Pacific Biosciences Of California, Inc. · NASDAQ:PACB

Pacific Biosciences Of California — Q2 2026 Earnings Presentation

17 slides from Pacific Biosciences Of California's earnings presentation, Aug 5, 2026

  1. Slide 1: Q2 2026 Earnings Presentation

    Q2 2026 Earnings Presentation August 5, 2026 1

  2. Slide 2: Safe harbor and non-GAAP disclosures

    Safe harbor and non-GAAP disclosures Statement regarding use of non‐GAAP financial measures PacBio reports non‐GAAP results for basic net income and loss per share, net income, net loss, gross margins, gross profit (loss), and operating expenses in addition to, and not as a substitute for, or becaus

  3. Slide 3: Positioning PacBio for the Next Phase of Growth

    Positioning PacBio for the Next Phase of Growth Mark Van Oene President and Chief Executive Officer • Five years as PacBio's Chief Operating Officer • Led R&D, Operations and Commercial organizations • Drove Revio, Vega and SPRQ-Nx development • Deep knowledge of PacBio and the genomics and clinical

  4. Slide 4: Q2 2026 Summary

    Q2 2026 Summary $39.0M $12.8M Instrument Revenue Total Revenue 20 Revio Systems 26 Vega Systems ~60% to new customers ~80% to new customers $20.1M Consumable Revenue Cumulative Revio and Vega Shipments • Record clinical & hospital sales • ~$202,000 annualized Revio pull- through 4

  5. Slide 5: Q2 2026 revenue breakdown

    Q2 2026 revenue breakdown Product & Service Regional Asia Pacific $7.0M Consumables $20.1M Instruments Americas $12.8M $39.0M $17.6M $39.0M EMEA $14.4M Service + Other $6.1M 5

  6. Slide 6: SPRQ-Nx is designed to deliver high-quality HiFi at a highly competitive price point

    SPRQ-Nx is designed to deliver high-quality HiFi at a highly competitive price point Executed full launch in Designed to deliver among the most complete view of the genome with U.S list price of $345 per genome May 2026 Multi-use SMRT cells One-third of install base opted Intended to reduce the cost

  7. Slide 7: New publications highlight growing validation of our differentiated technology

    New publications highlight growing validation of our differentiated technology Recent publication in Article entitled “Clinical Long-Read Genome Sequencing for Rare-Disease Diagnostics” proves HiFi improves diagnostic NEJM demonstrates HiFi yield while also simplifying the laboratory workflow, as a

  8. Slide 8: HiFi Solves Sub-fertility Consortium releases preprint from first major study in Asia Pacific

    HiFi Solves Sub-fertility Consortium releases preprint from first major study in Asia Pacific ✓ Multinational study investigating unexplained subfertility and recurrent pregnancy loss ✓ Comprehensive genomic workflow and secure data collaboration may help reduce fragmented testing for couples seekin

  9. Slide 9: Q2 2026 non-GAAP financial highlights

    Q2 2026 non-GAAP financial highlights Non-GAAP1 Measures Q2 2026 Q2 2025 Non-GAAP Gross Profit $13.9M $15.2M Non-GAAP Gross Margin 36% 38% Non-GAAP Operating Expenses $56.1M $58.1M Non-GAAP Net Loss $41.9M $40.0M Non-GAAP Basic Net Loss Per Share $0.14 $0.13 December 31, June 30, 2026 March 31, 2026

  10. Slide 10: Updating 2026 guidance

    Updating 2026 guidance Revenue $155M - $165M (3%) - +3% y/y growth Non-GAAP Gross Margin Non-GAAP Operating Expenses 35% - 37% $215M - $220M vs. 40% in 2025 vs. $230M in 2025 10

  11. Slide 11: 2026 focus areas

    2026 focus areas Dramatically improve the economics of HiFi through SPRQ-Nx with multi-use SMRT cells Accelerate clinical adoption across rare disease, oncology, and carrier screening Enable discovery through large-scale studies with HiFi’s rich data and high-throughput capabilities Empower next-gen

  12. Slide 12: Enabling the promise of genomics to better human health

    Our mission Enabling the promise of genomics to better human health Creating the world’s most advanced sequencing technologies 12

  13. Slide 13: Appendix

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  14. Slide 14: Condensed Consolidated Statements of Operations

    PacBi@ @ excep per share amounts) i : : | | Service and other revenue 6057 sos4 683 Cost of Revenue: Cost of service and other revenue 5242 482 3 8 ‘Loss on purchase commitment ' ' 2 Gross profit i 3 A Research and development E i i Settlement charges!” ' z 3 ' ‘Amortization of acquired intangible a

  15. Slide 15: Unaudited Condensed Consolidated Balance Sheets

    PacBi@ Pacific Biosciences of California, Inc. Unaudited Condensed Consolidated Balance Sheets June 30, December 31, (in thousands) 2026 3 Accounts receivable, net 31,104 i Prepaid expenses and other current assets © E 10,793 Operating lease right-of-use assets, net 40,331 41,695 Intangible assets,

  16. Slide 16: Non-GAAP reconciliation

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  17. Slide 17: www.pacb.com

    www.pacb.com Research use only. Not for use in diagnostic procedures. © 2024 Pacific Biosciences of California, Inc. (“PacBio”). All rights reserved. Information in this document is subject to change without notice. PacBio assumes no responsibility for any errors or omissions in this document. Certa

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