Merck & Company, Inc. · NYSE:MRK

Merck & — Investor Day (2019)

15 slides from Merck &'s investor day presentation, 2019

  1. Slide 1: Welcome & Introductions

    Welcome & Introductions Ken Frazier, Chairman and Chief Executive Officer Financial & Value Creation Overview Rob Davis, Chief Financial Officer and Head of Global Services Commercial Growth Drivers: KEYTRUDA & Beyond Frank Clyburn, Chief Commercial Officer Animal Health Innovation Rick DeLuca, Pres

  2. Slide 2: Forward-Looking Statement

    FORWARD-LOOKING STATEMENT OF MERCK & Co., Inc., Kenilworth, N.J., USA These presentations from Merck & Co., Inc., Kenilworth, N.J., USA (the “company”) include “forward- looking statements” within the meaning of the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995.

  3. Slide 3: Commercial Priorities to Drive Further Global Growth

    COMMERCIAL PRIORITIES TO DRIVE FURTHER GLOBAL GROWTH Frank Clyburn Build on leading Capitalize on Successfully position across key global growth execute new growth pillars opportunities launches 17

  4. Slide 4: Current Pillars Have Expansion Opportunities Ahead

    CURRENT PILLARS HAVE EXPANSION OPPORTUNITIES AHEAD HOSPITAL ONCOLOGY VACCINES Frank Clyburn PORTFOLIO Visibility into growth drivers over the next 5 years 18

  5. Slide 5: Oncology: Driving Global Leadership

    ONCOLOGY: DRIVING GLOBAL LEADERSHIP 27 Indications 15 Tumor types + MSI-H Foundational cancer Market-leading Broad-based Frank Clyburn treatment PARPi TKI >200K Patients treated Strong foundation with long runway for growth ahead 19

  6. Slide 6: KEYTRUDA: Significant Global Growth Opportunities

    KEYTRUDA: SIGNIFICANT GLOBAL GROWTH OPPORTUNITIES • Building on leadership in lung with KEYTRUDA is one of the best-selling additional reimbursement rolling out across drugs 6 years after launch Europe and other markets $10,000 $9,000 • Encouraged by early adoption in RCC and adjuvant melanoma launc

  7. Slide 7: LYNPARZA: Set for Sustained Class Leadership

    LYNPARZA: SET FOR SUSTAINED CLASS LEADERSHIP • Lynparza has class leadership in the U.S., Growth opportunities with ~60% of total PARPi prescriptions across multiple tumor types • The only PARPi with 1L maintenance indication in ovarian cancer based on strong and more ... results from SOLO-1 • POLO

  8. Slide 8: LENVIMA: Establishing as TKI of Choice

    LENVIMA: ESTABLISHING AS TKI OF CHOICE Growth opportunities • Approved in markets worldwide in RCC, across multiple tumor types HCC and differentiated thyroid cancer • Significant opportunity in China given and more … prevalence of HCC in the market • Strong commercial collaboration sets Lung cancer

  9. Slide 9: Oncology: Potential for >50 Additional Indications Over Next 5 Years

    ONCOLOGY: POTENTIAL FOR >50 ADDITIONAL INDICATIONS OVER NEXT 5 YEARS Proportion of expected indications by product Frank Clyburn Potential to nearly triple oncology indications by 2023 23

  10. Slide 10: Vaccines: Growing Global Business with Near- and Long-Term Opportunities

    VACCINES: GROWING GLOBAL BUSINESS WITH NEAR- AND LONG-TERM OPPORTUNITIES Nearly doubled vaccines • Significant long-term opportunity for revenue since 2010 pediatric and adult vaccines growth $7.3B around the world Other ZOSTAVAX • High barriers-to-entry supporting $5.7B ROTATEQ sustained, durable p

  11. Slide 11: GARDASIL: Positioned for Renewed Growth

    GARDASIL: POSITIONED FOR RENEWED GROWTH Global incidence of HPV-related cancers & diseases • Growth driven by global appeals to eliminate cervical cancer Male Common Female Oropharynx cancer • Reacceleration of growth driven by expansion into new geographies, public Recurrent Respiratory and gender-

  12. Slide 12: Hospital Portfolio: Optimized by Global Strength and Scale

    HOSPITAL PORTFOLIO: OPTIMIZED BY GLOBAL STRENGTH AND SCALE BRIDION poised for continued growth Sizable HAB/VAB pneumonia worldwide as number of surgeries that indication represents new use a reversal agent increases opportunity for ZERBAXA growth Frank Clyburn Leading portfolio of antibiotics and Re

  13. Slide 13: Innovative Portfolio and Wave of Indications Driving Global Growth

    INNOVATIVE PORTFOLIO AND WAVE OF INDICATIONS DRIVING GLOBAL GROWTH -4% Growth Contributors: KEYTRUDA GARDASIL +4% Growth Contributors: +12% Pediatric Vaccines Growth Contributors: Canada GARDASIL +9% BRIDION Lynparza KEYTRUDA +67% KEYTRUDA Lenvima JANUVIA United Lenvima Europe¹ Hospital Acute Care L

  14. Slide 14: China Becoming New Pillar of Growth

    CHINA BECOMING NEW PILLAR OF GROWTH 43% Pivoting portfolio Reaching more patients & to innovation expanding customer base 30% 25% 24% 23% Frank Clyburn 18% 18% 18% 16% 15% 14% 12% 9% Average: 11% 7% 4% 1 Merck MNC MNC MNC MNC MNC MNC MNC MNC MNC MNC MNC MNC MNC MNC 1Only includes Human Health portio

  15. Slide 15: Confident in Growth Opportunities and Ability to Execute

    CONFIDENT IN GROWTH OPPORTUNITIES AND ABILITY TO EXECUTE Frank Clyburn Innovative portfolio Significant World-class with significant international commercial teams demand-driven opportunities, executing in a growth notably in China changing environment Commercial foundation for sustained global grow

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