Atricure, Inc. · NASDAQ:ATRC

Atricure — Q4 2024 Earnings Presentation

22 slides from Atricure's earnings presentation, Feb 12, 2025

  1. Slide 1: Creating a World Class Platform

    Creating a World Class Platform Investor Presentation February 2025 © 2025 AtriCure, Inc. All rights reserved.

  2. Slide 2: Forward Looking Statements and Non-GAAP Financial Measures

    Forward Looking Statements and Non-GAAP Financial Measures This presentation and oral statements made in connection with this presentation contain “forward-looking statements,” which are statements related to future events that by their nature address matters that are uncertain. Forward-looking stat

  3. Slide 3: We are passionately focused on healing the lives of those affected by Afib and pain

    We are Large Markets Addressing an underserved and passionately growing patient population focused on Strong Portfolio healing the lives Existing products and solutions and continuous innovation driving of those affected consistent growth by Afib and pain Bright Future after surgery Novel therapies

  4. Slide 4: Strategic Focus

    Strategic Focus Profitable Expansion Growth Clinical Innovation Science Developing Strong history of addressable markets revenue growth and Continuous Differentiated clinical and expanding acceleration from improvement, trials with superior patient impact multiple catalysts with increasing pipeline

  5. Slide 5: Afib: A Serious Problem

    Afib: A Serious Problem Atrial Fibrillation (Afib) is an 5x Higher Risk of Stroke1 irregular heartbeat (or arrhythmia) tied to higher risk of stroke, heart 5x Greater Risk of All-Cause Death1 failure, dementia, and other health problems >5x Higher Risk of Heart Failure2 © 2025 AtriCure, Inc. All rig

  6. Slide 6: Afib: A Serious Problem

    Afib: A Serious Problem Afib affects more than 59 million people worldwide. 3 1 in 4 Adults > 4 Million Over the age of 40 People estimated to have will develop Afib in their long-standing persistent Afib lifetime4 in the US5 © 2025 AtriCure, Inc. All rights reserved. 6

  7. Slide 7: AtriCure Patient Profile

    AtriCure Patient Profile Differentiated Focus: Creating Standards of Care for Patients with Advanced Afib and Managing Post-Operative Pain Afib Pain Management Structural Heart Issue No Structural Issue Thoracic Surgery Surgery required (Valve, CABG) Afib is primary concern Intercostal nerve pain Af

  8. Slide 8: Significant Global Market Opportunity

    Significant Global Market Opportunity $5B+ Current Global Opportunity $1B 2010 Global Pain Opportunity Management Ablation Thoracic Procedures Hybrid Cardiac Therapy Surgery MIS Ablation + Open Ablation + LAAM LAAM Cardiac Surgery Standalone Treatment Concomitant for Long-Standing Treatment Pre-Op A

  9. Slide 9: Expanding Market Opportunity

    Expanding Market Opportunity $10B+ Global Opportunity Leading with innovation, clinical science and education to establish and grow our markets Pain Pain Pain Management Management Management Ablation Ablation + Ablation Extremities Thoracic Procedures Hybrid Sternotomy Procedures Therapy Hybrid The

  10. Slide 10: Innovation and Clinical Milestones

    Innovation and Clinical Milestones 2000 2010 2015 2020 • AtriCure • Isolator® Synergy • EPi-Sense® • EPi-Sense System approved by FDA for founded Ablation System FDA system acquired treatment of long-standing persistent Afib approved for treatment • First patient of persistent or long- • AtriClip PR

  11. Slide 11: Treatment of Afib and LAAM

    Treatment of Afib and LAAM Guidelines for Clinical Practice Lasts beyond 7 days Lasts longer than 1 year and as long as 1 year without stopping Sources included in Appendix © 2025 AtriCure, Inc. All rights reserved. 11

  12. Slide 12: Treatment of Afib and LAAM: Improving Access through Reimbursement

    Treatment of Afib and LAAM Improving Access through Reimbursement Hospital Reimbursement MS-DRG 317 Hospital Reimbursement Epicardial Ablation + MS-DRG 212 Lasts longer than 1 year Physician Reimbursement Epicardial LAA CPT 33267, 33268, 33269 AVR + MVR + Surgical without stopping Ablation $15k - $2

  13. Slide 13: Cardiac Surgery Ablation + LAAM

    Cardiac Surgery Ablation + LAAM Established Market and Advancing Innovation in Patient Care Key Initiatives and Growth Drivers • Penetrate global market with EnCompass  Approved. Isolator Synergy clamp Ablation System first medical device with FDA approval for treatment of Afib • Drive adoption of

  14. Slide 14: Hybrid Therapy Ablation + LAAM

    Hybrid Therapy Ablation + LAAM Growing Market with Unique Solutions for Advanced Afib Patients Key Initiatives and Growth Drivers >4 Million • Drive adoption of Hybrid AF Therapy with Epi-Sense / ST devices, expanding global People estimated to have long- customer base standing persistent Afib in th

  15. Slide 15: Pain Management

    Pain Management Leading Market Development through Ablation Expertise Key Initiatives and Growth Drivers • Expand adoption of 2024 new product launches: cryoSPHERE+ probe and cryoSPHERE MAX probe Cryo Nerve Block Therapy • Reduced freeze times by 25% can be an important tool in (cryoSPHERE+) and 50%

  16. Slide 16: Fourth Quarter 2024 Financial Highlights

    Fourth Quarter 2024 Financial Highlights Worldwide Revenue* ($M) Key Metrics* +16.7% $124.3 Q4 2024 Q4 2023 GROSS MARGIN 74.5% 74.9% $115.9 +7.2% OPERATING EXPENSES $107.1M $88.5M ADJUSTED EBITDA+ $12.7M $4.8M $106.5 ADJUSTED LOSS PER SHARE+ ($0.08) ($0.21) CASH & INVESTMENTS $123M $137M Q4 2023 Q3

  17. Slide 17: 2024 Highlights and Accomplishments

    2024 Highlights and Accomplishments 17% Top Workplace Honors Annual Fast Company’s Cincinnati, Minneapolis, Netherlands, Revenue 100 Best Workplaces Australia, United Kingdom Growth for Innovators 26% cryoS+ Key New cryoS ATRICLIP Product Launches MAX FLEX•Mini 4,200 International Pain Management LA

  18. Slide 18: Financial Results and 2025 Outlook

    Financial Results and 2025 Outlook $500 +17% $450 $400 +21% $350 Worldwide Revenue +20% $300 $250 +33% 2025 Guidance $200 Worldwide Revenue $150 $517 million to $527 million $100 Adjusted EBITDA $50 $42 million to $44 million $- ($ Millions) 2020 2021 2022 2023 2024 Modest Cash Flow Generation $40 S

  19. Slide 19: Key Takeaways

    Key Takeaways Strong Q4 2024 and FY 2024 2025 Guidance Worldwide Revenue Q4 Worldwide Revenue $517M to $527M $124.3M (~17% Growth) Adjusted EBITDA 2024 Worldwide Revenue $42M to $44M $465.3M (~17% Growth) Positive Cash Flow 2024 Adjusted EBITDA $31.1M (~60% Increase) Focused on Market Analyst & Pene

  20. Slide 20: Thank You!

    Thank You! © 2025 AtriCure, Inc. All rights reserved.

  21. Slide 21: References and Abbreviations

    References and Abbreviations Key Abbreviations Afib or AF Atrial Fibrillation Note Reference AVR Aortic Valve Repair/Replacement Odutayo, A. et al. (2016). Atrial fibrillation and risks of cardiovascular disease, renal disease, and deaths systematic review and meta 1 analysis. BMJ 2016; 354:i4482 CA

  22. Slide 22: Sources Tables

    Sources Tables Treatment of Afib and LAAM Treatment of Afib and LAAM Advancing Guidelines for Clinical Practice Improving Access through Reimbursement Sources: January, C. T., Wann, L. S., Calkins, H., Chen, L. Y., Cigarroa, J. E., Cleveland Jr, J. C., ... & Sources: In 2021, CMS moved CABG plus abl

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