Boston Scientific Corporation · NYSE:BSX
Boston Scientific — Investor Presentation (April 2014)
15 slides from Boston Scientific's investor presentation, April 2014
Slide 1: Physician Health Talk: ED Treatment Options Beyond PDE-5 Inhibitors
PHYSICIAN HEALTH TALK: ED Treatment Options Beyond PDE-5 Inhibitors
Slide 2: Physician Presenter Disclaimer
Physician Presenter Disclaimer Products discussed in this presentation may be subject to regulatory approval / clearance and therefore labeling may change. Opinions given during this presentation are my personal, professional opinion. This lecture and demonstration is intended as a supplement to you
Slide 3: Why Are We Here?
Why Are We Here? • Goals • Understand your role of the health care provider in the treatment of Erectile Dysfunction (ED) • Understand ED treatment options beyond PDE-5 inhibitors • Understand the subspecialty of Prosthetic Urology
Slide 4: Erectile Dysfunction (ED)
Erectile Dysfunction (ED) What is it? • The inability to maintain an erection firm enough to have sexual intercourse How prevalent is it? • ~1 in 5 American men ≥20 years old1 • Over 30 million American men2 1. Selvin E, Burnett A, Platz E. Prevalence and risk factors for erectile dysfunction in the
Slide 5: Main Physical Causes of ED
Main Physical Causes of ED 3 3% 1% 5% 6% Vascular Diabetes Medication 15% 40% Pelvic Surgery or Trauma Neurological Causes Endocrine Problems 30% Other 3. Ridwan Shabsigh, MD, Tom F. Lue, MD. A Clinician’s Guide to ED Management. New York: Haymarket Media Inc.; 2006
Slide 6: ED: How Men Are Being Treated
ED: How Men Are Being Treated
Slide 7: Who Prescribes ED Medications?
Who Prescribes ED Medications?4 24% 28% 21% 27% 4. Brunk D. Erectile Dysfunction: 75% With Diagnosis Go Untreated http://www.practiceupdate.com/news/2452 2013
Slide 8: When PDE-5 Inhibitors Don't Work…
When PDE-5 Inhibitors Don’t Work… Patients who have failed a trial with phosphodiesterase type 5 (PDE5) inhibitor therapy should be informed of the benefits and risks of other therapies, including the use of5: • A different PDE5 inhibitor • Alprostadil intraurethral suppositories • Intracavernous dr
Slide 9: Vacuum Erection Device
Vacuum Erection Device 7 • Externally applied device mechanically effects penile blood engorgement • Cylinder/pump placed over penis creates closed chamber; pump slowly creates vacuum, drawing blood into corpora cavernosa • Constrictive elastic ring then placed (max 30 minutes) at base of penis to r
Slide 10: Intraurethral Alprostadil (MUSE)
Intraurethral Alprostadil (MUSE™†)10 • Alprostadil chemically identical to prostaglandin E1 • Vasodilatory effects increase blood flow to penis Product Characteristics • No needles or injections • Erection within 5 to 10 minutes • Must be refrigerated Adverse Events • Pain (penis, urethra or testes)
Slide 11: Intracavernous Injection Therapy
Intracavernous Injection Therapy 11 • Injected directly into corpora cavernosa Product Characteristics • On-set of erection within 5 to 20 minutes Adverse Events • Penile pain • Prolonged erection • Penile fibrosis • Injection site hematoma 11. Caverject® PI, Revised 08/2009.
Slide 12: Penile Implants
Penile Implants • On the market for over 40 years and over 300,000 implants have returned to a satisfying sex life14 • High patient and partner satisfaction rates reported in clinical studies12,13 • May offer a longer term treatment option to ED16 • 3-piece, 2-piece, and 1-piece (malleable) options
Slide 13: Patient Satisfaction with ED Treatments in One Clinical Study
Patient Satisfaction with ED Treatments in One Clinical Study17 Intracavernosa n=22 Injection Therapy Sildenafil n=31 Penile Implant n=32 Percentage of Patients Moderately or Completely Satisfied Rates of overall satisfaction using Erectile Dysfunction Inventory for Treatment Satisfaction (EDITS) qu
Slide 14: Why is it important to understand the subspecialty of prosthetic urology?
Why is it important to understand the subspecialty of prosthetic urology? • Not every urologist is a prosthetic urologist • A prosthetic urologist can offer the complete spectrum of treatment options • Not all urologists perform the penile implant procedure; prosthetic urologists have training and e
Slide 15: Questions?
QUESTIONS? ©2014 American Medical Systems, Inc. (“AMS”). The grant of permission to use AMS’s copyrighted material does not constitute endorsement by AMS of any persons, products, services, or organizations. ED-00951(1)/April 2014
Boston Scientific — Investor Presentation (April 2014) on 6ix