Trendlines Group Ltd. · SGX:42T
Trendlines — Limaca Medical — Series A Pitch Deck (2021)
13 slides from Trendlines's pitch deck, Dec 1, 2021
Slide 1: Better Biopsies for Enhanced Precision Medicine
A GAME CHANGER IN ENDOSCOPIC ULTRASOUND-GUIDED BIOPSY BETTER BIOPSIES FOR ENHANCED PRECISION MEDICINE SUMMER 2021 ASSAF KLEIN, CEO CARL RICKENBAUGH, CHAIRMAN OF THE BOARD
Slide 2: Disclaimer
DISCLAIMER IMPORTANT NOTICE This presentation includes certain statements and of an offer to buy, the Company’s securities in any This presentation has been prepared by Limaca estimates provided by the company with respect to jurisdiction. Neither this presentation nor anything Medical Ltd. (the “Co
Slide 3: Limaca's Precision EUS Biopsy Game Changer
LIMACA’S PRECISION™ ENDOSCOPIC ULTRASOUND GUIDED (EUS) BIOPSY GAME CHANGER IMPROVES DIAGNOSIS AND PROGNOSIS WHILE ADVANCING PATIENT-SPECIFIC TREATMENTS Improves Obtains larger Enables procedure Automated, diagnostic accuracy samples with higher with 1/10th electro-mechanical quality core tissue numb
Slide 4: Precision: A Leap in EUS Biopsy
PRECISION™: A LEAP IN EUS BIOPSY Manual 2-4 Passes with Time Poor Echo Imprecise User Dependent 30-50 Stabs Consuming Visualization Standard Poor Quality of Care Insufficient Samples Excellent Quality Precision Meets All Diagnostic by Limaca Testing Automated One Pass with Shorter Excellent Echo Pre
Slide 5: Over $1 Billion Market Opportunity
Over $1 BILLION MARKET OPPORTUNITY FOR LIMACA’S PRECISION EUS BIOPSY PLATFORM # OF RELEVANT MARKET PROCEDURES Pancreatic 850,000 Liver 225,000 Lung 200,000 TOTAL 1.275 million Sources: EUS Needles Market - Global Industry Analysis and Forecast, 2017 to 2025 by Transparency Market Research (TMR) Glob
Slide 6: Cancer Treatment Requires Precision Medicine
CANCER TREATMENT REQUIRES PRECISION MEDICINE Precision Treatment: Matches patient with best available treatment Genetic Profiling: Analyzes cancer DNA to define the genomic defect Genetic Profiling requires high quality tissue sample EVOLVING REQUIREMENTS OF PRECISION MEDICINE REQUIRES SIGNIFICANT I
Slide 7: 1st Indication: Pancreatic
1,000,000 biopsies performed annually 10% 9% Genetic testing CAGR 5-year Every tumor is different, survival rate requiring genetic profiling diagnosis 1ST INDICATION: PANCREATIC 25% 460,000 CANCER Recent studies suggest that 1 of every 4 pancreatic cancer new cases patients will benefit significantl
Slide 8: First-in-Human Clinical Study
FIRST-IN-HUMAN CLINICAL STUDY Enrolling in To date: Next stage: two leading centers 10 of 32 patients validate superiority in israel enrolled for genetic profiling Comparing Precision Safety & usability is excellent with 10X fewer stabs. to existing manual EUS Precision acquired large intact white c
Slide 9: Histopathology Quality Results
HISTOPATHOLOGY QUALITY RESULTS SharkCore Precision Sample acquired 10X more stabs with only three stabs Non-structural, diced tissue Contiguous and intact sample Adequate for cytology at the cellular level only Adequate for cytology, histopathology and genetic profiling
Slide 10: Regulatory and IP
REGULATORY AND IP IP R E G U L ATO R Y Endoscopic Biopsy Device: National phase FDA Class II, CE Class IIa, Reimbursement 510(k) pathway, submission will codes in place no clinical follow clinical study Tissue Penetrator: study required (confirmed by FDA) Provisional application
Slide 11: Experienced Team
EXPERIENCED TEAM Precision’s impact on endoscopic biopsy will play out similarly to what was seen in the past decade with breast biopsy IYAD KHAMAYSI MD ASSAF KLEIN CARL RICKENBAUGH FOUNDER & MED. DIRECTOR CEO CHAIRMAN OF THE BOARD procedures shifting from basic manual 20 years’ experience in medica
Slide 12: Milestones and Investment
MILESTONES AND INVESTMENT $ SAFE Round A Completed • Clinical Validation • Post Marketing Clinical Studies • Production Scale-Up • ISO and CE Approvals • FDA 510(k) Clearance • Commercialization • Second Product- Lung
Slide 13: Better Biopsies for Enhanced Precision Medicine
THE NEXT GENERATION IN ENDOSCOPIC ULTRASOUND GUIDED BIOPSY BETTER BIOPSIES FOR ENHANCED PRECISION MEDICINE ASSAF@LIMACA-MEDICAL.COM