Alkermes Plc · NASDAQ:ALKS

Alkermes — Q4 2024 Earnings Presentation

21 slides from Alkermes's earnings presentation, Feb 12, 2025

  1. Slide 1: Fourth Quarter and Year-End 2024 Financial Results & Business Update

    Fourth Quarter and Year-End 2024 Financial Results & Business Update February 12, 2025 Exhibit 99.2

  2. Slide 2: Forward-Looking Statements and Non-GAAP Financial Information

    Forward-Looking Statements and Non-GAAP Financial Information Certain statements set forth in this presentation constitute “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, but not limited to, statements concerning: Alkerm

  3. Slide 3: Highly Profitable, Self-Funding Business With Strong Balance Sheet

    Highly Profitable, Self-Funding Business With Strong Balance Sheet EBITDA represents earnings before interest, tax, depreciation and amortization; earnings include share-based compensation expense. * Reconciliation of this non-GAAP financial measure to the most directly comparable GAAP financial mea

  4. Slide 4: Q4 & FY 2024 Financial and Operational Performance

    Q4 & FY 2024 Financial and Operational Performance

  5. Slide 5: FY 2024 Financial Results Summary

    In millions FY 2024 Financial Results Summary Total Revenue In millions GAAP Net Income GAAP Earnings Per Share Diluted FY 2024 results reflect expiration of royalty on U.S. net sales of INVEGA SUSTENNA® in August 2024. FY 2023 results reflect reinstatement of certain U.S. royalties following the su

  6. Slide 6: FY 2024 Profitability From Continuing Operations

    In millions FY 2024 Profitability From Continuing Operations GAAP Net Income From Continuing Operations In millions Non-GAAP Net Income* From Continuing Operations EBITDA* From Continuing Operations In millions EBITDA represents earnings before interest, tax, depreciation and amortization; earnings

  7. Slide 7: Q4 2024 Revenue Summary

    Q4 2024 Revenue Summary In millions Q4’24 Q4’23 Total Proprietary Net Sales $307.7 $242.0 VIVITROL® $134.1 $102.4 ARISTADA®* $96.6 $83.4 LYBALVI® $77.0 $56.2 Manufacturing & Royalty Revenue $122.3 $135.5 Total Revenue $430.0 $377.5 *Inclusive of ARISTADA INITIO® **Reflects expiration of royalty on U

  8. Slide 8: FY 2024 Revenue Summary

    FY 2024 Revenue Summary In millions FY’24 FY’23 Total Proprietary Net Sales $1,083.5 $920.0 VIVITROL® $457.3 $400.4 ARISTADA®* $346.2 $327.7 LYBALVI® $280.0 $191.9 Manufacturing & Royalty Revenue $474.1 $743.4*** Total Revenue $1,557.6 $1,663.4*** *Inclusive of ARISTADA INITIO® **Reflects expiration

  9. Slide 9: Alkermes: 2025 Financial Expectations

    Alkermes: 2025 Financial Expectations* *These expectations are provided by the Company on Feb. 12, 2025 and are effective only as of such date. The Company expressly disclaims any obligation to update or reaffirm these expectations. ‡Reconciliation of this non-GAAP financial measure to the most dire

  10. Slide 10: 2024 Commercial Review

    2024 Commercial Review

  11. Slide 11: Topline Growth and Diversification Reflect Evolving Business

    Topline Growth and Diversification Reflect Evolving Business *Inclusive of ARISTADA INITIO® **Licensed product (royalty & manufacturing revenue) Key Product Revenues ($M) $574 $715 $893 $1,049 $1,218

  12. Slide 12: LYBALVI Performance and Expectations

    LYBALVI® Performance and Expectations *These expectations are provided by the Company on Feb. 12, 2025 and are effective only as of such date. The Company expressly disclaims any obligation to update or reaffirm these expectations. LYBALVI Quarterly Net Sales ($M) Q4’24 LYBALVI net sales of $77.0M r

  13. Slide 13: LYBALVI Prescription Growth Trends

    LYBALVI® Prescription Growth Trends Q4’24 total TRx: ~60,300 reflecting 5% sequential growth compared to Q3’24 *Source: IQVIA NPA Weekly Post-Launch TRx* (Through 1/31/2025) TRx Week

  14. Slide 14: ARISTADA Performance and Expectations

    ARISTADA® Performance and Expectations ARISTADA Quarterly Net Sales* ($M) Q4’24 ARISTADA net sales were $96.6M FY’24 ARISTADA net sales were $346.2M Outlook: FY’25 net sales expected to range from $335M – $355M†* *Inclusive of ARISTADA INITIO® †These expectations are provided by the Company on Feb.

  15. Slide 15: VIVITROL Performance and Expectations

    VIVITROL® Performance and Expectations VIVITROL Quarterly Net Sales ($M) *These expectations are provided by the Company on Feb. 12, 2025 and are effective only as of such date. The Company expressly disclaims any obligation to update or reaffirm these expectations. Q4’24 VIVITROL net sales were $13

  16. Slide 16: Appendix

    Appendix

  17. Slide 17: Appendix: Amounts Included in Discontinued Operations

    Appendix: Amounts Included in Discontinued Operations (In millions) Year Ended December 31, 2023 Three Months Ended March 31, 2024 Three Months Ended June 30, 2024 Three Months Ended September 30, 2024 Three Months Ended December 31, 2024 Year Ended December 31, 2024 Cost of goods manufactured and s

  18. Slide 18: Appendix: Financial Results GAAP to EBITDA Adjustments

    Appendix: Financial Results GAAP to EBITDA Adjustments (In millions) Year Ended December 31, 2024 Year Ended December 31, 2023 Net Income from Continuing Operations — GAAP $ 372.1 $ 519.2 Adjustments: Depreciation expense 27.4 36.9 Amortization expense 1.1 35.7 Interest income (42.5) (30.9) Interest

  19. Slide 19: Appendix: Financial Results GAAP to Non-GAAP Adjustments

    Appendix: Financial Results GAAP to Non-GAAP Adjustments (In millions) Year Ended December 31, 2024 Year Ended December 31, 2023 Net Income from Continuing Operations — GAAP $ 372.1 $ 519.2 Adjustments: Share-based compensation expense 96.6 92.7 Depreciation expense 27.4 36.9 Amortization expense 1.

  20. Slide 20: Appendix: 2025 Guidance GAAP to EBITDA and Adjusted EBITDA

    Appendix: 2025 Guidance GAAP to EBITDA and Adjusted EBITDA Projected GAAP and non-GAAP measures reflect the mid-points within the Company’s financial expectations ranges. (In millions) Year Ended December 31, 2023 Year Ending December 31, 2025 Projected Net Income — GAAP $ 190.0 Adjustments: Net int

  21. Slide 21: (© 2025 Alkermes. All rights reserved.

    www.alkermes.com (© 2025 Alkermes. All rights reserved.

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