Novocure Limited · NASDAQ:NVCR

Novocure — Q3 2025 Earnings Presentation

11 slides from Novocure's earnings presentation, Oct 30, 2025

  1. Slide 1: Novocure Q3 2025 earnings

    Novocure Q3 2025 earnings Thursday, October 30, 2025 Confidential © 2024 Novocu © 2025 re GmbH Novocu re GmbH 1

  2. Slide 2: Forward-looking statements

    forward - looking statements In addition to historical facts or statements of current condition, this presentation may contain forward - looking statements. Fo rward - looking statements provide Novocure’s current expectations or forecasts of future events. These may include statements regarding ant

  3. Slide 3: 2025 key objectives, unlocking TTFields potential

    2025 key objectives, unlocking TTFields potential DRIVING COMMERCIAL ADVANCING DELIVERING ADOPTION CLINICAL PIPELINE PRODUCT INNOVATION ✓ NSCLC drive global active ✓PANOVA - 3 data presented ✓Launch MyNovocure patient growth and pursue and published patient app reimbursement ✓PANOVA - 3 marketing ✓N

  4. Slide 4: Q3 financial and operational updates

    q3 financial and operational updates Consistent commercial, clinical and regulatory execution • Quarterly net revenues of $167 million , +8% year - over - year • Record 4,416 active patients on therapy, +7% year - over - year (GBM +5% year - over - year) • 109 NSCLC prescriptions received, 100 NSCLC

  5. Slide 5: Q3 NSCLC launch results by the numbers

    q3 NSCLC launch results by the numbers GLOBAL NSCLC PRESCRIPTIONS RECEIVED PHYSICIAN PROFILE PATIENT PROFILE THERAPY TIMING PRESCRIBER BREADTH CONCOMITANT THERAPY QUICK STARTS 109 84 unique prescribers 59% / 41% split between concomitant 23 - day average time between prescription ICI or docetaxel an

  6. Slide 6: Positive outcomes across multiple solid tumor indications

    positive outcomes across multiple solid tumor indications non - small cell brain mets locally advanced glioblastoma lung cancer from NSCLC pancreatic cancer 1.0 HR = 0.63 HR = 0.74 HR = 0.72 HR = 0.82 P- value < 0.001 P- value = 0.035 0.8 P- value = 0.044 P- value = 0.039 Probability of intracranial

  7. Slide 7: Q3 2025 select financials

    q3 2025 select financials U.S. DOLLARS IN MILLIONS Q3 2025 Q3 2024 Net revenues $ 167.2 $ 155.1 Cost of revenues 44.7 35.4 Gross profit 122.5 119.7 Research, development and clinical expenses 54.0 51.9 Sales and marketing 58.5 59.8 General and administrative 45.9 40.1 Total operating costs and expen

  8. Slide 8: Together with our patients, we strive to extend survival in some of the most aggressive forms of cancer

    together with our patients, we strive to extend survival in some of the most aggressive forms of cancer Confidential © 2024 Novocu © 2025 re GmbH Novocu re GmbH 8

  9. Slide 9: Adjusted EBITDA reconciliation

    adjusted EBITDA reconciliation Adjusted EBITDA is a non - GAAP measurement of earnings before interest, taxes, depreciation, amortization and share - based compens ation. We believe Adjusted EBITDA is useful to investors in evaluating our operating performance because it helps investors compare the

  10. Slide 10: Optune Lua and Optune Gio indications for use and important safety information

    Optune Lua ® and Optune Gio ® indications for use and important safety information INDICATIONS • Optune Lua ® is indicated as a treatment concurrent with PD - 1/PD - L1 inhibitors or docetaxel for adult patients with metastatic non - small cell lung cancer ( mNSCLC ) who have progressed on or after

  11. Slide 11: Optune Lua and Optune Gio indications for use and important safety information

    Optune Lua ® and Optune Gio ® indications for use and important safety information WARNINGS AND PRECAUTIONS • Optune Lua and Optune Gio can only be prescribed by a healthcare provider that has completed the required certification training provided by Novocu re ® (the device manufacturer). • Do not p

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