Micropos Medical Ab · NGM:MPOS

Micropos Medical Ab — Technical Presentation (December 2023)

17 slides from Micropos Medical Ab's technical presentation, December 2023

  1. Slide 1: Raypilot vs Gold Markers

    Raypilot vs Gold Markers Johannes Berchtold Universitätsklinik für Radiotherapie und Radio-Onkologie, Salzburger Landeskliniken, Müllner Hauptstraße 48, 5020 Salzburg, Austria. RayPilot Usermeeting - 2023

  2. Slide 2: Methods

    Methods  12 Patients (metastatic á 6x6 Gy  64 Fractions  kV-Images  Gold Markers  HypoCath with fixation RayPilot Usermeeting 2023 – Johannes Berchtold 2

  3. Slide 3: Prerequisites

    Prerequisites Demanding the HypoCath to act as a substitution for gold-marker IGRT requires:  HypoCath system measures the same offset as the kV-IGRT system  Inter - and Intrafractional stability within the urethra  Only axial stability was monitored RayPilot Usermeeting 2023 – Johannes Berchtold

  4. Slide 4: Where to get the data - Database

    Where to get the data - Database  Data is stored in SQL Database  Python skript to vizualize and analyse motion  Allows creating hypothetical fractions (without HypoCath) RayPilot Usermeeting 2023 – Johannes Berchtold 4

  5. Slide 5: Hypothetical Fractions

    Hypothetical Fractions Original  Without any interruptions  Overall treatment time is shorter Hypothetical  Since movement correlates with time – less movement RayPilot Usermeeting 2023 – Johannes Berchtold 5

  6. Slide 6: Where to get the data - Images

    Where to get the data - Images  kV-images at 180°were superimposed for inter-and intrafractional stability  image pairs at 180°and 130° were used to evaluate accuracy of motion-detection  Images are referenced to HypoCath-interactions using a timestamp RayPilot Usermeeting 2023 – Johannes Berchto

  7. Slide 7: Initial kV-image pair

    Initial kV-image pair  Used for interfractional catheter stability (all first images)  Images taken at 180° were evaluated RayPilot Usermeeting 2023 – Johannes Berchtold 7

  8. Slide 8: Intermediate kV-image pair(s)

    Intermediate kV-image pair(s)  Used for repositioning  Allows evaluation prostate motion parameters recorded by the HypoCath system compared to IGRT- based values  Compared with first image to evaluate catheter stability RayPilot Usermeeting 2023 – Johannes Berchtold 8

  9. Slide 9: Final kV-image pair

    Final kV-image pair  Aquired after treatment  Compared with first image pair to determine intrafractional catheter stability RayPilot Usermeeting 2023 – Johannes Berchtold 9

  10. Slide 10: Difference Transmitter – GM-IGRT

    Difference Transmitter – GM-IGRT 45 40 Number Of Fractions 35 30 25 20 15 10 5 0 -0,6 -0,5 -0,4 -0,3 -0,2 -0,1 0 0,1 0,2 0,3 0,4 0,5 0,6 Difference Transmitter - Image Registration in cm Longitudinal Lateral Vertikal RayPilot Usermeeting 2023 – Johannes Berchtold 10

  11. Slide 11: Difference Transmitter – GM-IGRT: Phantom measurements

    Difference Transmitter – GM-IGRT: Phantom measurements RayPilot Usermeeting 2023 – Johannes Berchtold 11

  12. Slide 12: Intrafractional Stability

    Intrafractional Stability 80 70 67 Number Of Fractions 61 60 50 Not really 40 Bladder cramps rational? 30 reported 20 by the patient 10 10 7 7 3 1 1 2 2 2 1 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -0,6 -0,5 -0,4 -0,3 -0,2 -0,1 0 0,1 0,2 0,3 0,4 0,5 0,6 0,7 0,8 0,9 Difference Transmitter - interfra

  13. Slide 13: Interfractional Stability

    Interfractional Stability 35 33 31 30 Number Of Fractions 25 20 15 11 10 6 5 4 4 5 2 2 2 1 1 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 -0,6 -0,5 -0,4 -0,3 -0,2 -0,1 0 0,1 0,2 0,3 0,4 0,5 0,6 Difference Transmitter - interfractional in cm < Right | Left > < Cranial | Caudal > Cranial / Caudal Right / Left RayPil

  14. Slide 14: Accuracy… is about timing it right

    Accuracy… … is about timing it right RayPilot Usermeeting 2023 – Johannes Berchtold 14

  15. Slide 15: Accuracy… is all about time

    Accuracy…  Imaging takes a lot of time – CBCT vs kV  Compensating prostate movement directly by controlling the treatment couch via RayPilot saves time  FFF decreases beam-on time … is all about time RayPilot Usermeeting 2023 – Johannes Berchtold 15

  16. Slide 16: Coming back to Accuracy

    Coming back to Accuracy  The same actions to keep the data as valid as possible also guarantee more precise treatment – without and without HypoCath  letting patients rest one or two minutes after taking place on the treatment couch  forcing patients to drink too huge amounts of water increases t

  17. Slide 17: Thank You

    Thank You RayPilot Usermeeting 2023 – Johannes Berchtold 17

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