Bioforce Nanosciences Holdings, Inc. · OTC:BFNH
Bioforce Nanosciences — Investor Presentation (January 2009)
26 slides from Bioforce Nanosciences's investor presentation, Jan 15, 2009
Slide 1: BioForce Nanosciences Holdings, Inc.
BIOFORCE BioForce Nanosciences Holdings, Inc. BFNH.OB www.bioforcenano.com - (515) 233-8333
Slide 2: Safe Harbor Statement Under the Private Securities Litigation Reform Act
BigP oGe Safe Harbor — eal Statement Under the Private Securities Litigation Reform Act t) The written and verbal versions of this presentation contain forward- lponing statements. These statements may address projections of our future financial performance, product and operation developments, accep
Slide 3: Introduction
eiaPGRee Introduction BioForce is a nanotechnology company utilizing its ultra- micro to nano scale fluid deposition platform to deliver products and solutions for researchers and commercial users. www.bioforcenano.com - (515) 233-8333
Slide 4: BioForce Platform Technology
BloFORCE Platform Technology *Fluid deposition in picoliter (10-'2) to attoliter (10-18) volumes (0.50 — 60.0 micron spot sizes) «Embodiments of this are BioForce’s Nano eNabler™ and Cyto eNabler™ systems «Customers using the Nano eNabler include cell biology laboratories, biosensor developers, and
Slide 5: The eNabler Systems
piororce The eNabler™ Systems Nano eNabler™ and Cyto eNabler™ ¢ Benchtop molecular printers * Deposit fluids onto solid surfaces in tiny quantities ¢ Software driven ¢ Flexible, enables multiplexing www.bioforcenano.com - (515) 233-8333
Slide 6: The eNabler Systems: Surface Patterning Tools
Bioforce The eNabler™ Systems Surface Patterning Tools™ (SPTs) ¢ Fill well with fluid Reservoir supporting Substrate (biological material, SS Cantilever inks, polymers, etc.) Microchanne! BR 7 opening ap ¢ Fluid travels down channel ¢ SPT touched to surface creates spot ¢ SPTs available with up to s
Slide 7: Patterned Surfaces
siororce Patterned Surfaces The eNablers are typically used to create what are known as Patterned Surfaces www.bioforcenano.com - (515) 233-8333
Slide 8: Cell Biology Applications
sioroRce Cell Biology Applications Tissue Engineering Cancer Cell Biology Live Cell Assays Living cells on a heart-shaped Cancer cell adhesion study on Controlled formation of living cell biomimetic surface created with protein array created withthe Nano — “spheroids” on a biomimetic array the Nano
Slide 9: Biosensor Applications
BIOFORCE I NANOSCIENCES Virus Detection Anti-virus antibodies printed on a novel membrane sensor using the Nano eNabler™ System, Image courtesy Dr. Jan Hoh, Johns Hopkins University. Biosensor Applications o< Novel Diagnostic Devices Antibodies printed on an AFM cantilever as a __ prototype biosenso
Slide 10: Non-Biological Applications
g a Non-Biological Applications Patterning of conductive polymers or metal inks to create circuits ¢ BioForce customers in Korea and Japan doing this ¢ Testing of multiple circuit designs at no additional cost vs. photolithography requiring new mask per iteration UV-curable ink for individual pixel
Slide 11: Competitive Landscape
eiproRre Competitive Landscape Product Reduced Reliability | Multiplexing | 1 to 20 ym Biological Features Clogging Compatibility eNabler Systems Micro-contact printing (PDMS) Nanopipettes AFM nanolithography Ink-jet printing www.bioforcenano.com - (515) 233-8333
Slide 12: eNabler User Examples
eiproRre eNabler™ User Examples Biological Applications STANFORD SCHOOL OF MEDICINE * Stem Cell Biology * Cancer Cell Biology Medical Sciences * Tissue Engineering * Biosensors | ] | i 7 * Neurobiology HARVARD MEDICINE ERSITE * Printing of circuits pups Cue Non-biological Application www.bioforcenan
Slide 13: Customer Base
gear Customer Base Cumulative eNabler System Sales B International B Domestic 0+ Q4 Qt Q@ 8 G4 QI Q2 BB @& A Q @ 2005 2006 2006 2006 2006 2007 2007 2007 2007 2008 2008 2008 2008
Slide 14: eNabler Evolution
BIOFORCE eNabler™ Evolution eNabler Systems will evolve into production tools for patterned surface products requiring high volume manufacture (e.g., diagnostics) www.bioforcenano.com - (515) 233-8333
Slide 15: Customer Applications
g a Customer Applications BioForce enhances eNabler System value via: Collaboration Agreements * University Pierre & Marie Curie * SUNY Albany ¢ Arizona State University + lowa State University ¢ U. Minn./St. Thomas U. Rights of First Refusal * Georgia Tech * UC San Francisco Practical Cooperation —
Slide 16: BIOFORCE
BIOFORCE * Non-destructive pathogen detection and identification * Fast, portable, multiple tests on one chip ¢ Bio-defense and environmental applications * $1.6 million of funding in 2009 U.S. Department of Defense budget www.bioforcenano.com - (515) 233-8333
Slide 17: IP Position
aSF Rae IP Position * Patent on the Nano eNabler™ * Patent pending on Surface Patterning Tools (SPTs™) ¢ Patent on ViriChip™ Patent on Protein Nanoarrays Patent on Chip-on-a-Tip™ Patent on Sindex™ Chip Additional patents issued and pending www.bioforcenano.com - (515) 233-8333
Slide 18: Opportunities
sioroRce Opportunities The Cyto eNabler™ and Nano eNabler™ Systems open the door to many near and long term opportunities. Instruments * Research — biological and non-biological * Production - biological and non-biological Patterned Surfaces * Custom ¢ Standard Scientific Applications ¢ BioForce R&D
Slide 19: Sources of Revenues
Sjaronee Sources of Revenues Y ° Instrument sales: in place Y °*Consumables (SPTs and Sindex chips): in place Y ° Service contracts: in place Y ° Patterned surfaces: in place ¢ Scientific applications licenses & royalties: www.bioforcenano.com - (515) 233-8333
Slide 20: Estimated Market Sizes
g tala Estimated Market Sizes * Academic research — biological = $300M in total for instruments + $25M annually in consumables and support + Industrial — biological = $1B in total for instruments + $250M annually in consumables and support + Patterned surfaces — biological = $125M annually * ViriChi
Slide 21: Management
gee Management Kerry Frey, President and Chief Executive Officer * 30 years management and operations experience in medical devices, pharmaceuticals and healthcare * 20 years Johnson & Johnson, including VP of Sales and Marketing for Hospital Services * Experience with multiple start-up companies Gr
Slide 22: Background and History
siororce Background and History Conducted grant funded scientific research (1994 - 2000) Installed initial Nano eNabler at Johns Hopkins (2005) First Nano eNabler sales to Russian Academy of Biomedical Sciences and Harvard Medical School (2006) Placement of 20 Nano eNabler units at leading academic
Slide 23: Financing History
siororce Financing History * 1995 — 2008: $6.2 million of governmental grant funding * 2001 — 2005: Venture capital investments totaling $4.0 million ($3.5 million from European investment firm) * 2006: Reverse merger into public shell concurrent with $6.0 million equity investment * 2007: $1.0 mill
Slide 24: Financial Results
aSF Rae Financial Results H1 2007 H2 2007 H1 2008 Revenues $ 543,566 $ 581,463 $ 645,290 Gross profit $ 230,835 $ 318,641 $ 244,759 Cash operating loss $ (1,328,602) $ (1,122,829) $ (1,148,930) Significantly lower cash operating loss anticipated for H2 2008. www.bioforcenano.com - (515) 233-8333
Slide 25: Drivers of Growth
sioroRce Drivers of Growth * Scientific publications from eNabler users o Recent MIT paper an example of this o Drive academic research demand o Stimulate commercial interest * Commercial partnerships - sales + R&D Increased direct sales capabilities Increased distributor familiarity with product At
Slide 26: Investment Summary
nig ORGE Investment Summary * Platform technology with application in biological and non-biological areas * Established market presence through user base of top tier research institutions * Multiple revenue streams — instruments (research & commercial), patterned surfaces, consumables, service contr
BioForce Nanosciences Holdings — Investor Presentation (January 2009) on 6ix