Jubilant Pharmova Limited · NSE:JUBLPHARMA

Jubilant Pharmova — Investor Day (February 2025)

68 slides from Jubilant Pharmova's investor day presentation, Feb 24, 2025

  1. Slide 1: Stock exchange cover letter for investor and analyst meet

    February 24, 2025 BSE Limited National Stock Exchange of India Limited Floor 25, P. J. Towers Exchange Plaza Dalal Street, Fort Bandra Kurla Complex Mumbai - 400 001 Bandra (E) Mumbai - 400 051 Scrip Code: 530019 Symbol: JUBLPHARMA Sub.: Presentation for Investor and Analyst Meet Ref: Regulation 30

  2. Slide 2: Investor & Analyst Meet Feb'25

    Investor & Analyst Meet Feb’25

  3. Slide 3: Forward-looking statements disclaimer

    Statements in this document relating to future status, events, or circumstances, including but not limited to statements about plans and objectives, the progress and results of research and development, potential product characteristics and uses, product sales potential and target dates for product

  4. Slide 4: Group leadership

    Shyam S Bhartia Hari S Bhartia Priyavrat Bhartia Arjun S Bhartia Chairman Co-Chairman Managing Director Joint Managing Director Arvind Chokhany Shantanu Jha Dr Tushar Gupta Group CFO, Whole-time Director Group CHRO Head - Corporate Strategy 3

  5. Slide 5: Business CEOs

    Harsher Singh Chris Preti Giuliano Perfetti CEO - Jubilant Radiopharma CEO - CDMO Sterile Injectables CEO - CRDMO, Biosys Dr Jaidev Rajpal Kyle Ferguson Dr Syed Kazmi CEO - Jubilant Generics CEO - Allergy Immunotherapy CEO - Jubilant Therapeutics 4

  6. Slide 6: Agenda

    Overview Arjun Bhartia Vision 2030 Priyavrat Bhartia Radiopharma Harsher Singh CDMO Sterile Injectables Chris Preti CRDMO Giuliano Perfetti Allergy Immunotherapy Kyle Ferguson Generics Dr Jaidev Rajpal Proprietary Novel Drugs Dr Syed Kazmi Summary Arvind Chokhany Q&A – starts at 7 pm Management Pane

  7. Slide 7: Overview

    Overview Arjun S Bhartia Joint Managing Director

  8. Slide 8: Strong presence in diverse sectors

    Strong presence in diverse sectors • Pharmaceuticals • Contract Research & Development Services • Life Science Ingredients • Therapeutics • Performance Polymers • Auto Dealerships • Food Service (QSR) • Oil and Gas services Global presence through investments • India • Europe • Africa • USA • Singap

  9. Slide 9: Business portfolio overview

    Radiopharma Allergy Immunotherapy CDMO Sterile Injectables Leading manufacturer 2nd largest player Leading contract manufacturer of Radiopharmaceuticals in the US Allergenic extract market in North America in North America Sole supplier of Venom Serves top global innovator pharma 2nd largest radioph

  10. Slide 10: Business wise and geography wise revenue split

    Business wise Revenue Split Geography wise Revenue Split FY24 FY24 India, 3% Generics, Rest of 12% World, Europe, 7% 9% Allergy Immunotherapy, 10% Radiopharma, 45% CRDMO, North 16% America, 80% CDMO - SI, 17% Specialty Products (Radiopharma, Allergy Immunotherapy) and Specialty Services (CDMO & CRDM

  11. Slide 11: Manufacturing and research facilities

    Kirkland, Montreal, Canada Spokane, Washington, US CDMO – SteriIe Injectables Radiopharmaceuticals CDMO – SteriIe Injectables Allergy Immunotherapy NORTH AMERICA 6 Manufacturing facilities Roorkee, Uttrakhand, India - Generics Nanjangud, Karnataka, India - CDMO API 2 Research facilities INDIA 46 Rad

  12. Slide 12: US FDA status of sites

    Business Location US FDA Status Radiopharmaceutical Montreal, Canada VAI Apr, 2024 Allergy Immunotherapy Spokane, US VAI Relentless focus on quality Sep, 2024 • Anytime audit readiness CDMO-Sterile Injectables Spokane, US VAI Sep, 2024 • Bottoms - up quality culture VAI • Continuous investments in i

  13. Slide 13: Vision 2030

    Vision 2030 Priyavrat Bhartia Managing Director

  14. Slide 14: FY23 - TTM Dec'24 Progress

    FY23 - TTM’Dec’24 Progress Revenue : Rs. 7,064 Cr. EBITDA Margin : 16.3% Net Debt/ EBITDA : 1.4x Revenue : Rs. 6,282 Cr. EBITDA Margin : 13.1% Net Debt/ EBITDA : 2.9x • Strengthened quality culture • Investment in people and leadership • Transformed Generics and Radiopharmacies FY23 TTM Dec'24 13

  15. Slide 15: 2x Revenue, 25% EBITDA Margin, Zero Net Debt

    From To FY24 FY30* 2x Revenue Rs. 6,703 Cr. Rs. 13,500 Cr. 25% EBITDA Margin ~ 15 % 23% to 25% Zero Net Debt Rs. 2,457 Cr. Zero High Teens RoCE High Single digit High Teens * Future numbers projected on constant currency basis 14

  16. Slide 16: Business Growth Drivers

    Business Growth Drivers Leadership in Ruby-Fill® Radiopharma Launch New PET, SPECT and Therapeutic products (MIBG) Invest in 6 high margin PET Radiopharmacies in US CDMO - Sterile Injectables Double capacity in Spokane, US Add large pharma customers CRDMO Grow CDMO and custom manufacturing in API Al

  17. Slide 17: Radiopharma

    Radiopharma Harsher Singh CEO - Jubilant Radiopharma

  18. Slide 18: Radiopharmaceuticals have a growing role in treatment of life-threatening diseases

    SPECT PET Radiopharmaceutical Imaging Imaging Therapeutics Low Energy High Energy Systemically or Locally gamma rays positrons Delivered detected by SPECT cameras detected by a PET scanner radiation using pharmaceuticals Isotopes - Tc99m Isotopes - Rb82, F18, Ga68 Isotopes – I131, Lu177, Ac225 MAA,

  19. Slide 19: US radiopharmaceutical market growth drivers and trends

    US Radiopharmaceutical Market Growth Drivers & Trends USD Bn. ~ 20 Launch of advanced • PSMA Therapeutic, Pluvicto for Prostrate Cancer ~USD 2.0 Bn. Therapies CAGR: New • PSMA Diagnostics for Prostrate Cancer ~ USD 1.5 Bn. 20%+ • Broad range of applicability e.g. Alzheimer’s products in • Special re

  20. Slide 20: Radiopharma product portfolio by indication

    Organ Key Indication Product PET Dx Cardiac Coronary Artery disease Ruby - Fill® Breast Lymph nodes detection Sulfur Colloid Cardiac blood pool imaging Tc99m-Gluceptate Cardiac • Diversified across diagnostics & therapeutics Coronary Artery Disease Tc99m-Sestamibi • Current TAM at USD 400 Mn. Gastro

  21. Slide 21: Radiopharma revenue and EBITDA margin trajectory

    Revenue: More than 2x of FY24 EBITDA Margin: More than 50% Growth drivers: • Ruby-Fill® Revenue: Rs. 952 Cr. • New PET & EBITDA Margin: 50% Revenue: Rs. 872 Cr. SPECT products EBITDA Margin: 53% • MIBG FY23 FY24 FY30 20

  22. Slide 22: Ruby-Fill Rubidium generator and Elusion System

    Ruby-Fill ® Rubidium 82 generator and Elusion System Growth drivers: Competitive advantage • Ruby-Fill® • Longer life per generator (7 weeks vs 6 weeks for peer) • New PET & SPECT • Better image quality and consistency products • Saline Push feature • MIBG Current Position • Market Size ~ USD 160 Mn

  23. Slide 23: Developing new products in SPECT and PET imaging

    Developing new products in SPECT Imaging to maintain leadership & in PET Imaging for growth Growth drivers: • Ruby-Fill® Incremental TAM Potential Peak Annual Timeline No. of launches • New PET & SPECT USD Mn. Sales - USD Mn. products FY27 50 20 2 • MIBG FY28 250 60 3 FY29 250 40 4 Total 550 120 9 2

  24. Slide 24: HICON Sodium Iodide I 131 and MIBG

    HICON® Sodium Iodide I 131 - Commercialised MIBG - Undergoing Clinical trials Growth drivers: • Ruby-Fill® • Potential peak sales • New PET & SPECT USD 70 - 100 Mn. products • Data package to FDA • MIBG by H2’FY26 • Iodine I 131, HICON® is standard care for patients • Used in imaging & treatment for

  25. Slide 25: Radiopharmacy

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  26. Slide 26: Radiopharmacy growth drivers and trends

    SPECT Radiopharmacy PET Radiopharmacy Growth Drivers & Trends • Large M&A transactions in Radiopharmacies • Increasing demand for novel PET products driving PET radiopharmacies growth • Stringent USP 825 regulations to drive increase in therapeutics dispensing through Pharmacy 25

  27. Slide 27: Radiopharmacy network

    nd 46 Current SPECT Current Cyclotron 6 New PET SITES Radiopharmacies USP<825> JDR network is USP 825 with ~ 20% WD compliant Portland volume market MT ND ME share OR MN VT ID Saginaw NH SD Minneapolis WI NY Business moat 1,800 Boston Detroit Wilkes WY MI Barre Phila- RI Unique combination of delphi

  28. Slide 28: Radiopharmacy revenue and EBITDA margin trajectory

    Revenue: 2x of FY24 EBITDA Margin: ~ 7% to 8% Revenue: Rs. 2,050 Cr. EBITDA Margin: 3% Revenue: Rs. 1,681 Cr. EBITDA Margin: (5%) FY23 FY24 FY30 27

  29. Slide 29: PET expansion

    Growth driver: • PET expansion • Strengthened network to enable long term contracts with PET radiopharmaceutical manufacturers • Fully operational by FY28. Funding through internal accruals and long-term credit • Expect Asset turnover of 1.0x and RoCE 20% + on the USD 50 Mn. investment 28

  30. Slide 30: CDMO - Sterile Injectables

    CDMO - Sterile Injectables Chris Preti CEO - CDMO Sterile Injectables

  31. Slide 31: CDMO-SI growth drivers and trends

    Global CDMO-SI Market Size Growth Drivers & Trends USD Bn 20 17 16 14 • Increasing number of drugs in Biologics 13 pipeline and Loss of exclusivity • Consolidation in supply due to large acquisitions - Catalent Inc. by Novo Holding 2023 2024 2025 2026 2027 Vial filling ( Units in Billions ) Year 202

  32. Slide 32: Top pharma companies as customers

    • 5 of the top 20 pharma companies as customers • 5+ years average relationship time with Top 10 Customers • 90%+ repeat customer business • 24 months of switching timelines for customers • 10+ years of US FDA compliant status at flagship site in Spokane 31

  33. Slide 33: CDMO-SI revenue and EBITDA margin trajectory

    Revenue : More than 2x of FY24 EBITDA Margin : More than 25% Revenue : Rs. 1,117 Cr. EBITDA Margin : 17% Revenue : Rs. 1,155 Cr. EBITDA Margin : 30% FY23 FY24 FY30 32

  34. Slide 34: Doubling capacity timeline

    Growth driver: • Doubling Capacity Timeline FY’24 FY’25 FY’26 FY’27 FY’28 LINE 3 Installation Media Fill Tech Transfer Commercial Production LINE 4 Design Construction Installation Media Fill Commercial Production • Total investment at USD 285 Mn. ( RoCE > 20%) including US Govt. funding of USD 150

  35. Slide 35: CRDMO: Drug Discovery Services, CDMO, API

    CRDMO: Drug Discovery Services, CDMO API Giuliano Perfetti CEO - CRDMO, Biosys

  36. Slide 36: Growth drivers and trends

    Drug Discovery Services Market Size USD Bn. Growth Drivers & Trends 10 8 Drug Discovery Market • Biosecure Act advantage • Rise in specialized technologies such as ADCs and oligonucleotides 2023 2028 CDMO API Market Size USD Bn. CDMO API Market 130 95 • Rising interest in custom generics • Rapid mom

  37. Slide 37: Top pharma companies as customers

    • 8 of the top 20 pharma companies as customers with 5x increase in revenue share from large pharma • Indian Leader for “Integrated Drug Discovery”, with a track record of +85 programs and Big pharma strategic partnership • Strengthen European penetration, with multifold revenue increase • Fully int

  38. Slide 38: Drug discovery services, early CDMO, late CDMO and APIs

    Drug Discovery Services & Early CDMO Late CDMO & APIs Integrated Chemistry Research Contract Development & Advanced Intermediate CoE Biologics Drug Discovery Centre Innovation Centre Manufacturing Centre & ( St. Julien, France ) (IDDC, Bengaluru) (CIRC, G. Noida) (API CDMC) API Manufacturing ~ 35 Sc

  39. Slide 39: CRDMO revenue and EBITDA margin trajectory

    Revenue: ~ 3x of FY24 EBITDA Margin: More than 25% Revenue: Rs. 531 Cr. EBITDA Margin: 24% Revenue: Rs. 449 Cr. EBITDA Margin: 24% Revenue : Rs. 522 Cr. EBITDA Margin : 31% FY23 FY24 TTM Dec'24 FY30 38

  40. Slide 40: Biosecure Act

    Growth driver: • Add large pharma • Executing strategy on large pharma Biosecure Act • Footprint in EU • Act passed in Sep’24 by US House of Representatives • Introduction of ADCs, mAbs, and Biologics platforms • American pharma companies to look for alternatives besides China 39

  41. Slide 41: Capacity expansion

    Expansion at current sites, Greater Noida & Bengaluru Expansion at new site, Devanahalli, Bengaluru Capacity : 1,000 FTE’s ( FY25 )  2,000 FTE’s ( FY26 )  4,000 FTE’s ( FY27 ) Total Capex USD 150 Mn. ( Expect RoCE > 20% ) 40

  42. Slide 42: Acquisition expanding TAM in mAbs and ADCs

    • Expanded TAM by USD 1.4 Bn. in mAbs and ADCs • Added strategic footprint in the EU • Enhanced domain expertise in ADC • Unique & cost-effective delivery model 41

  43. Slide 43: CDMO API revenue and EBITDA margin trajectory

    Revenue: 2x of FY24 EBITDA Margin: More than 15% Revenue: Rs. 663 Cr. Revenue: Rs. 645 Cr. EBITDA Margin: 5% EBITDA Margin: 10% FY23 FY24 FY30 42

  44. Slide 44: Grow CDMO API

    Growth driver: • Grow CDMO API • Further Strengthen CDMO: Leverage GMP manufacturing capabilities for Innovative New Chemical Entities • Custom Manufacturing: Partner with large pharma to manufacture products requiring life cycle management • China plus one strategy: Resilient supply chain through i

  45. Slide 45: Allergy Immunotherapy

    Allergy Immunotherapy Kyle Ferguson CEO – Allergy Immunotherapy 44

  46. Slide 46: Allergies, testing and treatment

    • 20% + global population have allergies e.g. Asthma and Allergenic Rhinits • Allergy Immunotherapy requires repeated shots of allergic antigens to develop immunity Allergies Testing Treatment 45

  47. Slide 47: Global allergy immunotherapy market growth drivers and trends

    Global Allergy Immunotherapy Market Growth Drivers and Trends USD Bn. • Concentrated US market with 3 players 3.0 • Complex supply chain from sourcing to processing 2.2 2.7 • Grandfathered approvals, new product needs BLA 2.0 0.2 0.3 • Market increasing in Sub-Lingual delivery 2023 2028 Non-US US •

  48. Slide 48: Venom extracts, allergenic extracts and skin testing devices

    nd • 100-year-old ‘HollisterStier’ brand • Onshore US FDA approved manufacturing • Sole Supplier of Venom extracts in the US • Dedicated sales force in the US • 200+ allergenic & 6 venom extracts • 2,000+ Allergists / ENTs as customers Venom Extracts Allergenic Extracts Skin Testing Devices Venom ex

  49. Slide 49: Allergy Immunotherapy revenue and EBITDA margin trajectory

    Revenue: ~1.5x of FY24 EBITDA Margin: 35% to 40% Revenue: Rs. 679 Cr. EBITDA Margin: 40% Revenue: Rs. 603 Cr. EBITDA Margin: 34% FY23 FY24 FY30 48

  50. Slide 50: Strengthen US position, grow outside US, increase R&D

    Strengthen competitive Grow outside US Increase investment position in US business in R&D • Retain and grow Venom • Develop new products & customers & patient base • Increase outside US technologies Venom sales through strategic partnerships in • Increase US revenue in • Build treatment European mar

  51. Slide 51: Generics

    Generics Dr Jaidev Rajpal CEO - Jubilant Generics

  52. Slide 52: Generics market growth drivers and trends

    Generics Market Growth Drivers and Trends USD Bn ~ 532 Developed Market 19 • US market to grow at 2%, signs of decrease in price reductions ~ 406 15 203 • Non-US market to grow by 5 - 7% 149 India Market 310 242 • India market to grow in excess of 8% • Brand building, in-clinic effectiveness of sale

  53. Slide 53: Non-US international, US and Indian markets

    Non-US international market • Broad therapeutic coverage - CVS, CNS, GI and multi specialty • 1 key markets with triple digit revenue in INR Cr., Build total of 3 - 4 markets (B2B2C) • Global presence in 50+ markets - US, Europe, Canada, Japan, Australia • CMO to few large branded generics customers

  54. Slide 54: Generics revenue and EBITDA margin trajectory

    Revenue : ~2x of FY24 EBITDA Margin : 15% to 17% Revenue : Rs. 729 Cr. EBITDA Margin : Breakeven Revenue : Rs. 775 Cr. Revenue : Rs. 762 Cr. EBITDA Margin : (18%) EBITDA Margin : (30%) FY23 FY24 TTM Dec'24 FY30 53

  55. Slide 55: Launch new products and grow non-US market

    Launch Grow the profitable Build branded new products Non-US international market business • Relaunch dormant ANDAs from • Launch 6 to 8 new products • Build presence in Diabetes, Roorkee and CMO network every year Dyslipidemia and Hypertension • Secure ANDAs (33) approvals • Scale 3 to 4 key market

  56. Slide 56: Proprietary Novel Drugs

    Proprietary Novel Drugs Dr Syed Kazmi CEO - Jubilant Therapeutics

  57. Slide 57: Precision oral medicines approach

    • Develop precision oral medicines with enhanced safety and therapeutic efficacy • Focused on specific set of patients, not responding to other therapies • Low-cost in-house discovery engine to generate drug candidates, validated through partnerships • Guided by world’s leading oncologists from Memo

  58. Slide 58: JBI-802

    • Company sponsored Phase II trial underway Blood Cancer • Highly differentiated for safety and efficacy than peers ET/MPN • Total Addressable Market in US: USD 3.3 Bn. • Investigator led trial under planning Lung Cancer JBI-802 NSCLC • Demonstrated clinical efficacy in two NSCLC patients in phase 1

  59. Slide 59: JBI-802 patient responses

    • Non small cell lung cancer patient progressed to last stage after immunotherapy. Post taking JBI-802 treatment, patient has been doing very well even after two years. Major symptoms have disappeared with confirmed partial response with ~40% tumor reduction • Over 50% shrinkage of the patient’s liv

  60. Slide 60: JBI-778

    Lung Cancer • Company sponsored First-in-human Phase I trial ongoing in India NSCLC with EGFR mutation • Total Addressable Market in US: USD 2.0 Bn. Brain Tumor • High unmet need with no effective treatment option JBI-778 HGG • Total Addressable Market in US: USD 1.7 Bn. Phase I trial underway Head

  61. Slide 61: Clinical data readouts and monetization

    • Expect clinical data readouts from CY 2025 to CY 2026 • Explore monetization through licensing or external fund raising 60

  62. Slide 62: Summary

    Summary Arvind Chokhany Group CFO, Whole-time Director

  63. Slide 63: Industry tailwinds, entry barriers, specialist management, risk management

    1 Supportive Industry tailwinds in Radiopharma, CDMO & CRDMO 2 High entry barriers or clear differentiation in each business 3 Specialist management to drive each business 4 Robust risk management with specific focus on quality & compliance 62

  64. Slide 64: Jubilant Pharmova stock return

    Jubilant Pharmova Limited Stock Return FY23 - FY24 - 9M’FY25 JPM - 169% NIFTY - 34% Apr-22 Jun-22 Sep-22 Dec-22 Mar-23 Jun-23 Sep-23 Dec-23 Mar-24 Jun-24 Sep-24 Dec-24 63

  65. Slide 65: Sustainability is at the core of our operations

    Sustainability is at the core of our operations Environment Social • 42% reduction1 in greenhouse gas emission • 23%+ women in global workforce • 23% reduction1 in specific water consumption • Assessment of new suppliers on sustainability • Zero Liquid Discharge at all Indian plants • 23,709 patient

  66. Slide 66: 2x revenue, 23-25% EBITDA margin, zero net debt by FY30

    Revenue Reach 2x from FY24 to FY30 EBITDA Margin 23% to 25% by FY30 Net Debt Zero by FY30 RoCE High Teens by FY30 65

  67. Slide 67: Thanks! We are open to questions

    Thanks! We are open to questions

  68. Slide 68: Abbreviations

    Abbreviation Details Abbreviation Details CVS Cardiovascular System MEA Middle East Africa CNS Central Nervous System LATAM Latin America CDMO Contract Development Manufacturing Organization LOE Loss of exclusivity CRDMO Contract Research & Development Manufacturing Organization FDA (US) U.S. Food a

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