Gsk Plc · LSE:GSK
Gsk — Technical Presentation (July 2017)
13 slides from Gsk's technical presentation, July 2017
Slide 1: GSK High Containment Capability
GSK Conk fle righ ‘Comtaimmentye Capability ee ff We specialise in the Development, Launch and Manufacture of complex and difficult APIs, including your requirements for High Containment and Particle Characterisation
Slide 2: Doing Business in Ireland
DOING BUSINESS IN IRELAND • Ireland’s corporation tax rate of 12.5% is amongst the lowest in the world and compares very favourably with other countries • Ireland also has a favourable holding company regime and is an attractive location to establish corporate support / hub activities • A 25% tax cr
Slide 3: do more, feel better, live longer
do more feel better live longer
Slide 4: GSK Cork - High Containment Capability
GSK Cork - High Containment Capability GSK Cork has over 17 years experience in the manufacture of High Containment products. The site had 2 high containment buildings •Building 5 is a state of the art small scale facility (commissioned in 2007) designed for the handling , manufacture and testing of
Slide 5: GSK Cork - Technical Transfer Capability
GSK Cork –Technical Transfer Capability GSK Cork has extensive experience in the introduction of New Chemical Entities (NCE) from R&D Recently Cork has completed 3 business opportunities transfers. The experience from the NCE transfers has enhanced key attributes of a process against previous perfor
Slide 6: Small Scale High Containment Plant - Building 5
Small Scale High Containment Plant - Building 5 Building 5 • A small scale multipurpose processing plant for API’s and Intermediate stages • OHC 5(< 1mg/m3) capability and highly �lexible processing module • < 30 nanograms/m3 demonstrated • 6 Gloveboxes • Dedicated development & QC analytical labora
Slide 7: Small Scale High Containment Plant - Building 5 Processing Equipment
Small Scale High Containment Plant - Building 5 Processing Equipment 3 x Gloveboxes and 2 x fumehoods GMP QC Analytical Lab Dispensing + Utilities area Solvent Charging fumehood (pressure kettles) Area Development Lab Building 5 Vent to Inert Header via HEPA filter GB-1 316L SS Upper Level 1 x gaf G
Slide 8: Material Charging - Building 5
Material Dispensing- Material Charging- BLD 5 BLD 5
Slide 9: Laboratory - Building 5
Primary Processing High Containment Area- BLD 5 Laboratory- BLD 5
Slide 10: Medium Scale High Containment Plant - Building 8
Medium Scale High Containment Plant - Building 8 •A small to medium scale multipurpose processing plant for API •OHC 5 (< 1mg/m 3) containment for charging and offload •4 Glass Lined reactor vessels •20L to 400L scale of wet end processing •Dedicated scrubber •1 Hastelloy Filter Dryer (0.3m 2) •1 So
Slide 11: Building 8 Processing Equipment
Small Scale High Containment Plant - Building 8 Processing Equipment M M HTK 1 HTK 2 SS PFA Lined SS 20L 120L Venting available to RV-1 RV-2 GB1 scrubber & incinerator M 250L M GLCS GLCS 250L Bulk Solvents: Fume Hood for odorous Pressure Charging Kettle 2nd Floor Charging GB2 M RV3 M RV4 1st Floor M
Slide 12: Material Dispensing and Charging - Building 8
Material Dispensing- Material MaterialBLD 5 Charging- Dispensing- BLD 8 BLD 8
Slide 13: Laboratory - Building 8
Primary Processing High Containment Area- BLD 8 Laboratory- BLB 8