Schrodinger, Inc. · NASDAQ:SDGR
Schrodinger — Technical Presentation (May 2026)
7 slides from Schrodinger's technical presentation, May 1, 2026
Slide 1: Teaching Protein-Ligand Complementarity using Schrödinger's Ligand Designer
Workshop #1 for Educator’s Week 2026 Teaching Protein-Ligand Complementarity using Schrödinger’s Ligand Designer Emma Kuczkowski & Kat Bay Education Team
Slide 2: Workshop Learning Objectives
Workshop Learning Objectives 1. Visualize and Quantify Molecular Complementarity • Utilize Interaction Maps and Real-time Scoring within the Ligand Designer interface to visually identify "hot spots" for H-bonding and hydrophobic interactions • Translate a 2D chemical structure into a 3D "fit" withi
Slide 3: Hands-on Demo
Hands-on Demo @ Schrédinger
Slide 4: Classroom Exercise Suggestions
Classroom Exercise Suggestions 1. The Steric Clash: Have students add a bulky t-butyl group into a tight pocket – Observation: The "Clash" icons (red disks) appear – Lesson: VSEPR theory and Van der Waals radii in 3D space 2. The H-Bond Matchmaker: Find a lone Carbonyl (C=O) on the protein backbone.
Slide 5: Alignment to Student Learning Outcomes from the American Chemical Society (ACS) Guidelines
Alignment to Student Learning Outcomes from the American Chemical Society (ACS) Guidelines 1. Macromolecules & Biological Chemistry (Section 5.1) ● ACS Requirement: Students should understand the structure and function of biological macromolecules ● Workshop Alignment: By using Ligand Designer, stud
Slide 6: Alignment to Student Learning Outcomes from the American Society for Biochemistry and Molecular Biology (ASBMB) Guidelines
Alignment to Student Learning Outcomes from the American Society for Biochemistry and Molecular Biology (ASBMB) Guidelines 1. Macromolecular Structure, Function, and Regulation ● ASBMB Standard: Students should understand that "Structure is determined by environmental factors and the cumulative effe
Slide 7: Thank you for attending!
Thank you for attending! Please join us for more free workshops this week: ● Mapping the Reaction "Mountain Pass" and Visualizing Transition States with Schrödinger’s AutoTS Workflow: Wed. April 29th from 11-11:30am ET ○ Great for educators teaching physical chemistry, organic chemistry, etc. ● Sear