Qiagen N.v. · NYSE:QGEN

Qiagen — Virtual Commerzbank/Oddo BHF Corporate Conference 2021

101 slides from Qiagen's conference presentation, Sep 22, 2021

  1. Slide 1: Investor Handout

    Investor Handout QIAGEN: A stronger company set for solid post-pandemic growth Q3 2021 Sample to Insight

  2. Slide 2: Forward looking and intended use statements

    Forward looking and intended use statements Safe Harbor Statement: This presentation contains both historical and forward-looking competitors' products; market acceptance of QIAGEN's new products and the integration of statements. All statements other than statements of historical fact are, or may b

  3. Slide 3: Table of Contents

    Table of Contents About QIAGEN 4 Sustainability 51 • QIAGEN at a glance 4 • Environmental 54 • Global presence 6 • Social 57 • Customers 7 • Governance / Leadership 61 • Sales and EPS performance 10 • Strategy 11 Full results Q2 2021 69 Product portfolios 15 • Sample technologies 17 • Diagnostic sol

  4. Slide 4: QIAGEN at a glance

    QIAGEN at a glance 2020 sales Global sales reach $1.8 bn 44% Americas 48% 52% 37% EMEA 19% Asia-Pacific / Japan Molecular Life Diagnostics Sciences >5,600 employees 86% 14% Innovative cutting-edge portfolios worldwide Consumables Instruments and related revenues • Trusted brand known for quality and

  5. Slide 5: Comprehensive portfolio to help our customers unlock valuable molecular insights

    Comprehensive portfolio to help our customers unlock valuable molecular insights Sample technologies Assay technologies Advancing understanding of life Faster and better drug R&D Better diagnoses Sample to Insight solutions Ensuring public safety Automation systems Bioinformatics VALUABLE BIOLOGICAL

  6. Slide 6: Our global presence: Focused on the most attractive developed and emerging markets

    Our global presence: Focused on the most attractive developed and emerging markets Sollentuna Venlo Aarhus Distribution Manchester Wroclaw Toronto Beverly Hilden partners Paris Milan Seoul Barcelona Ankara Beijing Tokyo in >60 Redwood City Germantown / Cairo New Delhi countries Shanghai Frederick Du

  7. Slide 7: Our Customers: Addressing the world's most pressing challenges

    Our Customers: Addressing the world’s most pressing challenges >500,000 customers benefiting from the value of molecular insights Life Sciences Academia How can we achieve scientific breakthroughs even faster? Pharma How can we develop better and safer drugs? Applied Testing How can we improve publi

  8. Slide 8: Life Sciences: Enabling the advancement of science with differentiated technologies

    Life Sciences: Enabling the advancement of science with differentiated technologies Academia ~$5 billion QIAGEN value addressable market • 2020 sales of ~$966 million ~5-6% CER • Recognized innovator supporting breakthrough science Pharma market growth • Ability to translate innovations into commerc

  9. Slide 9: Molecular Diagnostics: Improving outcomes for patients and increasing lab efficiencies

    Molecular Diagnostics: Improving outcomes for patients and increasing lab efficiencies ~$6 billion addressable QIAGEN value market • 2020 sales of ~$904 million • Focused on high-growth, high-demand opportunities Molecular ~6-7% CER Diagnostics market growth(1) • Strong automation portfolio expansio

  10. Slide 10: Strong foundation for solid and sustainable CER sales growth from non-COVID products

    Strong foundation for solid and sustainable CER sales growth from non-COVID products Annual sales trends Adjusted diluted EPS trends In $ billion In $ per share ≥12% CER ≥ $2.42 CER $1.8 $2.15 $1.5 $1.5 $1.4 $1.3 $1.43 $1.34 $1.27 $1.11 2016 2017 2018 2019 2020 2021 2016 2017 2018 2019 2020 2021 out

  11. Slide 11: Our strategy: Unwavering focus on five pillars of growth

    Our strategy: Unwavering focus on five pillars of growth 2019: 2020 and beyond: Pursuing a broad range of opportunities Sharpened focus on five pillars of growth Portfolio with multiple new launches – but diluted efforts Ability to take top 3 leadership position with waves of organic growth Sample Q

  12. Slide 12: Pillars of growth supported by differentiated core portfolios

    Pillars of growth supported by differentiated core portfolios Five pillars of growth Sample QIAcuity QIAstat-Dx NeuMoDx QuantiFERON technologies Pillars of growth supported by core business Core business Genomics / NGS Precision PCR / Nucleic acid Human ID / QIAGEN OEM Medicine amplification Forensi

  13. Slide 13: Five pillars targeting >$6 billion opportunities of our $11 billion total addressable market

    Five pillars targeting >$6 billion opportunities of our $11 billion total addressable market Sample technologies QIAcuity QIAstat-Dx NeuMoDx QuantiFERON Strengthen excellence in Enter digital PCR Accelerate Fully integrate Extend leadership in Sample technologies market with QIAcuity QIAstat-Dx adop

  14. Slide 14: Investing to drive further waves of growth in five pillars

    Investing to drive further waves of growth in five pillars Executing on a roadmap to fuel robust growth beyond 2021 Q2 2021 status 2021 plan 2022 plan 2023 and beyond Sample Broadest portfolio with • New automation workflows • New applications • Next generation platforms technologies leading brand r

  15. Slide 15: QIAGEN product portfolios

    QIAGEN product portfolios Sample to Insight

  16. Slide 16: Reporting sales in product groups

    Reporting sales in product groups Five pillars of growth Sample QIAcuity QIAstat-Dx NeuMoDx QuantiFERON QIAGEN product groups technologies(1) digital PCR(3) Sample technologies(1) Consumables and instruments used in sample collection, stabilization, storage, purification and quality control includin

  17. Slide 17: Sample technologies

    Sample collection, stabilization Manual sample preparation and storage solutions Sample technologies Customers Automated sample preparation Quality control instruments Life Sciences Molecular Diagnostics Sample to Insight Investor handout - Q3 2021 17

  18. Slide 18: The first step in virtually any molecular biology laboratory process

    Sample technologies The first step in virtually any molecular biology laboratory process QIAGEN holds leading products in the vast majority of applications mRNA microRNA Gel extraction Total RNA from FFPE tissue Post-reaction cleanup Total RNA from whole blood (i.e. PCR, enzyme digestion) ~70-75% of

  19. Slide 19: The solid foundation of the QIAGEN story

    Sample technologies The solid foundation of the QIAGEN story From a strong start with plasmid kits to a market leading portfolio for sample collection, stabilization and purification QIAGEN pioneered the nucleic All kits based on acid purification kit – Spin-column purification the same easy-to- rev

  20. Slide 20: Offering a full range of hands-free sample preparation automation

    Sample technologies Offering a full range of hands-free sample preparation automation Advanced platforms to automate QIAGEN sample technologies for low to high sample volumes QIAcube Connect QIAcube HT EZ1 / EZ2 QIAsymphony Automation option for QIAGEN 96-well plate format using the Automation with

  21. Slide 21: SPOTLIGHT: QIAsymphony – Flagship platform for sample processing

    Sample technologies SPOTLIGHT: QIAsymphony – Flagship platform for sample processing Off-the-shelf solutions and customizable protocols to fit wide range of laboratory needs • Over 400 new placements in 2020 • Front-end automation solution for molecular testing • Regionalization strategy ◦ US: Focus

  22. Slide 22: Diagnostic solutions

    Immune Response Infectious diseases Diagnostic solutions Oncology and Precision Medicine Women’s Health Customers Molecular Diagnostics Sample to Insight Investor handout - Q3 2021 22

  23. Slide 23: Immune Response: Best-in-class IGRA test for latent tuberculosis

    Diagnostic solutions Immune Response: Best-in-class IGRA test for latent tuburculosis What is QuantiFERON? QuantiFERON-TB Gold Plus (QFT-Plus) is a simple blood test that aids in the detection of Mycobacterium tuberculosis, the bacteria which causes tuberculosis (TB). Latent TB testing market QFT-Pl

  24. Slide 24: A growing market demand for modern latent TB testing

    Diagnostic solutions A growing market demand for modern latent TB testing What is the difference between latent TB and active TB? Latent TB infection (LTBI) can persist for weeks, months or years before ~70 million latent TB tests per year across the world developing into active disease. Although LT

  25. Slide 25: QuantiFERON offers fully automated workflows for low and high throughput testing

    Diagnostic solutions QuantiFERON offers fully automated workflows for low and high throughput testing Enabling hands-free processing of QFT-TB Gold Plus QuantiFERON differentiation Strong best-in-class market position DiaSorin Full automation capability • High performing assay: QFT TB Gold Plus (4th

  26. Slide 26: QuantiFERON Lyme: Combination of tests allowing a new level of detection

    Diagnostic solutions QuantiFERON Lyme: Combination of tests allowing a new level of detection CE-IVD test launched April 2021 Rising occurrence of Lyme disease Confirmed cases Potential testing market 40,000 Europe ~35,000 per year ~12-14 million tests per year U.S. ~30,000 per year ~5 million tests

  27. Slide 27: Infectious diseases: New generation of PCR technology for urgent needs

    Diagnostic solutions Infectious diseases: New generation of PCR technology for urgent needs Core / Hospital laboratories Near-patient clinical laboratories Hospital and Community hospitals and reference lab networks reference lab “outreach” centers Requirements: Requirements: Market opportunity Mark

  28. Slide 28: QIAstat-Dx: Capturing opportunities in the rapidly growing market of syndromic testing

    Diagnostic solutions QIAstat-Dx: Capturing opportunities in the rapidly growing market of syndromic testing What is syndromic testing? Syndromic testing is a new approach to molecular diagnostic testing which uses a single test to look for multiple viral, bacterial or fungal infections. Sets of comm

  29. Slide 29: QIAstat-Dx: Reliable, fast and cost-effective diagnosis of complex syndromes

    Diagnostic solutions QIAstat-Dx: Reliable, fast and cost-effective diagnosis of complex syndromes Unrivaled ease-of-use – no sample preparation required Liquid / solid sample input Dry swab sample input Self- contained cartridge Real-time PCR reaction chambers Analytical modules Operational module •

  30. Slide 30: QIAstat-Dx: Accelerated commercialization setting-up post-pandemic growth

    Diagnostic solutions QIAstat-Dx: Accelerated commercialization setting-up post-pandemic growth opportunities Menu expansion plans 2021 and beyond ambitions Completed CE-IVD • 2021 sales target: >$60 million THOMAS U.S. Submissions planned and completed NEW DESIGN FROM Gastrointestinal • Create broad

  31. Slide 31: QIAstat-Dx: Novel syndromic testing system delivering unique value

    Diagnostic solutions QIAstat-Dx: Novel syndromic testing system delivering unique value QIAstat-Dx Biofire FilmArray Biofire Torch Luminex ePlex Genmark Verigene (4 scalable slots (1 slot) (12 slots) (12 slots) (1 slot) Competitive benchmarking used for comparison) Throughput (in 8 hours) 28 9 108 6

  32. Slide 32: NeuMoDx: Bringing simplicity of clinical chemistry to integrated PCR testing

    Diagnostic solutions NeuMoDx: Bringing simplicity of clinical chemistry to integrated PCR testing New generation of integrated PCR NeuMoDx differentiation • Two scalable platforms: 96 and 288 • Easier: Three-step workflow process • Fully acquired in September 2020 • Faster: First results in ~1 hour

  33. Slide 33: NeuMoDx: Robust start on installed base build-out and accelerated menu expansion

    Diagnostic solutions NeuMoDx: Robust start on installed base build-out and accelerated menu expansion Menu expansion plans Status as of Q2 2022 2021 and beyond ambitions Submissions planned and completed CE-IVD U.S. • 2021 sales target: >$100 million HBV 2022 ◦ Implement agressive menu expansion pla

  34. Slide 34: NeuMoDx: A unique integrated PCR testing platform in >$3 billion market opportunity

    Diagnostic solutions NeuMoDx: A unique integrated PCR testing platform in >$3 billion market opportunity Competitive benchmarking Roche Cobas Hologic Hologic 6800 Roche Cobas Beckman Veris NeuMoDx 288 NeuMoDx 96 Panther Abott Alinity M Panther (+ Omni LDT 8800 (Discontinued) Fusion channel) Volume i

  35. Slide 35: Oncology and Precision Medicine: QIAGEN as a partner of choice

    Diagnostic solutions Oncology and Precision Medicine: QIAGEN as a partner of choice >25 pharma partnerships CDx and LDT Market >$1.1 billion annually >50 active development programs ~15% CAGR Currently mostly LDT’s 7 FDA approvals and 5 CE-IVD to date Day One Lab Readiness program Program designed t

  36. Slide 36: Oncology and Precision Medicine: QIAGEN as a partner of choice

    Diagnostic solutions Oncology and Precision Medicine: QIAGEN as a partner of choice QIAGEN molecular diagnostic development Offering both 26 IVD development programs either in pre-clinical or clinical phase PCR and NGS technologies 20 CDx (Pharma sponsored) programs in clinical development for CDx I

  37. Slide 37: Women's Health: Prenatal testing and detection of sexually transmitted diseases

    Diagnostic solutions Women’s Health: Prenatal testing and detection of sexually transmitted diseases Cervical cancer screening • Digene – Comprehensive range of human papillomavirus DNA test Maternal / Fetal testing • AmniSure – For the detection of PAMG-1 in amniotic fluid of pregnant women • Parto

  38. Slide 38: PCR / Nucleic Acid amplification

    Digital PCR - QIAcuity PCR reagents and instrumentation PCR / Nucleic Acid amplification Customized arrays Customers Life Sciences Sample to Insight Investor handout - Q3 2021 38

  39. Slide 39: PCR: One of the most widely used tools in molecular biology

    PCR / Nucleic acid amplification PCR: One of the most widely used tools in molecular biology What is polymerase chain reaction (PCR)? What is a PCR array? The process of replicating a specific DNA fragment though a series of thermal cycling to generate thousands to millions of copies. A PCR array or

  40. Slide 40: Digital PCR: A new level of precision and sensitivity

    PCR / Nucleic acid amplification Digital PCR: A new level of precision and sensitivity What is digital PCR? Digital PCR is a highly accurate approach for nucleic acid detection and quantification. The basic principle is the same as other PCR technologies Replicating a specific DNA fragment though a

  41. Slide 41: Digital PCR: The latest generation of PCR technology

    PCR / Nucleic acid amplification Digital PCR: The latest generation of PCR technology 1st generation 2nd generation 3rd generation Conventional PCR Quantitative RT-PCR (qPCR) Digital PCR (dPCR) Qualitative Relative quantification Absolute quantification • Technically simple • High accuracy, sensitiv

  42. Slide 42: QIAcuity: Disruptive nanoplate-based digital PCR system

    PCR / Nucleic acid amplification QIAcuity: Disruptive nanoplate-based digital PCR system Workflow advantages with QIAGEN digital PCR using novel microplate technology Fully integrated platforms Differentiated nanoplate system Partitioning, thermal cycling and imaging Launched • Each square well cont

  43. Slide 43: QIAcuity: Capturing opportunities in both dPCR and qPCR markets

    PCR / Nucleic acid amplification QIAcuity: Capturing opportunities in both dPCR and qPCR markets Longer-term ambition to convert various PCR markets QIAcuity Market Opportunity • 2021 sales: >$45 m vs. ~$10 million in 2020 ~$300 million annual digital PCR market • Launched COVID-19 research assay in

  44. Slide 44: PCR enzymes, reagents, and arrays for research workflows

    PCR / Nucleic acid amplification PCR enzymes, reagents, and arrays for research workflows QuantiNova: Automatable, ultrafast kits with in-process PCR arrays: pathway-focused panels of laboratory- controlled safety measures verified qPCR assays • PCR or 1-step & 2-step RT-PCR • Expert-designed panels

  45. Slide 45: Customized arrays: GeneGlobe design and analysis portal for biological content

    PCR / Nucleic acid amplification Customized arrays: GeneGlobe design and analysis portal for biological content A world of genes, pathways and biological targets Find NGS, PCR and functional analysis assays in the relevant scientific context. Design custom products with full flexibility on target re

  46. Slide 46: Genomics / NGS

    Universal NGS consumables Illumina collaboration NGS assays Genomics / NGS Customers Bioinformatics solutions Life Sciences Molecular Diagnostics Sample to Insight Investor handout - Q3 2021 46

  47. Slide 47: Universal NGS: QIAseq solutions providing high-performance chemistry

    Genomics / NGS Universal NGS: QIAseq solutions providing high-performance chemistry Target enrichment and streamlined library preparation leveraging leading sample preparation and bioinformatics QIAGEN NGS differentiation NGS research market Superior technology performance for target enrichment >$80

  48. Slide 48: Partnership to accelerate use of NGS in clinical decision-making

    Diagnostic solutions Partnership to accelerate use of NGS in clinical decision-making • QIAGEN to develop and market NGS IVD kits (including CDx assays) for use on Illumina systems ◦ Integrated with QIAGEN sample technologies, NGS IVD kits and bioinformatics solutions for “Sample to Insight” experie

  49. Slide 49: QIAGEN Digital Insights: Turning sequencing data into clinically actionable information

    Genomics / NGS QIAGEN Digital Insights: Turning sequencing data into clinically actionable information Bioinformatics [baɪ.oʊˌɪnfərˈmætɪks] is an interdisciplinary field that develops methods and software tools for understanding biological data. As an interdisciplinary field of science, bioinformati

  50. Slide 50: The partner of choice for actionable insights from molecular and real-world data

    Genomics / NGS The partner of choice for actionable insights from molecular and real-world data Recent multi-year partnerships Preferred vendor for Genomics Deliver custom NGS patient data Molecular oncology and England to analyze 5 million interpretation for genetic markers oncogenetic screening da

  51. Slide 51: Sustainability at QIAGEN

    Sustainability at QIAGEN Sample to Insight

  52. Slide 52: We were awarded Prime Status by ISS-ESG

    We were awarded Prime Status the sustainability ratings agency, ISS-ESG Awarded to companies with an Environmental, Social and Governance (ESG) performance above the sector-specific prime threshold, which means they fulfill ambitious absolute performance requirements We communicate our activities ar

  53. Slide 53: Dedicated to sustainability and diversity in our operations and teams

    Dedicated to sustainability and diversity in our operations and teams Environmental Social Governance 1.5-degree Celsius climate target Community Service Committee Recognizing importance of clear organizing volunteers and funds rules on corporate governance Progress in 2020: • Compliance with rules

  54. Slide 54: Environmental protection is an issue of continued and committed concern for QIAGEN

    Environmental protection is an issue of continued and committed concern for QIAGEN Eco-friendly transportation • Conversion of air freight to sea freight saving ~1.164 tons/year of CO₂ since 2018 • Reduction of Scope 1 & 2 CO₂ emissions by 9.1% in 2020 • Reduction of business travel CO₂ emissions by

  55. Slide 55: Integrating sustainability throughout the value chain

    Integrating sustainability throughout the value chain Examples of sustainability in product design • Avoiding materials that cause a lot of damage when they are mined, cannot be recycled or do not decompose • Improving repairability, longevity, and allowing for reuse • Designing products to use less

  56. Slide 56: Plastic footprint reduction

    Plastic footprint reduction Committed to reduce, replace, and recycle plastic waste without compromising the required safety and hygiene standards Reduce Reduced the thickness of blister film in packaging equating to a 2800 kg annual reduction Reduced the number of gel packs used equating a 33.4 ton

  57. Slide 57: Conducting business in a responsible way through ethical foundations

    Conducting business in a responsible way through ethical foundations Respecting human rights and legally compliant business behavior Supply Chain As part of our supplier selection process, we assess the suppliers’ policy regarding human rights issues. In addition, first-tier suppliers must confirm R

  58. Slide 58: Deepening commitment to diversity and inclusion

    Deepening commitment to diversity and inclusion Diverse teams strengthen our organization through the variety of ideas, perspectives and approaches Executive Council on Equal Opportunity (ECEO) • Created to drive change within QIAGEN around diversity and inclusion Diversity and Inclusion Ambassador

  59. Slide 59: Fostering a culture of empowerment driven by a focus on achieving targets

    Fostering a culture of empowerment driven by a focus on achieving targets Team developed and empowered to execute on our goals Decentralized decision-making Ambitious but realistic targets A culture of “doers” • Giving teams at all levels greater influence • Appropriately balance opportunity and ris

  60. Slide 60: Our employee volunteer committees drive initiatives across the organization

    Our employee volunteer committees drive initiatives across the organization Our diversity ambassadors The Mexico “QIAGreen” team regularly organize roundtables and organizes recycling events and workshops to discuss topics environmental education campaigns around inclusion and equality Our teams are

  61. Slide 61: QIAGEN operates under a two-tier corporate structure

    QIAGEN operates under a two-tier corporate structure • QIAGEN has established an Executive Committee (EC) – which comprises the CEO, the CFO and certain experienced leaders. • Under leadership of the CEO, the members of the Executive Committee share powers and responsibilities for operational manage

  62. Slide 62: Executive Committee / Managing Board

    Executive Committee / Managing Board Thierry Bernard Roland Sackers Chief Executive Officer Chief Financial Officer Joined QIAGEN in February 2015 to lead QIAGEN’s growing Joined QIAGEN in 1999 as Vice President Finance and has presence in Molecular Diagnostics, the application of Sample been Chief

  63. Slide 63: Executive Committee

    Executive Committee Dr. Thomas Schweins Jean-Pascal Viola Dr. Jonathan Sheldon Sr. Vice President, Head of Life Science Sr. Vice President, Head of Molecular Dx Sr. Vice President, Digital Insights Business Business Area Bus. Area Area Joined QIAGEN in 2004 as Vice President Corporate Joined QIAGEN

  64. Slide 64: Executive Committee

    Executive Committee Stephany Foster Barthold Piening Sr. Vice President, Head of HR Sr. Vice President, Head of Global Operations Joined QIAGEN in 2005 as Head of Global Internal Audit and Joined QIAGEN in December 2018 as Senior Vice President, was most recently Vice President, Head of Human Head o

  65. Slide 65: Supervisory Board

    Supervisory Board Lawrence A. Rosen Dr. Metin Colpan Chair of the Supervisory Board Supervisory Director Joined the Supervisory Board in 2013 and was appointed He is a co-founder of QIAGEN, its first Chief Executive Chair in 2020. He is Chair of the Audit Committee and Chair Officer and a Managing D

  66. Slide 66: Supervisory Board

    Supervisory Board Thomas Ebeling Dr. Toralf Haag Prof. Dr. Ross L. Levine Supervisory Director Supervisory Director Supervisory Director Joined the Supervisory Board in February 2021. Mr. Ebeling Dr. Toralf Haag, 54, joined the Supervisory Board and the Joined the Supervisory Board and its Science a

  67. Slide 67: Supervisory Board

    Supervisory Board Prof. Dr. Elaine Mardis Elisabeth E. Tallett Supervisory Director Supervisory Director Joined the Supervisory Board in 2014. She is a member of Joined the Supervisory Board, as well as the Audit the Science and Technology Committee and the Committee and Compensation Committee, in 2

  68. Slide 68: Scientific Advisory Board

    Scientific Advisory Board Chair Members Dr. Peter Kaspar Dr. Neville Sanjana Prof. Dr. Ross Core Faculty Member at the New Levine Leadership positions at Roche Diagnostics and bioMérieux during York Genome Center and career in diagnostics, Life Sciences and Assistant Professor at New York pharmaceut

  69. Slide 69: Financial information

    Financial information Sample to Insight

  70. Slide 70: Disciplined capital allocation strategy to support business growth while increasing returns

    Disciplined capital allocation strategy to support business growth while increasing returns Business reinvestments Fuel sustainable and profitable growth, especially in the five pillars Capital allocation strategy Value-enhancing M&A Ongoing disciplined review of bolt-on deals Share repurchase progr

  71. Slide 71: Maintaining financial flexibility with appropriate leverage and cost-efficient debt structures

    Maintaining financial flexibility with appropriate leverage and cost-efficient debt structures Debt maturity overview Leverage ratio (As of November 30, 2020) (Net debt / EBITDA) In $ millions 2 2020 1.8 2021 1.6 1.6 177 40 1.5 1.4 2022 300 175 1.3 1.2 2023 1.1 400 1 0.9 2024 27 500 111 2027 17 U.S.

  72. Slide 72: 2020: Debt composition and maturity profile

    2020: Debt composition and maturity profile Structure as of December 31, 2020 Maturities of debt instruments (In $ millions) $2.1 billion $715 billion 700 644 600 27 Cash and 518 short-term 117 Convertible investments 500 481 18 Bonds 2021 400 $1.370 billion 400 2023 300 2024 300 2027 39 500 500 200

  73. Slide 73: Q2 2021 results

    Q2 2021 results Sample to Insight

  74. Slide 74: Summary

    Summary 1 Q2 2021 results exceeded outlook • $567.3 m net sales (+28% actual, +24% CER vs. ~20% CER outlook) • $0.67 adj. diluted EPS ($0.66 CER vs. ~$0.62-0.64 CER outlook) 2 Very strong Q2 2021 non-COVID product group sales • +52% CER growth to $408 m, 72% of total sales, vs. $259 m in Q2 2020 • G

  75. Slide 75: Q2 2021: Key figures at a glance

    Q2 2021: Key figures at a glance Net sales Adjusted EPS(1) Adj. gross margin – Q2 2021 (In $ millions, at actual rates) (In $ per share, at actual rates) 68.7% 69.9% Q2 2020 +39% / +49% / +35% CER +47% CER 1,135 +22% / Adj. operating income margin – Q2 2021 $1.33 +28% / +20% CER +24% CER 815 $0.89 3

  76. Slide 76: Q2 and H1 2021: Sales by product groups

    Q2 and H1 2021: Sales by product groups (In $ million at actual rates / change in actual, CER rates) Q2 2021 Q2 2020 Actual CER H1 2021 H1 2020 Actual CER Sample technologies 203 200 1% -3% 430 354 21% 16% Diagnostic solutions(1) 154 87 76% 71% 304 183 66% 61% Of which QuantiFERON 72 33 114% 109% 12

  77. Slide 77: Q2 and H1 2021: Sales by non-COVID and COVID-19 product groups

    Q2 and H1 2021: Sales by non-COVID and COVID-19 product groups (In $ million at actual rates / change Q2 2021 Q2 2020 Actual CER % of sales H1 2021 H1 2020 Actual CER % of sales and % of 2021 sales in actual, CER rates) Non-COVID product groups 408 259 57% 52% 72% 772 562 37% 33% 68% COVID-19 produc

  78. Slide 78: Q2 and H1 2021: Sales by geographic regions

    Q2 and H1 2021: Sales by geographic regions (In $ million at actual rates / change Q2 2021 Q2 2020 Actual CER % of sales H1 2021 H1 2020 Actual CER % of sales and % of 2021 sales in actual, CER rates) Americas 257 177 45% 44% 45% 501 351 43% 42% 44% Europe / Middle East / Africa 202 164 23% 15% 36%

  79. Slide 79: Five pillars update: Investing to drive solid post-pandemic business expansion

    Five pillars update: Investing to drive solid post-pandemic business expansion 2021 CER Updated 2021 CER expectations expectations Post-COVID dynamics Q2 2021 update (December 2020) (July 2021) Sample • Sustainable low- to • Workflow Configurator launched to simplify >$750 m >$750 m technologies mid

  80. Slide 80: 2021 sales outlook: Updated perspectives

    2021 sales outlook: Updated perspectives (As of July 12, 2021) (In $ at CER) At least 12% CER ~$2.2 bn ~$2.1 bn ~ -$110 m ~ -$200 m ~ +$90 m ~ -$70 m Antigen testing ~ +$30 m Sample tech (DNA) ~ -$60 m QIAstat-Dx ~ +$25 m QuantiFERON ~ -$40 m NeuMoDx ~ +$35 m Rest of portfolio ~ -$30 m Sample tech (

  81. Slide 81: Q3 and FY 2021: Outlook and assumptions

    Q3 and FY 2021: Outlook and assumptions (As of July 12, 2021) Q3 2021 outlook FY 2021 outlook ~0% CER ≥ +12% CER Net sales (Prior year: $483.8 m) (Prior year: $1,870.3 m) Anticipated currency impact(1) ~ +1-2 p.p. ~ +2-3 p.p. ~$0.52-0.53 CER ≥ $2.42 CER Adjusted EPS(2) (Prior year: $0.58) (Prior yea

  82. Slide 82: Summary FY 2021 outlook: ≥ 12% CER sales growth, ≥ $2.42 CER adj. EPS

    Summary 1 Exceeded Q2 2021 outlook: 24% CER sales growth and $0.66 CER adj. EPS 1 2 Very strong non-COVID product group sales: +52% CER in Q2 2021, represented 72% of sales 2 3 Faster-than-expected vaccination success leading to reduced COVID-19 testing demand 4 FY 2021 outlook: ≥ 12% CER sales grow

  83. Slide 83: Appendix

    Appendix Sample to Insight

  84. Slide 84: QIAGEN sales reporting in new product groups

    QIAGEN sales reporting in new product groups Five pillars of growth Sample QIAcuity QIAstat-Dx NeuMoDx QuantiFERON QIAGEN product groups technologies(1) digital PCR(3) Consumables and instruments used in sample collection, stabilization, storage, Sample technologies(1) purification and quality contr

  85. Slide 85: 2021: Quarterly sales by product group

    2021: Quarterly sales by product group Q1 2021 Q2 2021 Q3 2021 Q4 2021 H1 2021 (In $ millions at actual rates / change in actual, CER rates) Sales Act. CER Sales Act. CER Sales Act. CER Sales Act. CER Sales Act. CER Sample technologies 227 47% 42% 203 1% -3% 430 21% 16% Diagnostic solutions(1) 150 5

  86. Slide 86: 2020: Quarterly sales by product group

    2020: Quarterly sales by product group Q1 2020 Q2 2020 Q3 2020 Q4 2020 FY 2020 (In $ millions at actual rates / change in actual, CER rates) Sales Act. CER Sales Act. CER Sales Act. CER Sales Act. CER Sales Act. CER Sample technologies 154 22% 24% 200 46% 49% 214 57% 56% 236 59% 55% 804 47% 47% Diag

  87. Slide 87: 2021: Sales by non-COVID and COVID-19 product groups

    2021: Sales by non-COVID and COVID-19 product groups Q1 2021 Q2 2021 Q3 2021 Q4 2021 H1 2021 (In $ millions at actual rates / change in actual, CER rates) Sales Act. CER Sales Act. CER Sales Act. CER Sales Act. CER Sales Act. CER Non-COVID products 364 20% 16% 408 57% 52% 772 37% 33% COVID-19 relate

  88. Slide 88: 2020: Sales by non-COVID and COVID-19 product groups

    2020: Sales by non-COVID and COVID-19 product groups Q1 2020 Q2 2020 Q3 2020 Q4 2020 FY 2020 (In $ millions at actual rates / change in actual, CER rates) Sales Act. CER Sales Act. CER Sales Act. CER Sales Act. CER Sales Act. CER Non-COVID products 303 -5% -4% 259 -25% -23% 320 -8% -8% 371 0% -2% 1,

  89. Slide 89: 2021: Quarterly sales by product type, customer class and region

    2021: Quarterly sales by product type, customer class and region (In $ millions at actual rates / change in actual, CER rates) Q1 2021 Q2 2021 Q3 2021 Q4 2021 H1 2021 Product type Sales Act. CER Sales Act. CER Sales Act. CER Sales Act. CER Sales Act. CER Consumables and related revenues 498 53% 48%

  90. Slide 90: 2020: Quarterly sales by product type, customer class and region

    2020: Quarterly sales by product type, customer class and region (In $ millions at actual rates / change in actual, CER rates) Q1 2020 Q2 2020 Q3 2020 Q4 2020 FY 2020 Product type Sales Act. CER Sales Act. CER Sales Act. CER Sales Act. CER Sales Act. CER Consumables and related revenues 326 4% 6% 37

  91. Slide 91: Q2: Consolidated Statements of Income (unaudited)

    Q2: Consolidated Statements of Income (unaudited) Three months ended Three months ended (In $ thousands, except share data) June 30, 2021 June 30, 2020 Net sales 567,308 443,252 Cost of sales: Cost of sales 180,388 133,340 Acquisition-related intangible amortization 17,732 14,942 Total cost of sales

  92. Slide 92: H1: Consolidated Statements of Income (unaudited)

    H1: Consolidated Statements of Income (unaudited) Six months ended Six months ended (In $ thousands, except share data) June 30, 2021 June 30, 2020 Net sales 1,134,514 815,349 Cost of sales: Cost of sales 359,362 246,787 Acquisition-related intangible amortization 35,373 30,054 Total cost of sales 3

  93. Slide 93: 2021: Quarterly income statement summary

    2021: Quarterly income statement summary (In $ millions, unless indicated) (Diluted EPS in $ per share) Q1 2021 Q2 2021 Q3 2021 Q4 2021 H1 2021 Net sales 567.2 567.3 1,134.5 Net sales (CER) 549.5 547.7 1,097.2 Gross profit 370.6 369.2 739.8 Gross profit margin 65.3% 65.1% 65.2% Adjusted gross profit

  94. Slide 94: 2020: Quarterly and full-year income statement summary

    2020: Quarterly and full-year income statement summary (In $ millions, unless indicated) (Diluted EPS in $ per share) Q1 2020 Q2 2020 Q3 2020 Q4 2020 FY 2020 Net sales 372.1 443.3 483.8 571.2 1,870.3 Gross profit 243.5 295.0 320.8 373.4 1,232.7 Gross profit margin 65.5% 66.5% 66.3% 65.4% 65.9% Adjus

  95. Slide 95: Q2 and H1 2021: Reconciliation adjusted results (unaudited)

    Q2 and H1 2021: Reconciliation adjusted results (unaudited) (In $ millions, except EPS) Net Gross Operating Pretax Income Tax Net Diluted Second quarter 2021 sales profit income income tax rate income EPS Reported results 567.3 369.2 161.3 149.9 (28.8) 19% 121.1 0.52 Adjustments Business integration

  96. Slide 96: Q2 and H1 2021: Footnotes for reconciliation adjusted results (unaudited)

    Q2 and H1 2021: Footnotes for reconciliation adjusted results (unaudited) (a) Results for 2021 include continued integration-related activities for the NeuMoDx acquisition completed in September 2020. Results for 2020 include expenses associated with the public takeover offer for QIAGEN. A restructu

  97. Slide 97: Q2 and H1 2021: Currency impact

    Q2 and H1 2021: Currency impact Net sales Net sales Currency exposure Change (In $ millions/Actual) (CER) (As % of CER sales) (In $ millions) Second quarter 2021 U.S. dollar 292.2 292.2 53% 0.0 Euro 125.6 114.9 21% -10.7 British pound 22.4 19.9 4% -2.5 Japanese yen 13.8 14.0 3% 0.3 Other currencies

  98. Slide 98: Consolidated Balance Sheets

    Consolidated Balance Sheets June 30, December 31, June 30, December 31, (In $ thousands, except par value) 2021 2020 (In $ thousands, except par value) 2021 2020 Assets (unaudited) Liabilities and Equity (unaudited) Cash and cash equivalents 759,047 597,984 Current portion of long-term debt − 42,539

  99. Slide 99: Consolidated Statements of Cash Flows (unaudited)

    Consolidated Statements of Cash Flows (unaudited) Six months ended Six months ended June 30, June 30, June 30, June 30, (In $ thousands) 2021 2020 (In $ thousands) 2021 2020 Cash flows from operating activities: Cash flows from financing activities: Net income 250,274 129,593 Repayment of long-term

  100. Slide 100: Employees as of June 30, 2021

    Employees as of June 30, 2021 Europe / Asia Pacific / Total Total Americas Middle East / Africa Japan / ROW Q2 2021 Q2 2020 Change Production 435 1,217 153 1,805 1,270 42% R&D 219 670 50 939 880 7% Sales 574 865 801 2,240 2,127 5% Marketing 77 184 84 345 320 8% Administration 82 388 162 632 594 6% T

  101. Slide 101: Your contacts

    Your contacts John Gilardi Vice President Corporate Communications and IR Calendar Phone: +49 2103 29 11711 Q3 2021 results November 2021 +1 240 686 2222 Mobile: +49 152 018 11711 Q4 2021 results February 2022 E-mail: john.gilardi@qiagen.com Phoebe Loh Senior Director Share information Global Invest

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