Shinpoong Pharmaceutical Co., Ltd. · KRX:019170
Shinpoong Pharmaceutical — Fact Sheet (April 2018)
12 slides from Shinpoong Pharmaceutical's fact sheet, April 2018
Slide 1: Beyond Efficacy, Toward Patient
BEYOND EFFICACY, TOWARD PATIENT MAKING THE MOST OUT OF ACTS & EXTENDING THEIR LIFESPAN 180403_Pyramax_Key_Factsheet(12p-210x297)-final.indd 1 2018. 4. 3. 오전 11:13
Slide 2: Malaria Facing Emerging Challenges
UNMET NEEDS MALARIA FACING EMERGING CHALLENGES Antimalarial drug resistance is not the only cause of “treatment failure”[…] Incorrect dosing, incomplete adherence (compliance), poor drug quality, interactions with other drugs, compromised drug absorption, vomiting of the medicine, unusual pharmacoki
Slide 3: Pyramax: The Result of a Long-Term Partnership
UNMET NEEDS PYRAMAX® THE RESULT OF A LONG-TERM PARTNERSHIP PYRAMAX® Tablets and PYRAMAX® Granules for oral suspension are the result of a long-standing collaboration between Shin Poong Pharmaceutical and non-profit foundation Medicines for Malaria Venture (MMV) to develop a new, quality-assured arte
Slide 4: Consistent and Reliable Efficacy Over Long Term
EFFICACY PYRAMAX® CONSISTENT AND RELIABLE EFFICACY OVER LONG TERM EXCELLENT CURE RATES, SUSTAINED OVER TIME PCR-adjusted ACPR in the per-protocol population for the first treatment episodes by Pyramax® 99.8% 99.6% DAY 28 DAY 42 PCR-adjusted ACPR remains from 1st malaria episode at day 28 and day 42
Slide 5: Provides Long Term Protection with Less Reinfection
EFFICACY PROVIDES LONG TERM PROTECTION WITH LESS REINFECTION Crude (PCR-unadjusted) adequate clinical and parasitological response (ACPR) across all episodes at days 28 and 42 estimated using a general estimating equation (GEE), and between group comparisons (per-protocol population). DAY 28* DAY 42
Slide 6: Comparable Safety to Artemether/Lumefantrine
SAFETY PYRAMAX® COMPARABLE SAFETY TO ARTEMETHER/LUMEFANTRINE SIMILAR PROPORTION OF TREATMENT RELATED ADVERSE EVENTS BETWEEN PYRAMAX® AND AL AND BETWEEN THE EPISODES • Pyramax® has lowest risk of QTc prolongation • Pyramax® has higher liver enzymes rises rate but it is infrequent, without need for in
Slide 7: A Quality-Assured ACT
QUALITY PYRAMAX® A QUALITY-ASSURED ACT, NOW READY TO MAKE THE MOST OUT OF ACTs IN YOUR REGION Double-sided Approved by the EMA (Article 58) aluminium blister pack, stable in zone IV areas On The Global Fund List of Quality Assured Medicines On the WHO-Essential Medicines Lists Quality-assured, refer
Slide 8: Optimising Patient Adherence & Comfort
TOWARD PATIENT PYRAMAX® OPTIMISING PATIENT ADHERENCE & COMFORT BENEFITS TO PATIENTS PYRAMAX® AL DHA PQ ONCE-DAILY CHILD-FRIENDLY FORMULATION NO FOOD EFFECT EASIER TO COMPLETE the full treatment course PYRAMAX® GRANULES FOR ORAL SUSPENSION, ONCE WELL SUITED FOR INFANTS DAILY AND CHILDREN. FOR 3 DAYS
Slide 9: Adapted for Both Children & Adults
TOWARD PATIENT PYRAMAX® ADAPTED FOR BOTH CHILDREN & ADULTS ONCE-DAILY Can be taken with or without meals Child-friendly granules for oral suspension for children weighing 5-19kg Tablets for adults and children of 20kg+ RECOMMENDED RECOMMENDED DOSAGE DOSAGE Put the granule in a Stir gently until a Gi
Slide 10: The Most Efficient Solution for Patients and HCPs
TOWARD PATIENT PYRAMAX® THE MOST EFFICIENT SOLUTION FOR PATIENTS AND HCPs ● BOX OF 90 TABLETS WITH DISPENSING ENVELOPES ● 10 BLISTERS OF 9 TABLETS User-friendly packaging From hospital to home-based management ● BOX OF 90 SACHETS WITH DISPENSING ENVELOPES ● 30 STRIPS OF 3 SACHETS A dispensing envelo
Slide 11: Choose Pyramax: A New and Optimized ACT
CHOOSE PYRAMAX® A NEW AND OPTIMIZED ACT BEYOND EFFICACY TOWARD PATIENT GOES... ● Less re-infection of malaria ● Once daily ● Fast and long-term protection ● Child-friendly (taste masked) ● Quality assured by WHO-PQ & EMA ● No need for routine monitoring ● Potential to delay the onset ● Ensures optim
Slide 12: Prescribing information
Prescribing information NAME OF THE MEDICINAL PRODUCT and uncommonly, >10x ULN, with early onset peaking between Day 3 and 7 and normalising by Day 28. Pyramax 180 mg/60 mg Film-coated tablet Cases of syncope and isolated prolonged QTc were uncommonly reported for Pyramax. Mean decreases in heart ra