Pfizer, Inc. · NYSE:PFE

Pfizer — Citi Investment Research Global Health Care Conference 2008

23 slides from Pfizer's conference presentation, May 21, 2008

  1. Slide 1: Citi Investment Research Global Health Care Conference

    Citi Investment Research Global Health Care Conference Frank D’Amelio Chief Financial Officer May 21, 2008

  2. Slide 2: Forward-Looking Statements and Non-GAAP Financial Information

    Forward-Looking Statements and Non-GAAP Financial Information „ Discussions at this meeting will include forward-looking statements. Actual results could differ materially from those projected in the forward- looking statements. The factors that could cause actual results to differ are discussed in

  3. Slide 3: Our Path Forward

    Our Path Forward Maximize Revenues from Existing, New & Diverse Sources ƒ Take Advantage of Size, Scale of Pfizer Establish a Lower, More Flexible Cost Base ƒ Operate with Agility, Speed, Focus of an Entrepreneurial Organization Innovate our Business Model Drive Greater Total Shareholder Return

  4. Slide 4: Our Path Forward: Strategies for Growth

    Our Path Forward: Strategies for Growth US Lipitor Post Today LOE Lipitor Optimize the Patent-Protected Portfolio Š Maximize the Value of New and Inline Products Š Advance Compounds in the Pipeline Maximize Revenues Capitalize on Established Products Sustainable TSR Growth Grow in Emerging Markets „

  5. Slide 5: Optimize the Patent-Protected Portfolio

    Optimize the Patent-Protected Portfolio Maximize Revenues

  6. Slide 6: First Quarter 2008 Select Product Highlights

    First Quarter 2008 Select Product Highlights ($ millions) Worldwide U.S. International 2008 Change 2008 Change 2008 Change In-Line Products(1) Lipitor $3,137 (7%) $1,751 (18%) $1,386 13% Viagra 460 6% 223 (1%) 237 13% Celebrex 611 2% 464 (2%) 147 20% Lyrica 582 47% 351 45% 231 51% Xalatan/Xalacom 40

  7. Slide 7: Optimize the Patent-Protected Portfolio: Maximize New and In-Line Products

    Optimize the Patent-Protected Portfolio: Maximize New and In-Line Products +86% +71% „ Launched 62 countries „ Launched 56 countries; expect 20+ in „ >90% coverage of U.S. third party next 12 months payers „ Used by 6 million smokers globally „ Phase 3 trials in breast, lung, colorectal; „ Refill ra

  8. Slide 8: Optimize the Patent-Protected Portfolio: Advance Compounds in the Pipeline

    Optimize the Patent-Protected Portfolio: Advance Compounds in the Pipeline Pipeline as of Feb 28, 2008 Approved More than Selzentry 300 Phase 1 Phase 2 Phase 3 In Reg. Lyrica for Discovery 47 37 16 2 Fibromyalgia Projects fesoterodine (EU) (Pipeline as of July 31, 2007) 38 47 11 3 Goals „ 15–20 Phas

  9. Slide 9: Optimize the Patent-Protected Portfolio: Disease Area Priorities

    Optimize the Patent-Protected Portfolio: Disease Area Priorities Invest to Win First or High Market High Best in Class Growth Unmet Need 9 9 9 „ Oncology „ Pain „ Immunology / Inflammation „ Diabetes / Obesity „ Alzheimer’s Disease „ Schizophrenia Maximize Revenues

  10. Slide 10: Optimize the Patent-Protected Portfolio: Oncology

    Optimize the Patent-Protected Portfolio: Oncology The Current Opportunity „ Opportunity by 2012: = $57.3 B Š $81 B Š 7% CAGR Pfizer $2.6 B „ Pfizer Assets and Advantages: 4% PreClin Phase I Phase II Phase III Market 5 13 6 5 5 „ Pfizer Strategy: Š Established Worldwide Oncology Business Unit; recent

  11. Slide 11: Capitalize on Established Products

    Capitalize on Established Products „ Opportunity by 2012: The Current Opportunity = $271 B Š $523 B Š 11% CAGR Pfizer „ Pfizer Assets and Advantages: $12 B Š Excellent portfolio of products 4% Š Strong brand recognition for innovation, quality and safety Š Cutting-edge manufacturing technology Š Bro

  12. Slide 12: The Market Is Not Homogenous, Three Distinct Market Segments

    The Market Is Not Homogenous, Three Distinct Market Segments Dispensing Drivers: Payers and Pharmacy Channel, with Physician Branded Emerging Markets and Pharmacy Influence Branded Traditional Markets IP-Driven Markets „ Brand: Moderately Important „ 2012 Size: $130B „ LOE Cliff: Moderate Dispensing

  13. Slide 13: Grow in Emerging Markets

    Grow in Emerging Markets „ Opportunity by 2011: The Current Opportunity Š $225 B = $149 B Š 11% CAGR Pfizer „ Pfizer Assets and Advantages: $5 B Š Ability to leverage global scale, 3% product breadth and growing oncology portfolio Š Increasing R&D focus, including R&D incubator and Asian investment

  14. Slide 14: The Emerging Asian Markets Opportunity

    The Emerging Asian Markets Opportunity Today 2012 Projection 2017 Projection 7–9% 6% 4% $47B $79B $111B Market Pfizer Source: Projections based upon IMS Market Prognosis March 2007 & Internal Analysis (excludes Japan, Australia, New Zealand) Maximize Revenues

  15. Slide 15: Why Pfizer Expects to Succeed in Established Products and Emerging Markets

    Why Pfizer Expects to Succeed in Established Products and Emerging Markets Pfizer has Unique Competitive Advantages „ Large Diversified Portfolio „ Tremendous Brand Recognition for Quality „ Strong Presence in the Right Geographies „ Experienced Local Talent Close to the Operations Maximize Revenues

  16. Slide 16: Proven Track Record of Managing Costs

    Proven Track Record of Managing Costs 12/31/04(1) 3/30/08 Change Manufacturing Sites 78 57 (27%) Outsourced Manufacturing (%) 9% 17% 8 pts. R&D Sites 15 10 (33%) Total Real Estate Sq. Footage 80 54 (33%) (in millions) Sales Force 36,300 28,000 (23%) Total Headcount 110,000(2) 85,000 (23%) (1) In the

  17. Slide 17: Plans for Continued Cost Management

    Plans for Continued Cost Management Manufacturing Research and Development „ Increasing outsourced manufacturing to „ Utilizing Enhanced Clinical Trial Design 30%, while maintaining quality „ Applying Biotech Investment Paradigm „ Reducing network of manufacturing plants „ Using Centers of Emphasis

  18. Slide 18: Innovate the Business Model: Pharmaceutical Operations

    Innovate the Business Model: Pharmaceutical Operations Change Benefits Realized „ Reduced the field force by about 20% „ Launched Lyrica fibromyalgia indication 2 months 5 U.S. Business earlier than would have been done under the prior Units model „ Formation of highly-trained, razor sharp field for

  19. Slide 19: Innovate the Business Model: Research and Development

    Innovate the Business Model: Research and Development Change Benefits Realized „ Instituted „ Accelerated 20 high value programs and terminated 23 New programs Compound Review „ Identified 6 key disease areas to ‘Invest to Win’ Process „ Initiated Phase 3 starts of the following: „ Moved to Š IGF-1R

  20. Slide 20: 2008 Financial Guidance

    2008 Financial Guidance Guidance(3) Revenues $47.0 to $49.0 Billion Decrease of at least $1.5–$2 Billion Adjusted Total Costs(1) versus 2006 on a constant currency basis(2) Adjusted Cost of Sales(1) as a 14.5% to 15.5% Percentage of Revenue Adjusted R&D Expenses(1) $7.3 to $7.6 Billion Adjusted SI&A

  21. Slide 21: Cash Flow from Operations

    Cash Flow from Operations ($ billions) $17.6 $17.0 to $18.0 $14.7 $13.4 2005 2006 2007 2008 Guidance Continued Strong Cash Flow from Operations Financial Metrics

  22. Slide 22: Our Path Forward

    Our Path Forward Maximize Revenues from Existing, New & Diverse Sources ƒ Take Advantage of Size, Scale of Pfizer Establish a Lower, More Flexible Cost Base ƒ Operate with Agility, Speed, Focus of an Entrepreneurial Organization Innovate the Business Model Drive Greater Total Shareholder Return

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