Spire Healthcare Group Plc · LSE:SPI
Spire Healthcare — Technical Presentation (March 2013)
17 slides from Spire Healthcare's technical presentation, Mar 9, 2013
Slide 1: Radiotherapy to the female pelvis
Radiotherapy to the female pelvis Dr Sherif Raouf MB BCh FRCR Consultant Clinical Oncologist BHRUT
Slide 2: How does radiotherapy works?
How does radiotherapy works? • Mechanism of action: radiation induce damage of tumour cell DNA, preventing cell division and causing cell death
Slide 3: Radiotherapy uses
Radiotherapy uses Curative indications: Cervical cancer 52% 5 yr OS. Bladder cancer Anal cancer Endometrial cancer Rectal cancer Palliative indications: Any tumour type for pain and symptom control
Slide 4: Procedure for giving radiotherapy
Procedure for giving radiotherapy Diagnosis Radiotherapy planning Treatment delivery
Slide 5: Radiotherapy planning
Radiotherapy planning • Patient positioning – Lasers – Tattoos – Immobilisation • To ensure reproducibility in a multi-fraction radiotherapy course
Slide 6: Positioning lasers
Spire Healthcare Covking after i aes
Slide 7: Radiotherapy side effects
Radiotherapy side effects Early (Acute): Occur during the course of the treatment Recover soon after the therapy is completed Late (chronic): late radiation complications are due to small vessel injury with endothelial damage, inflammation, fibrosis, ischaemia and necrosis. Occur months to years aft
Slide 8: Early Radiotherapy side effects
Early Radiotherapy side effects Fatigue Skin desquamation Diarrhoea Low blood count Frequency / cystitis
Slide 9: Skin desquamation
Skin desquamation ge, ! by
Slide 10: Late side effects
Late side effects • Skin telangectasia • Vaginal stenosis • Dilators • Late effects on bowels (proctitis) • Bladder changes • Avascular necrosis of the hip • Secondary cancer
Slide 11: Sexual morbidity
Sexual morbidity Sexual problems suffered by women with cervical cancer may include: loss of libido change in sexual activity and decreased orgasm. Up to 65% of women experience one or more of these problems due to vaginal dryness or bleeding. Vaginal stenosis and dyspareunia. atrophic vaginitis and
Slide 12: Skin telangectasia
Skin telangectasia S2 Spire Healthcare
Slide 13: Vaginal dilators
Vaginal dilators S2 Spire Healthcare
Slide 14: Sparing normal tissues is not an easy task
Sparing normal tissues is not an easy task
Slide 15: Intensity modulated radiotherapy (IMRT)
Intensity modulated radiotherapy (IMRT)
Slide 16: Using multiple fields allows for better sparing of normal tissues
Using multiple fields allows for better sparing of normal tissues
Slide 17: Summary
Summary • Radiotherapy is effective in treating pelvic cancers. • Acute radiotherapy side effects recover shortly after therapy ends. • Late effects tends be permanent and can take months to years to manifest. • New radiotherapy techniques allows for better tumour control with good sparing of normal
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