Beta Bionics, Inc. · NASDAQ:BBNX
Beta Bionics — Investor Presentation (2026)
74 slides from Beta Bionics's investor presentation, Aug 12, 2026
Slide 1: Ready, Set… GO BIONIC!
iLET BIONIC PANCREAS Ready, Set… GO BIONIC! MM000183 Rev D
Slide 2: Getting Started: Power On & Set Up
SECTION 1 Getting Started: Power On & Set Up MM000183 Rev D
Slide 3: Gather Supplies
Gather Supplies • Inset, Flex, or Contact Detach • iLet Cartridge Kit • iLet Connect Adapter • New vial of U-100 rapid acting insulin • Alcohol swabs • Continuous Glucose Monitor Or MM000183 Rev D
Slide 4: Charge Your iLet
Charge Your iLet ✓ Solid light on base ✓ Audible tone ✓ Percent charge displayed on iLet screen To maintain battery life: • Charge iLet daily (e.g., while disconnected for showering); can also charge while connected • It takes approximately 2 hours to charge a completely empty battery • Battery life
Slide 5: Download the iLet App
Download the iLet App MM000183 Rev D
Slide 6: Pair Your iLet Device with the iLet App
Pair Your iLet Device with the iLet App MM000183 Rev D
Slide 7: Check for Updates
Check for Updates MM000183 Rev D
Slide 8: Accept Clinic Invite
Accept Clinic Invite ✓ Report ✓ Accept Invitation ✓ Dismiss notification verifying acceptance MM000183 Rev D
Slide 9: Download the Bionic Circle App
Download the Bionic Circle App WARNING: Dosing decisions should not be made based on this device. The user should follow instructions on the iLet bionic pancreas system. This device is not intended to replace self-monitoring practices as advised by a physician. MM000183 Rev D
Slide 10: Invite Followers
Invite • Share glucose data and trend with up to 10 followers Followers • Pause and resume sharing MM000183 Rev D
Slide 11: Bionic Circle App – Customizing Alerts
Bionic • Turn on/off Circle App – • Set to critical alert or not (overrides silent mode/do not disturb) Customizing • Custom sounds Alerts • Custom delays MM000183 Rev D
Slide 12: Pairing Your CGM & BG Run Mode
SECTION 2 Pairing Your CGM & BG Run Mode MM000183 Rev A D
Slide 13: Pairing the iLet & Dexcom Sensor
Pairing the iLet & Dexcom Sensor ✓ Write down your sensor transmitter ID ✓ Shut down all other CGM medical devices ✓ Access the iLet Setup menu from your alert bell ✓ Tap on CGM Sensor -> Select your preferred CGM sensor -> Follow prompts Video: Replacing Your Dexcom G7 Video: Replacing Your Dexcom
Slide 14: Pairing the iLet & FreeStyle Libre 3 Plus Sensor
Pairing the iLet & FreeStyle Libre 3 Plus Sensor ✓ Start with a brand-new Libre 3 Plus sensor ✓ Access the iLet Setup menu from your alert bell ✓ Tap on CGM Sensor -> Select Abbott Libre 3 Plus -> Follow prompts Replacing your FreeStyle Libre 3 Plus Sensor Switching to FreeStyle Libre 3 Plus Sensor
Slide 15: Pairing the iLet & FreeStyle Libre 3 Plus Sensor
Pairing the iLet & FreeStyle Libre 3 Plus Sensor ✓ Go to More on the iLet App -> Tap CGM -> Start Sensor -> Follow prompts on phone MM000183 Rev D
Slide 16: Pairing the iLet & FreeStyle Libre 3 Plus Sensor
Pairing the iLet & FreeStyle Libre 3 Plus Sensor ✓ This icon will display on the iLet for first 12 hours after a Libre 3 Plus is connected ✓ Communicates that ✓ Confirm that the CGM sensors are not as Sensor is checked off accurate during this in the iLet Setup menu time ✓ The iLet algorithms are st
Slide 17: BG-Run Mode
BG-Run Mode • Reasons your iLet might go into BG-Run mode: • Failed CGM sensor/transmitter • Sensor is offline or disconnected (connection lost or sensor warm-up period) • Two choices in BG-Run mode: • Respond to iLet alerts by entering a fingerstick BG to continue dosing insulin until CGM values ar
Slide 18: CGM (Dexcom/Libre) vs BGM (Finger Stick)
CGM (Dexcom/Libre) vs BGM (Finger Stick) Fingerstick (blood glucose meter): Changes faster like the hiker in front ✓ Measures sugar directly in your blood at that exact moment ✓ Shows what your glucose is right now Continuous Glucose Monitor (Dexcom or Libre 3+): Changes slower like the hiker in bac
Slide 19: Transitioning to the iLet: How Is the iLet Different?
SECTION 3 Transitioning to the iLet: How Is the iLet Different than What I’m Doing Now? MM000183 Rev D
Slide 20: How the iLet Works
How the iLet Works No settings to manage – the iLet algorithms have it covered. MM000183 Rev D
Slide 21: How Is This Different than My Current Diabetes Care?
How Is This Different than My Current Diabetes Care? Right now, you and your The iLet does all of physician must calculate this for you Basal insulin Unlike long-acting insulin injections or Fully adaptive basal rates in an insulin pump High glucose correction insulin Using correction factors Meal A
Slide 22: How Insulin Pump Therapy Works
How Insulin Pump Therapy Works Rapid-Acting insulin only ✓ The pump uses rapid-acting insulin only ✓ In most cases long-acting insulin is NOT used ✓ Insulin is delivered in small amounts throughout the day Automatic adjustments ✓ When glucose is high → more insulin is delivered ✓ When glucose is fal
Slide 23: Factors that Affect BG
42 Factors that Affect BG Food Activity Biological Environmental Behavioral & Decision Making Medication MM000183 Rev D
Slide 24: Managing Highs and Lows
SECTION 4 Managing Highs and Lows MM000183 Rev D
Slide 25: iLet Alerts
Priority Screen Alert What to do iLet Alerts (Level) Inspect your cartridge, tubing, and infusion set for any leaks Medium or occlusions. Check for ketones and contact your High Glucose ✓ Alerts ON (Level 3) healthcare provider if your high glucose continues. ✓ Volume High ✓ Respond Quickly Your glu
Slide 26: Low Blood Sugar
Low Blood Sugar ✓ Remember! The iLet pauses insulin when blood sugar is dropping or is low. ✓ Keep the iLet volume set to a level you can hear. Use alerts on your smartphone in addition to the iLet. ✓ Treat to the Beep! Avoid taking carbs to treat low blood sugars too early. ✓ If you get a 2nd alert
Slide 27: How to Properly Treat a Low BG
How to Properly Treat a Low BG: Avoid Overtreating as This Can Cause Repeat Lows MM000183 Rev D
Slide 28: How to Properly Treat a Low BG
How to Properly Treat a low BG: Avoid Overtreating as This Can Cause Repeat Lows MM000183 Rev D
Slide 29: High Blood Sugar
High Blood Sugar • Be patient- It will take time for the iLet to learn your insulin needs. • High Glucose alert- Check ketones and follow the Ketone Action Plan. • Check your infusion site- When in doubt, change it out! • Long periods of high blood sugar can result in low blood sugar later- respond
Slide 30: Ketone Action Plan
Ketone Action Plan LA000059_C MM000183 Rev D
Slide 31: Keys to Success
Keys to Success ✓Device maintenance ✓Responding to alerts ✓Appropriate use of meal announcements MM000247_A MM000183 Rev D Imp ortant: the in fo rma tio n in this pres en ta tio n is co nf id en tia l an d pro prietary 31
Slide 32: Meal Announcements
SECTION 5 Meal Announcements MM000183 Rev D
Slide 33: Carbohydrate Containing Foods
Carbohydrate Containing Foods LA000062_B MM000183 Rev D
Slide 34: Low or No Carbohydrate Foods
Low or No Carbohydrate Foods LA000062_B MM000183 Rev D
Slide 35: Meal Announcing During Initial Learning Phase
Meal Announcing During Initial Learning Phase ✓ In the first few days, eat meals with carbs in your “Usual for me” range. ✓ Wait at least 4 hours before eating and announcing another meal. ✓ If needed, choose snacks with no carbs. MM000183 Rev D
Slide 36: Meal Announcement Tips
Meal Announcement Tips ✓ Announce right before first bite. ✓ Meal size is based on CARBOHYDRATES only. ✓ Do NOT announce if eating very low carb or no carbs at all. ✓ Do NOT announce more than 30 minutes after first bite. If you finished your plate, it’s too late! ✓ Announce snacks if the snack has
Slide 37: Meal Announcements
Meal Announcements Meal size guide: Carb Amount Example Usual for me This is the usual amount of carbs you Carb Amount would typically eat for that meal type. This is around 50% more carbs than More Carb Amount + your Usual for me meal (1.5 times as many carbs as your Usual for me meal). This is aro
Slide 38: Meal Announcements
Meal Announcements MM000183 Rev D
Slide 39: Meal Announcements
Meal Announcements MM000183 Rev D
Slide 40: Meal Announcements
Meal Announcements MM000183 Rev D
Slide 41: Exercise
SECTION 6 Exercise MM000183 Rev D
Slide 42: Exercise
Exercise To Connect or Disconnect? ✓ Okay to stay connected – the iLet is decreasing and increasing insulin in response to your CGM values. ✓ If you disconnect – disconnect up to one hour before exercise, or as recommended by your healthcare team ✓ Staying disconnected for too long or forgetting to
Slide 43: Cartridge & Infusion Set: Let’s Get Connected
SECTION 7 Cartridge & Infusion Set: Let’s Get Connected MM000183 Rev D
Slide 44: Infusion Set Site Selection
Infusion Set Site Selection Pick the right area Do use sites with some fatty tissue: • Abdomen (most common and reliable) • Upper buttocks / hips • Upper thighs • Back of arms (if you can reach or have help) Avoid problem spots Do not use sites: • Where clothing or belts rub a lot • Where you bend a
Slide 45: Infusion Site Rotation
Infusion Site Rotation • Move insulin pump infusion site to a new spot every 2–3 days (48–72 hours) to make sure insulin is being absorbed well • Do not reuse the exact same spot for at least 1-2 weeks • Keep new insertion sites at least 2 inches away from the previous site and at least 3 inches fro
Slide 46: Gather Supplies
Gather Supplies ✓ iLet Bionic Pancreas ✓ Cartridge ✓ Syringe ✓ Needle ✓ iLet Connector ✓ Infusion Set ✓ Insulin ✓ Alcohol Wipes MM000183 Rev D
Slide 47: Fill Your iLet Cartridge
Fill Your iLet Cartridge ✓ If using Fiasp PumpCart: Skip this step ✓ If using Novolog or Humalog: Follow the steps in this video to fill your iLet cartridge LA000060_K MM000183 Rev D
Slide 48: Prepare Your Infusion Set
Prepare Your Infusion Set Flex ✓ Inset Users: Follow the steps in this video ✓ Contact Detach Users: Follow the steps in this video ✓ Flex Users: Follow the steps in this video Inset Contact Detach MM000183 Rev D
Slide 49: M000223 Rev B MM000183 Rev D
Disconnect from your body at the site. Hold the adhesive tape in place by placing a finger justin front of the cannula housing, and gently squeeze the sides of the connector. Pull the connector needle straight out from the cannula housing. Failure to disconnect can result in } over delivery of insul
Slide 50: MM000223 Rev B MM000183 Rev D
Pull the syringe back to the ; Insert the syringe needle E : — 1.8ml mark. i 9 into the insulin vial. Fillthe syringe with insulin, Turn the syringe and vial over. Pull the syringe plunger back to fill the syringe to 1.8mlof U-100 rapid acting insulin. Remove the needle guard without touching the ne
Slide 51: MM000223 Rev B MM000183 Rev D
Fill the iLet cartridge with insulin. On theiLet tap the Insulin Swipe right “ Cartridge Icon. ; 1200PM s0=> on Rewind. & change cartridge (A) If the menu was entered from the low insulin alert, ! the iLet will automatically eee rewind. ty Insulin delivery will be stopped Place the cartridge upright
Slide 52: MM000223 Rev B MM000183 Rev D
Do not try to force the cartridge Into the ILet. Remove the old cartridge and Place the new filled cartridge tubing and discard. into the iLet. IF you feel resistance when inserting the cartridge, please go back to Step 11 and rewind the iLet. Never connect the tubing to the cartridge outside of the
Slide 53: MM000223 Rev B MM000183 Rev D
Attach NEW tubing by twisting into a NEW connector. Go to Fill Tubing DO NOT REUSE SUPPLIES. Tubing should NOT be connected to your body yet. Mivo00183 Rev D Attach NEW tubing by twisting into a NEW connector. Be sure the connection is straight and ti Beta Bionics
Slide 54: MM000223 Rev B MM000183 Rev D
15 Place connector in iLet. 12:00PM so= © Tap Go to Fill Tubing. 12:00PM © chan & change cartridge {ay ctor int ite cy a ‘ Insert the connector with the flat side facing the outside of the iLet. Push it in untilit is flat against the iLet. @ DO NOT REUSE SUPPLIES. Tubing should NOT be connected to y
Slide 55: MM000223 Rev B MM000183 Rev D
Press and Hold to fill tubing. 200 PM som si Tubing 0.0 units Hold urtl you seed 2:00PM ao Fil Tubing ¥# units (old unt you see drop: Continue to hold until you see drops of insulin dripping from the end of the new tubing. Contact Detach (must connect both Pieces of tubing first) iLet Flex Tap Yes w
Slide 56: MM000223 Rev B MM000183 Rev D
Insert your new infusion set and tap Next. 12:00 PM ao < Fitcannuia Insert your infusion set @ For help with this step, call Customer Support at 1-855-745-3800, Option 1 or scan the QR codes below for videos. MM000223 Rev B Fillthe cannula with insulin. 12:00 PM a0 (sill. cannula Teflon 6mm Select t
Slide 57: Let’s…
Let’s… SECTION 8.1 MM000183 Rev D
Slide 58: Enter Weight
Enter Weight 1. Ensure accurate weight is entered 2. GO BIONIC! MM000183 Rev D
Slide 59: Cartridge Replacement Failure
Cartridge Replacement Failure Failure to disconnect can result in over delivery of insulin. watch video here MM000224 MM000183 Rev D
Slide 60: Review Device Menus
SECTION 8.2 Review Device Menus MM000183 Rev D
Slide 61: Home Screen
Home Screen Status Bar Notifications View and respond to the alerts and reminders for your iLet device. Menu Access features like Enter BG, CGM, Settings, History, Mobile Glucose status Device, and Volume. View your current CGM value and trend arrow if available. The circle will spin when the iLet i
Slide 62: Home Screen
Home Screen LA000060_K MM000183 Rev D
Slide 63: Status Bar
Status Bar LA000060_K MM000183 Rev D
Slide 64: Menu Screen
Menu Screen LA000060_K MM000183 Rev D
Slide 65: Your job is not to figure out the amount of insulin you need
Your job is not to figure out the amount of insulin you need- that is the job of the iLet. MM000183 Rev D
Slide 66: Knowledge Checks
SECTION 9 Knowledge Checks MM000183 Rev D
Slide 67: Optimizing Your iLet Experience
Optimizing Your iLet Experience MM000183 Rev D
Slide 68: Knowledge Checks
Knowledge Checks 1. How can you recognize infusion set failure? 2. What should you hear from your iLet before treating a low blood sugar? 3. What should you do if you get a high alert that your glucose is >300mg/dL for 90 minutes? 4. What should you do if your glucose rises to 250mg/dL after a meal
Slide 69: Before Leaving: Safety Tips
SECTION 10 Before Leaving: Safety Tips MM000183 Rev D
Slide 70: Important Reminders
Important Reminders Infusion set and cartridge changes: CGM sensor replacement: • Change infusion set every 2 or 3 days. • Follow CGM manufacturer instructions for replacing CGM sensors. • Change cartridge, iLet Connector, and tubing at least every 3 days. • CGM values are used by the iLet to dose a
Slide 71: Always Have Extra Supplies
Always Have Extra Supplies Talk to your healthcare team about your backup therapy plan and the supplies you need. These may include: • Long-acting insulin pens or vials • Rapid-acting insulin pens or vials • Insulin pen needles or syringes • Insulin dosing plan MM000183 Rev D
Slide 72: Safety Considerations
Safety Considerations ✓ Avoid X-ray, MRI, CT, PET scan, radiation, extreme temperatures ✓ IPX8 (watertight for up to 12 feet for 30 minutes) ✓ Cleaning: Soft, lint-free cloth, damp with water or alcohol swab ✓ Asphyxiation risk associated with small parts ✓ Tips for travel ✓ Always keep iLet open an
Slide 73: Need Assistance?
SECTION 10 Need Assistance? MM000183 Rev D
Slide 74: Need Assistance?
Need Assistance? Call your healthcare team for questions Request replacement supplies from your CGM manufacturer if: about your: • You have a problem with the CGM sensor, transmitter or CGM app. • Diabetes • The sensor (and transmitter, if applicable) falls off or fails early. • BG control • Prescri