Slide 1: The Future of Breeding: Company Introduction April 2023
Exhibit 99.1 The Future of Breeding ™ Company Introduction April 2023
Slide 2: Bill Gates quote on seed innovation and food security
“Investing in seed innovation is one of the best ways to ensure food security.” - Bill Gates 2 2
Slide 3: Key Management Team
Key Management Team Rory Riggs Greg Gocal, PhD Peter Beetham, PhD CHIEF SCIENTIFIC OFFICER CHIEF EXECUTIVE CHIEF OPERATING OFFICER EXECUTIVE VICE PRESIDENT OFFICER PRESIDENT CHAIRMAN CO-FOUNDER CO-FOUNDER CO-FOUNDER Noel Sauer, PhD Wade King, MD Rosa Cheuk Kim, JD SENIOR VICE PRESIDENT CHIEF FINANCI
Slide 4: Background: Plant Genetics Business
is in the Background Plant Genetics Business FOUNDED EMPLOYEES 2001 ~200 HEADQUARTERS Products San Diego, CA 1) Plant traits in Major Crops Productivity traits that make crops more adaptable to the environment, have increased yields or require less chemicals. Crop Focus 2) Sustainable Ingredients -
Slide 5: Merger Combines Key Technologies in Gene Editing
See: Cibus.com for Announcement & Details https://www.Cibus.com/press-release.php Merger Combines Key Technologies in Gene Editing Productivity Traits Sustainable Ingredients Gene Edited Plants Plants, Micro-Organisms Oil Seeds Cereals Yarrowia Plant Cell Matrix (Both) (Both) (Cibus) (Calyxt) 5
Slide 6: The Trait Machine - Revolutionary Breeding Platform
Technology & Business The Trait Machine™ - Revolutionary Breeding Platform 1- Changes Scale, Speed & Accuracy 2- Changes Opportunity Set - Disease, Nitrogen Use, Climate Change 6
Slide 7: RTDS Non-GMO Gene Editing vs GMO Trait Technology
Foreign DNA / Gene Edit RTDS® Transgene Insertion Cibus RTDS Trait Technology Proprietary Non-GMO GMO Trait Technology Genetic Modification w/o Gene Editing Platform Genetic Modification integrating integrating Foreign DNA/Transgene Foreign DNA/Transgene Traits are Conventional Breeding-like” PROCES
Slide 8: RTDS Transforms Breeding
RTDS Transforms Breeding An Industrial Scale End-to-End Semi-Automated Gene Editing (Breeding) Process “Nature Identical” Traits Traits from Trait Machine that “Step Change in Breeding” are conventional breeding like. Bio-Mfg. Standards Pharma Standard Quality Control & Assurance. RTDS 8
Slide 9: Step Change Occurs Two Ways
Step Change Occurs Two Ways 1– Prototyping: Accelerates Development & Proof of Concept 2– Production: Accelerates Speed to Market. Trait Machine Trait Machine directly Once a trait is developed, Trait Machine accelerates edits a customer’s accelerates prototyping or time to commercialization. testin
Slide 10: Regulatory is Driving this Future
Regulatory is Driving this Future Global Push to Regulate Gene Editing Similar to Conventional Breeding Where Policy is in Place, Trait Machine is Regulated Similar to Breeding The EU is a Key Driver - The European Union has announced that on June 7, they will release their proposals for new gene ed
Slide 11: Business Model: Traits Distributed in Seeds by Seed Cos
Business Model: Traits Distributed in Seeds by Seed Co’s Seed Companies in-license productivity traits and pay trait royalties E.G.: In 2018, Corteva disclosed that they pay ~$750 million in Trait Royalties.(*) WHO TURN TO TURN TO Farmers Seed Companies Plant Trait Developers Challenged by the impac
Slide 12: Economics: Seed Cos Pay Royalties for Traits
Economics: Seed Co’s Pay Royalties for Traits Royalties (Trait Fees) based on “Value Per Acre” Trait Fees NA&SA Trait Market $2.1B Soybean Ø Accessible Acres ~400 MM $1.0B Cotton Major Crops Ø Trait Fee Acres 2020 Est. > 300 MM Trait Fees (NA&SA) $0.4B Ø Avg. Trait Fee/Acre by Crop Canola Current Ma
Slide 13: Product Review Pipeline
Product Review Pipeline 3- Developed Products 2- Advanced Products 1- Beginning Development 13
Slide 14: Initial Commercial Model: Canola, Rice, Soybean
Initial Commercial Model: 3 Crops: Canola, Rice, Soybean (~ 250 MM Acres) Pipeline of 6 Trait Products Cibus Operates as an Extension of Partner’s Breeding Program Rice Soybean SCa oyno bela an MM MM MM TAM TAM TAM ACRES 11 ACRES 190 ACRES 46 NOTE: TAM - Total Addressable Market includes just hybrid
Slide 15: The Pipeline
The Pipeline EST. CIBUS TRAIT ACRES Broad Pipeline Applied Initially to Canola, Rice & Soybean* Trait Machine enables serving same trait to multiple crops, customers SPECIALTY TRAITS ~30 MM Four of the Six Traits have Applicability for Multiple Crops * Acres based on Canola, Rice, Soybean in N.A.,S.
Slide 16: Developed Traits are Being Launched
Developed Traits are Being Launched st 1 Crops: Canola & Rice Ø Cibus already has 10 PSR customers and 1 Rice customer. - Transfers of edited elite germplasms started in Q1 2023. Ø All 3 have been determined not to be regulated articles through USDA APHIS “Am I Regulated” (now the SECURE Process) fo
Slide 17: Lead Trait: PSR
Lead Trait: PSR Pod Shatter Reduction (PSR) - Canola/WOSR Quantifiable Savings & Pricing, Recently Issued Product Patent* Commercial Progress: POD Shatter Reduction Developed & Transferring Sheaths or pods shatter in rain/high winds, causing yield Collaborations. losses of 10% or more. 10 Transfers
Slide 18: Advanced Traits Address Multiple Crops
Advanced Traits Address Multiple Crops Both Sclerotinia and HT2 are Estimated to be 80+ MM acre crops. Both have been determined not to be regulated articles through USDA APHIS “Am I Regulated” (now the SECURE Process) for regulating gene edited products Note: See slide 23 for sources & assumptions.
Slide 19: Market is 2x with Corn & Wheat
Market is 2x with Corn & Wheat* Timeline: Corn and Wheat Trait Machine Platform Expected by 2025. Two Pipeline Traits are Directly Applicable to Corn & Wheat. Trait Fee Acres for Each Trait is Estimated to Exceed 100 Million Acres. EST. CIBUS TRAIT ACRES * Acres based on Corn and Wheat in N.A..,S.A.
Slide 20: Crop Strategy: Multiple Traits for Each Crop
Crop Strategy: Multiple Traits for Each Crops Strategy: Crop Platforms with a Pipeline of Stacked Traits Available to Each Customer Multiple Traits Means Increased Royalty bearing Trait Acres for a Specific Crop Cibus has a Multi-Trait Pipeline for Canola Est. Cibus Trait Acres* Est. Trait Royalty*
Slide 21: Business Strategy
Business Strategy: Ø Build Trait Machine Crop Platforms for all Major Crops Ø Build Family of Important Traits Applicable to Individual Crops and Across Multiple Crops Trait Fees $2.1B Soybean The Underlying Scale of Traits Major Crops $1.0B NA&SA Ø Major Traits are Applicable Cotton ~400 MM Acres 2
Slide 22: Huge Economic Opportunity
Huge Economic Opportunity 1) Many Multi-Crop Trait Target Mkts from 50 to 300MM Acres 2) Many Major Trait Fee Opportunities from $5 to $30 per Acres 3) Many Product Opportunities to Replace Major Commodities Target Areas Sustainable Ingredients Resistance Traits Efficiency Traits PLANT OUTPUTS Renew
Slide 23: Disclaimer
Disclaimer Securities Law Matters Acreage Data This presentation has been prepared by Cibus Global, LLC (the Company ), and the Company is This presentation has 2 available acreage calculations: TAM-Total Accessible Acres and Trait responsible for its contents. It shall not constitute an offer, nor