Royalty Pharma Plc · NASDAQ:RPRX

Royalty Pharma — Merger or Acquisition (June 2025)

8 slides from Royalty Pharma's merger presentation, June 2025

  1. Slide 1: Royalty Pharma

    ROYALTY PHARMA

  2. Slide 2: Daraxonrasib royalty acquisition

    Daraxonrasib royalty acquisition June 2025

  3. Slide 3: Forward Looking Statements

    Forward Looking Statements This presentation has been prepared by Royalty Pharma plc (the “Company”), is made for informational purposes only and does not constitute an offer to sell or a solicitation of an offer to buy securities. The information set forth herein does not purport to be complete or

  4. Slide 4: Daraxonrasib a potential practice-changing medicine for cancer

    Daraxonrasib a potential practice-changing medicine for cancer 1 2 3 Daraxonrasib is in Phase 3 Impressive clinical results Multi-blockbuster for pancreatic & lung cancer and favorable safety commercial opportunity Revolution Medicines’ daraxonrasib, a RAS(ON) Large Phase 1 study demonstrated effica

  5. Slide 5: RP provides up to $2 billion of flexible and scaled funding

    RP provides up to $2 billion of flexible and scaled funding Daraxonrasib consensus sales projections (Unadjusted sales; $ in millions) • Up to $1.25bn ($250m upfront) for synthetic royalty on daraxonrasib(1) ▪ Tranched structure limits risk as additional funding available on positive $7,311 $6,806 P

  6. Slide 6: Initial clinical results demonstrate impressive efficacy

    Initial clinical results demonstrate impressive efficacy Large Phase 1 trial enrolled over 400 patients Daraxonrasib clinical results to date 2L pancreatic cancer cohort(1,3) 2L lung cancer cohort(2,3) (PDAC) (NSCLC) 17.7 14.5 11.3-11.8(5) 9.8 8.5 6.1-6.9(4) 3.7-4.5(5) 2.0-3.5(4) Progression free su

  7. Slide 7: Royalty Pharma sees multi-blockbuster potential for daraxonrasib

    Royalty Pharma sees multi-blockbuster potential for daraxonrasib Revolution Medicines would likely launch with a significant first to market advantage in a space where the unmet need is profound Pancreatic cancer(1,2) Non-small cell lung cancer(2) Strengthens Zoldonrasib(3), other RAS- ~56,000 new U

  8. Slide 8: Daraxonrasib royalty and debt facility terms

    Daraxonrasib royalty and debt facility terms Royalty terms Tranche 1 Tranche 2 Tranche 3(1) Tranche 4(1) Tranche 5(1) Total Amount $250m $250m Up to $250m Up to $250m Up to $250m $1.25bn Positive data FDA approval in 2L Sales milestone Positive Phase 3 data in Timing Immediate (RASolute 302) pancrea

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