Angiodynamics, Inc. · NASDAQ:ANGO

Angiodynamics — Investor Day (April 2025)

24 slides from Angiodynamics's investor day presentation, Apr 2, 2025

  1. Slide 1: Shaping the Future of Cardiovascular Care: Innovative Technologies. Improved Outcomes.

    INVESTOR EVENT Shaping the Future of Cardiovascular Care: Innovative Technologies. Improved Outcomes.

  2. Slide 2: Forward Looking Statements

    Forward Looking Statements Forward Looking Statements Notice Regarding Forward-Looking Statements This presentation contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements regarding AngioDynamics’ expected future financial positi

  3. Slide 3: AngioDynamics

    AngioDynamics We are a dynamic, diversified medical technology company committed to expanding treatment options and improving patient outcomes and quality of life by focusing on cardiovascular disease and cancer. Our execution strategy is built on innovative R&D, clinical and regulatory pathway expa

  4. Slide 4: AngioDynamics Summary

    AngioDynamics Summary AngioDynamics Summary 4

  5. Slide 5: AngioDynamics Cardiovascular Portfolio

    Venous Thromboembolism (VTE) $5.3B US TAM* AngioDynamics Cardiovascular Portfolio Differentiated technologies and a comprehensive portfolio enable us to be a strong competitor within high growth Cardiovascular Disease market Cardiovascular Disease Cancer MINI STICK MAX Prostate Care $780M US TAM* Pe

  6. Slide 6: AngioDynamics MedTech Revenue Contribution

    AngioDynamics MedTech Revenue Contribution ~15% ~45% FY2021 $3.0B FY2023 $6.0B FY2025 $10.0B FY2018 $1.3B Total Addressable Markets Our demonstrated successful execution in portfolio optimization, clinical and regulatory expansion, and product introductions drives growth… Med TechGrowth Cardiovascul

  7. Slide 7: Venous Arterial

    VENOUS ARTERIAL 7

  8. Slide 8: Cardiovascular Arterial: Auryon Atherectomy System

    Cardiovascular Arterial With over 100,000 patients treated,6 the Auryon Atherectomy System is projected in FY25 to exceed cumulative sales of $180M since its September 2020 launch 7 Served $500M M A R K E T D Y N A M I C S Auryon ~10%+ ABT 38% BSX 6% PHG 15% MDT 31% ANGO 10% Treat all levels of calc

  9. Slide 9: Peripheral Artery Disease (PAD)

    P E R I P H E R A L A R T E R Y D I S E A S E (PAD) Aspiration capability and indicated for ISR and to aspirate thrombus adjacent to stenosis Intuitive, Windows-based touch screen Small and portable (29 in x 13 in x 37 in) Lightweight (198.45 lbs.) 110 V power outlet No calibration and minimal warm

  10. Slide 10: Auryon Platform Technology

    Auryon Platform Technology The Auryon System is designed to deliver an optimized wavelength, pulse width, and amplitude to remove lesions while preserving vessel wall endothelium10,11,14 Wavelength (nm) The distance between 2 successive waves determines absorption rate and penetration depth Pulse wi

  11. Slide 11: Auryon Platform Technology: Dual Method of Action

    Auryon Platform Technology The Auryon System’s dual method of action: Micro-CT Study21 Intimal Plaque/Calcium Debulking Works on removing different plaque morphologies, ATK – BTK and ISR Plaque/Calcium Modification Photomechanical shockwaves penetrate the medial wall to crack/modify plaque to bring

  12. Slide 12: Auryon Platform Technology: Expansion into Coronary Artery Disease

    Patient Enrollment Beginning Q2 CY 2025 RCT: 224 Patients Registry: ~1,500 Patients Initial European Experience in Coronary Artery Disease Auryon Platform Technology The Auryon System's technology has demonstrated safety and efficacy in PAD and presents an opportunity to expand into additional disea

  13. Slide 13: Venous Arterial: AngioVac and AlphaVac Indications

    VENOUS ARTERIAL The AngioVac Cannula is indicated for use as a venous drainage cannula and for removal of fresh, soft thrombi or emboli during extracorporeal bypass for up to 6 hours. The AlphaVac cannula is indicated for the non-surgical removal of thrombi or emboli and aspiration of contrast media

  14. Slide 14: Cardiovascular Venous

    Cardiovascular Venous Venous Thromboembolism (VTE) represents an attractive, high growth, underpenetrated market opportunity TAM $6B PE $3B DVT $3B Right Heart $120M Deep Vein Thrombosis (DVT) Mechanical Thrombectomy is estimated to have penetrated ~15% of the TAM 22 Mechanical Thrombectomy is expec

  15. Slide 15: AngioVac and AlphaVac Systems

    The AngioVac System allows for the continuous aspiration of embolic material such as thrombi and emboli from the venous system while simultaneously reinfusing the patient’s own filtered blood to limit procedural blood loss. MULTIPLE TIP ANGLES 200, 850, 1800 Proprietary Funnel Design Allows for Sign

  16. Slide 16: AngioVac Technology

    AngioVac Technology The only system that enables continuous aspiration and simultaneous reinfusion of blood, empowering physicians to treat more complex cases using minimally invasive techniques Aspiration & Simultaneous Reinfusion Proprietary Funnel On-circuit aspiration provides surgical results v

  17. Slide 17: AngioVac Clot Removal Procedure Results

    Actual procedure results, these images represent the experience of one institution and are not indicative of all procedural results. Clot Removal 30 min. *Dr. Keeling is a paid consultant of AngioDynamics EMORY HOSPITAL – MIDTOWNDr. Brent Keeling* (CT) 17

  18. Slide 18: AlphaVac Technology

    AlphaVac Technology Handle & Control Features MALE AND FEMALE CONNECTION Ensures correct connection SYRINGE BARREL VOLUME LIMITING SWITCH Intuitive location | Multiple glove sizes DURABLE LABELS Visible in low light environments VACUUM LOCK Controlled, single-hand design ANGLED HILT Easy access to v

  19. Slide 19: Advanced - Large Bore Aspiration

    Advanced - Large Bore Aspiration CANNULA Proprietary FUNNEL Manual Aspiration HANDLE Complete SYSTEM IU HEALTHDr. Thomas Casciani (IR) & Dr. Sabah Butty* (IR) *Dr. Butty is a paid consultant of AngioDynamics Actual procedure results, these images represent the experience of one institution and are n

  20. Slide 20: Pulmonary Embolism Indication

    Pulmonary Embolism Indication Study Approval March 2022 Enrolling October 2022 Enrollment Complete December 2023 Study Complete January 2024 CE Mark Approval May 2024 FDA Clearance AlphaVac F1885 for PE April 2024 Publication of APEX-AV Trial Results in JSCAI January 2025 20 Only the AlphaVac F1885

  21. Slide 21: APEX-AV Pivotal Study

    APEX – AV Pivotal Study 21 Number of Sites 25 US Sites Number of Patients 122 Timeline Oct. 2022 – Dec 2023 APEX (AlphaVac) FLARE (FlowTriever ) EXTRACT-PE28 (Indigo) Reduction in Clot Burden 35.5% 9.3% 11.3% AlphaVac F1885 received FDA clearance for PE following APEX-AV study demonstrating efficacy

  22. Slide 22: AngioDynamics Summary

    AngioDynamics Summary Our Med Tech segment operates in key markets with unique technologies that deliver proven clinical outcomes We have a strong track record in portfolio management, R&D, clinical and regulatory expansion, and customer-centric sales & marketing Our Med Device segment funds investm

  23. Slide 23: Shaping the Future of Cardiovascular Care

    Shaping the Future of Cardiovascular Care: Innovative Technologies. Improved Outcomes. INVESTOR EVENT

  24. Slide 24: References

    References FULL RISK INFO: https://www.angiodynamics.com/about-us/risk-information Management estimates & industry sources https://pmc.ncbi.nlm.nih.gov/articles/PMC10809869/#:~:text=Cardiovascular%20diseases%20have%20remained%20the,recorded%20in%202021%20%5B1%5D. https://pmc.ncbi.nlm.nih.gov/article

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