you

  30. Slide 30: Medtronic Bladder Control Therapy indications and risks

    Medtronic Bladder Control Therapy delivered by the InterStim™ system treats urinary retention (inability to completely empty the bladder) and the symptoms of overactive bladder, including urinary urge incontinence (leakage) and significant symptoms of urgency-frequency. It should be used after you h

  31. Slide 31: Medtronic Bowel Control Therapy indications and risks

    Medtronic Bowel Control Therapy delivered by InterStim™ system treats chronic fecal incontinence (an accident or leaking involving stool). It should be used after you have tried other treatments such as medications and dietary modifications and they have not worked, or if you are not a candidate for

  32. Slide 32: Thank you

    Thank you

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