Phathom Pharmaceuticals, Inc. · NASDAQ:PHAT

Phathom Pharmaceuticals — Q2 2025 Earnings Presentation

14 slides from Phathom Pharmaceuticals's earnings presentation, Aug 7, 2025

  1. Slide 1: Second Quarter 2025 Earnings Conference Call

    SECOND QUARTER 2025 EARNINGS CONFERENCE CALL AUGUST 2025 NASDAQ: PHAT

  2. Slide 2: Today's Agenda

    Today’s Business Update Steven Basta, President & Chief Executive Officer Agenda Q2 2025 Financial Results Robert Breedlove, VP of Finance & Principal Accounting Officer Closing Remarks Steven Basta, President & Chief Executive Officer Question & Answer Steven Basta, President & Chief Executive Offi

  3. Slide 3: Safe harbor

    Safe harbor This presentation contains forward-looking statements. All statements other than statements of historical facts contained in this presentation, including statements regarding our plans, expectations and goals for commercialization of VOQUEZNA and potential results of our commercializatio

  4. Slide 4: Business Update

    Business Update Steven Basta, President & Chief Executive Officer 4

  5. Slide 5: Filled VOQUEZNA prescriptions are growing meaningfully

    Filled VOQUEZNA prescriptions are growing meaningfully Quarterly Filled Prescriptions1 ~36% ~173,000 580,000 + ~118,000 ~127,000 Filled Prescriptions ~69,000 Launch-to-Date as of 7/25/251 ~35,000 Previously: 390,000+ (as of 4/18/25) ~9,500 Q1 Q2 Q3 Q4 Q1 Q2 2024 2024 2024 2024 2025 2025 1 IQVIA + Bl

  6. Slide 6: Continued growth in cumulative writers; Q3 focus shifting to GI writing depth

    Continued growth in cumulative writers; Q3 focus shifting to GI writing depth Quarterly Cumulative Writers1 GI PCP2 ~24% ~28,300 29,300 + ~17,800 ~22,800 Cumulative Writers ~12,400 Launch-to-Date ~7,250 as of 7/18/251 ~2,900 Previously: 23,600+ (as of 4/11/25) Q1 Q2 Q3 Q4 Q1 Q2 2024 2024 2024 2024 2

  7. Slide 7: Q3 sales target realignment

    Q3 sales target realignment Launch-to-Date Q3 2025: Increasing Calls Volume by Specialty1 on High-Value Sales Targets ~37K HCPs 30% 2 PCP • Nearly all GIs 70% GI • All existing writers • High decile PCPs 1 IQVIA + BlinkRx as of 7/18/25 (launch-to-date data reflects IQVIA restatements). 7 2 Includes

  8. Slide 8: Rapid, potent, durable acid suppression profile

    RAPID POTENT DURABLE acid suppression profile 8

  9. Slide 9: Financial guidance for 2025

    Financial guidance for 2025 FY 2025 Q3 2025 Q4 2025 $165M to <$60M <$55M $175M net revenues non-GAAP non-GAAP operating expense1 operating expense1 9 1 Forecast excluding stock-based compensation and other non-cash items.

  10. Slide 10: Rapid, potent, durable acid suppression profile

    RAPID POTENT DURABLE acid suppression profile 10

  11. Slide 11: Q2 2025 Financial Results

    Q2 2025 Financial Results Robert Breedlove, VP of Finance & Principal Accounting Officer 11

  12. Slide 12: Key financial measures: cash, net revenues, and operating expenses

    Key financial measures: cash, net revenues, and operating expenses in cash and $149.6M cash equivalents as of June 30, 2025 We anticipate reaching profitability in 20261 Quarterly Net Revenue Quarterly Operating Expenses Non-GAAP SG&A Non-GAAP R&D Stock-based compensation $40M $39.5 $120M $103.7 $10

  13. Slide 13: Closing Remarks

    Closing Remarks Steven Basta, President & Chief Executive Officer 13

  14. Slide 14: Question & Answer

    Question & Answer Steven Basta, President & Chief Executive Officer Robert Breedlove, VP of Finance & Principal Accounting Officer 14

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