Merck & Company, Inc. · NYSE:MRK

Merck & — JP Morgan 2016 Healthcare Conference

12 slides from Merck &'s conference presentation, Jan 11, 2016

  1. Slide 1: JP Morgan 2016 Healthcare Conference

    Merck & Co., Inc. JP MORGAN 2016 HEALTHCARE CONFERENCE January 11, 2016 Ken Frazier CHAIRMAN & CHIEF EXECUTIVE OFFICER 1

  2. Slide 2: Forward-Looking Statement of Merck & Co., Inc.

    FORWARD-LOOKING STATEMENT OF MERCK & CO., INC., KENILWORTH, NJ, USA This presentation of Merck & Co., Inc., Kenilworth, NJ, USA (the “company”) includes “forward-looking statements” within the meaning of the safe harbor provisions of the United States Private Securities Litigation Reform Act of 1995

  3. Slide 3: Global Healthcare Market Is Evolving

    Global Healthcare Market Is Evolving INCREASED CHALLENGE TO ADVANCES IN DEMAND FOR SYSTEM SCIENCE AND HEALTHCARE SUSTAINABILITY TECHNOLOGY DRIVING A FOCUS ON INNOVATION AND VALUE 3

  4. Slide 4: Merck Has A Rich Heritage Of Bringing Groundbreaking Products To Market

    Merck Has A Rich Heritage Of Bringing Groundbreaking With Potential Products To Market Future Innovations ALZHEIMER’S • MMR • INTRON A • VARIVAX • JANUVIA • KEYTRUDA AMR • PRIMAXIN • RECOMBIVAX • FOSAMAX • GARDASIL • BELSOMRA • PNEUMOVAX • ZOCOR • CRIXIVAN • ISENTRESS • VICTRELIS ATHEROSCLEROSIS • M

  5. Slide 5: Remains Committed to Being The Premier Research-Intensive Biopharmaceutical Company

    Merck Remains Committed to Being The Premier Research-Intensive Biopharmaceutical Company Innovate Pursue the most promising science to address significant unmet medical needs Adapt Execute Develop culture and business Prioritize resources to model that evolve with internal high-growth areas, key an

  6. Slide 6: We Are Executing On Our Strategy

    R&D MAJOR PRODUCT APPROVALS * We Are • KEYTRUDA, GARDASIL 9, BELSOMRA, BRIDION Executing OTHER KEY FILINGS * • Hepatitis C Doublet, Bezlotoxumab On Our ADVANCED PIPELINE * • ~20 programs advanced into Phase 2 or 3 Strategy COMMERCIAL • Continued growth of the JANUVIA franchise • Successful launch of

  7. Slide 7: 1st Anti-PD1 To Market

    • NSCLC: Approved in 2L; KN-010 data show Superior OS vs. docetaxel • Melanoma: Approved in 1L+; Superior OS vs. ipilimumab • FDA Breakthrough Therapy Designation in 3 tumor types • >10 internally-owned I/O mechanisms with several expected 1st Anti-PD1 in the clinic by YE 2016 To Market • Broadest c

  8. Slide 8: Merck Continues to Invest in its Robust Pipeline

    Merck Continues to Invest in its Robust Pipeline* Alzheimer's Disease Diabetes Mellitus Vaccines Bacterial Infection HIV Cancer Neurosciences Alzheimer's Disease Cancer Asthma Heart Failure >20 Phase I/PoC Bacterial Infection Pneumococcal Vaccine >10 Phase IIb Allergy Cancer Herpes Zoster Vaccine Al

  9. Slide 9: Business Development Is A Key Enabler Of Our Strategy

    Business Development Is A Key Enabler Of Our Strategy Early immunotherapy Adds NUC to Hospital Acute candidates HCV pipeline Care Soluble guanylate ~ 30 oncology partnerships cyclase modulators & collaborations cCam Biotherapeutics Idenix Cubist Bayer Oncology Moderna NGM … more to come Messenger No

  10. Slide 10: Key Potential Catalysts for 2016: Anticipated Data, Filings and Approvals

    Key Potential Catalysts for 2016: Anticipated Data, Filings and Approvals DATA FILINGS APPROVALS • KEYTRUDA • KEYTRUDA filings in • HCV Doublet o Registration enabling several tumor types study completions in multiple tumor types • Bezlotoxumab including 1L NSCLC • Odanacatib filing o Initial GITR d

  11. Slide 11: Committed to Creating Long-Term Value

    Committed to Creating Long-Term Value Innovate Adapt Execute 11

  12. Slide 12: JP Morgan 2016 Healthcare Conference

    Merck & Co., Inc. JP MORGAN 2016 HEALTHCARE CONFERENCE January 11, 2016 Ken Frazier CHAIRMAN & CHIEF EXECUTIVE OFFICER 12

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