Slide 1: Advanced Technology to Reduce Pain & Inflammation
Advanced Technology to Reduce Pain & Inflammation.
Slide 2: 5x Better Compared to OTC Drugs & 100% Safer
5x Better Compared to OTC Drugs & 100% Safer 90 8-hourTreatments for $0.25 each
Slide 3: Contents
Contents Product Benefits Product Portfolio History Pulsed Shortwave Therapy History Of Pain Relief Dr. OZ Show – Market Size Intellectual Property Clinical Evidence Marketing Support & Distribution Management & Medical Advisory Board BioElectronics Corporation | www.bielcorp.com
Slide 4: ActiPatch - Long Lasting, Full Body Pain Relief
ActiPatch- Long Lasting, Full Body Pain Relief Technologically advanced & clinically proven Compared to Tylenol 5 x More Effective 100% Safer ½ the Cost
Slide 5: ActiPatch Comparison to Therapies for Undefined Lower Back Pain
ActiPatch - Comparison to Therapies for Undefined Lower Back Pain* 4 MEAN PAIN DECREASE (VAS POINTS) 3.5 3 2.5 2 3.53 ActiPatch Mean Pain 1.5 Decrease compared to 1 2 1.8 1.7 published clinical data 0.5 1.15 1.05 0.8 shows greater pain 0.7 0.7 0 relief is achieved with ActiPatch *Analgesic effects o
Slide 6: ActiPatch Compared to NSAIDs and Paracetamol on Lower Back Pain
ActiPatch Compared to NSAID’s and Paracetamol on the Efficacy of Reducing Lower Back Pain 4 3.5 ActiPatch achieves a PAIN DECREASE (VAS POINTS) 3 5 fold greater pain 2.5 reduction than 2 3.5 commonly used over 1.5 the counter pain 1 medications 0.5 0.7 0 ActiPatch NSAID's/paracetamol BioElectronics
Slide 7: What Makes Our Products So Great Compared to Drug Therapy?
What Makes Our Products So Great Compared to Drug Therapy? 5 fold superior pain relief and 100% safer Innovative award-winning technology that solves the source of pain instead of masking the pain – Wall Street Journal Medical Innovation Award Comprehensive clinical support Unique Bio-Dynami
Slide 8: Pulsed Shortwave Therapy
PULSED SHORTWAVE THERAPY Historical Use of Pulsed Shortwave Therapy Physicians, sports trainers, and therapist around the world have used pulsed shortwave therapy in clinics successfully for more than eighty years to reduce pain, inflammation and accelerate healing. Pain and inflammation are the f
Slide 9: Established Proven Pain Therapy
Established Proven Pain Therapy Clinician administered Patient administered Large bulky equipment Small, light, inexpensive and Required multiple office visits portable No office visits Superior pain therapy with extended relief BioElectronics Corporation | www.bielcorp.com
Slide 10: Historic Uses
HISTORIC USES Post-Surgical Orthopedic Conditions Post Operative Knee Repair Ankle Sprains Repair of Ankle Fracture Lower Back Pain Abdominoplasty Tennis Elbow Rhytidectomy Carpal Tunnel Breast Augmentation Frozen Shoulder Liposculpture Tendonitis Blepharoplasty Heel Pain Rhinoplasty 1010 Chronic Wo
Slide 11: Technology Overview
Technology Overview Pulsed Shortwave Therapy – dual mechanism of action Thermal Non-Thermal Highly Effective Mechanism Mechanism Therapy BioElectronics Corporation | www.bielcorp.com
Slide 12: Influence of Pulse Rate and Duty Cycle in Shortwave Diathermy
Influence of Pulse Rate and Duty Cycle in Shortwave Diathermy Thermal Mechanism Traditional BioDynamic Rapid pulse rate – accumulation of thermal & non-thermal effects ActiPatch utilizes a 1 KHz pulse rate with 50% duty cycle BioElectronics Corporation | www.bielcorp.com
Slide 13: How ActiPatch Works
How ActiPatch Works Inflamed injured tissue is the primary source of pain The inflammation response is the body’s response to injury to prevent infection. • The visible signs are redness, heat, swelling and pain in the tissue. • During the inflammatory process cell to cell contact is interrupted to
Slide 14: History of Modern Pain Relief
History of “Modern” Pain Relief Menthol for Ibuprofen from the TENS Units- US external pain relief Boots Group /Advil Patents in Germany 1771 1960’s 1970’s 2012 1899 1970’s 1990’s Bayer invents & Naproxen (Cox Air Activated Heat - distributes Aspirin Inhibitor)/ Aleve, Japan for Dr’s Anaprox BioElec
Slide 15: 5 Fold Superior Pain Relief & 100% Safer
5 Fold Superior Pain Relief & 100% Safer BioElectronics Corporation | www.bielcorp.com
Slide 16: ActiPatch Device
ActiPatch Device 90 Clinically Proven Treatments 8-Hours Each Innovative Sensation & Odor Free Technology 24/7 Continuous Pain Relief. BioElectronics Corporation | www.bielcorp.com
Slide 17: Product Portfolio
Product Portfolio Clinically Tested – Patented Technology – Doctor Recommended • Back Pain • Body Pain Patches • Knee Pain • Wrist & Elbow Pain • Heel Pain BioElectronics Corporation | www.bielcorp.com
Slide 18: The Dr. Oz Show
The Dr. Oz Show: “The natural Pulsed electromagnetic field solution (PEMF) therapy is the revolutionary to pain” cure for pain Today we are changing the practice “Brand new of medicine with PEMF, you don’t idea and we just feel better you are better need to embrace it” The new natural solution
Slide 19: Dr. Oz Explains the Therapy
Dr. Oz Explains the Therapy BioElectronics Corporation | www.bielcorp.com
Slide 20: Musculoskeletal Pain
Musculoskeletal Pain ActiPatch Shows Significant Reduction in Musculoskeletal Pain 50% 39.67% 40% 30% 20% 10% 7.28% 0% Active Placebo US 60+ Million US 30+ Million ActiPatch Achieves Superior Pain People People Reduction Compared to Extra Strength Tylenol 60% 52.80% 50% 40% 30% 21.10% 20% 10% 0% Act
Slide 21: Problems with Existing Traditional Pain Management Products
Problems with Existing Traditional Pain Management Products Analgesics - Aspirin, Acetaminophen, Voltarol®, Ibuprofen, Naproxen -Short duration -Side effects: Upset stomach, drug interaction risks, allergies -Difficulty swallowing pills -Minimally effective Topical Analgesics - Icy Hot®, Voltarol®,
Slide 22: Intellectual Property
Intellectual Property Patents – Issued Applications 5 Patents – Allowed Applications 2 Patents - Pending/Published Applications 9 International Trademarks 6 BioElectronics Corporation | www.bielcorp.com
Slide 23: Regulatory Clearances
REGULATORY CLEARANCES European Union (CE) – For the Application of Edema Reduction, Swelling, Pain, and Inflammation (Class IIa, OTC) Health Canada – Relief of pain associated with musculoskeletal complaints and relief of menstrual pain (Class II, OTC) Australia (TGA) – For the Application of
Slide 24: Recent Published Articles
Recent Published Articles Publication date Study Journal Author Institution estimate Oesteoprogeniter Journal of cell differentiation published Dr Russell Reid Chicago Craniofacial Surgery in to bone DOMS marathon Pain June - July Dr Sten Rasmussen Aalborg hospital runners Review wound Submitted- Wo
Slide 25: Current Clinical Trials
Current Clinical Trials Primary Principal Study Location Outcome Enrollment Status Investigator Measure University British Pain at 4 weeks, Professor Jack Columbia, Plantar Fasciits follow up at 6 40 recruiting Taunton Vancouver, months Canada Denver Medical Pain week 1,2 Venous Ulcer Pain Eric Jako
Slide 26: Current Clinical Trials
Current Clinical Trials Primary Principal Study Location Outcome Enrollment Status Investigator Measure Analgesic University IRB protocol Hernia Surgical Dr Frederik medication use Hospital Ghent, under Recovery Berreveot and pain over 7 Ghent, Belgium development day recovery. Dr Sten AARHUS UNIVER
Slide 27: Pilot Studies
Pilot Studies Study Principal Investigator Location Outcome measure Status New York Headache Migraine Dr. Alexander Mauskop Reduction in migraine Samples sent Center, New York, NY Patients actively Diabetic peripheral Dr. Perry Mayer MayerInstitute Neuropathic pain recruiting treatment neuropathy pa
Slide 28: Pilot Studies
Pilot Studies Principal Outcome Study Location Status Investigator measure Blepharoplasty# Indonesia ? Edema day 1, 2, 3 Starting April Hip, Knee, and Dr. Thiago Fukuda Sports Group Reduction in Impinged Shoulder* Samples sent Santa Casa de São shoulder pain Paulo, Brazil Samples sent for Rhinoplast
Slide 29: Marketing Support
Marketing Support Print Television Key Opinion Pharmacist Public Relations Leaders - Dr. Detailing Driven Demand Conveying the following messages: 1. ActiPatch and Allay deliver both electrical and magnetic energy at the site of pain 2. Clinically proven technology 3. Dr. Oz recommended 4. Wall Stre
Slide 30: Retail Marketing Support
Retail Marketing Support Point of Purchase Retail Displays: Well designed in-store displays provide product education as well as a call to action to induce an immediate purchase. Displays include a QR Code and a SMS Text number to provide consumers with access to more in-depth product informatio
Slide 31: Retailers Benefits
Retailers Benefits 1.) Increased register ring and penny profit vs. existing products 2.) High turnover item. Once consumer uses it they have to continue to maintain pain relief 3.) New technology in a stodgy, old fashioned segment 4.) Both consumer and doctor driven demand 5.) New product pipeline/
Slide 32: Board of Directors
BOARD OF DIRECTORS Richard Staelin, Ph. D. - Chairman of Board of Directors Professor The Fuqua School of Business, Duke University. Past Executive Director of Marketing Science Institute and has held numerous positions at the American Marketing Association (AMA) and The Institute of Management Sc
Slide 33: Management Team
MANAGEMENT TEAM Andrew J. Whelan - President & CEO Mr. Whelan is a founder of the Company and has served as the President and Chairman of the Board of Directors since April 2000. He is a seasoned business executive with a strong financial, consulting and management background. From 1993 to April 2
Slide 34: Management Team Cont'd
MANAGEMENT TEAM CONT’D John Martinez, Senior Engineer Mr. Martinez has served as Senior Engineer of the Company since April 2002. Mr. Martinez holds a Bachelors of Applied Science degree in Electronics Engineering Technology from ITT Technical Institute where he graduated with highest honors, and
Slide 35: Medical Advisory Board
MEDICAL ADVISORY BOARD Lawrence L. Michaelis, M.D., M.S. Chairman of the BioElectronics Medical Advisory Board. Physician, entrepreneur, business physician educator, and former Associate Dean Northwestern University Medical School. Author of over 130 peer-reviewed journal articles. NIH researcher,