Euroapi Sa · EURONEXT:EAPI

Euroapi Sa — Investor Presentation (November 2023)

95 slides from Euroapi Sa's investor presentation, November 2023

  1. Slide 1: EUROAPI Investor Deck – November 2023

    EUROAPI Reinventing Active Ingredients solutions to sustainably meet clients and patient’s needs around the world Investor Deck – November 2023

  2. Slide 2: Content

    Content 1. Euroapi in a nutshell 2. The Active Pharmaceutical Ingredients (API) market 3. Strategy and competitive positions 4. Deep dive on API Solutions 5. Deep dive on CDMO 6. 2022 operational performance and financial KPIs 7. H1 2023 results 8. ESG Roadmap 9. Governance 10. Relationship with San

  3. Slide 3: Solid fundamentals for a value-creating sustainable growth

    1 Global presence in the growing Active Ingredient Solutions business 2 >80 billion€ total addressable market 3 Cutting-edge technologies and a leading European industrial footprint Solid fundamentals for a value-creating 4 Accelerated growth of the API Solutions business sustainable growth 5 Rapidl

  4. Slide 4: EUROAPI in a nutshell

    EUROAPI in a nutshell Reinventing Active Ingredient Solutions to sustainably meet customers’ and patients’ needs around the world

  5. Slide 5: A worldwide leader in Active Ingredient Solutions

    A worldwide leader in Active Ingredient Solutions 2 activities API €976.6M Solutions Net Sales ~3 450 CDMO in 2022 employees ~200 Commercial presence in APIs >80 countries P. 5

  6. Slide 6: 80+ Bn euros Total Addressable Market

    80+ Bn euros Total Addressable Market API market Sustained growth 2022 – in euros Small molecules – 66 Bn Merchant API market revenues, €bn 112 106 99 91 83 Merchant market 89 84 API market 83 Bn 79 160 Bn 73 66 17 18 20 22 23 2022 2023 est. 2024 est. 2025 est. 2026 est. Large molecules Small molecu

  7. Slide 7: Main activities

    Main activities API Solutions CDMO Customized development and Manufacturing and distribution of manufacture of active ingredients for the differenciated APIs pharmaceutical and biotechnology industries N°1 In small molecules N°7 Ambition : N°5 in 2025 • Unique portfolio of technologies • Approximate

  8. Slide 8: Growth strategy

    Growth strategy Strengthening the Growth and expansion of Operational API Solutions portfolio CDMO platforms Excellence Enhance product and Develop the CDMO business Improve financial performance customer portfolio and by leveraging existing through cost and working optimize product and capabilities

  9. Slide 9: Global presence and unique industrial footprint with six sites in Europe

    Global presence and unique industrial footprint with six development and manufacturing sites in Europe Haverhill Frankfurt Haverhill Spray drying Process analytical technology Elbeuf Budapest St Aubin-lès-Elbeuf Paris Microbial fermentation, Vitamin B12 HQ Brindisi Vertolaye Vertolaye API, Corticost

  10. Slide 10: Well-balanced portfolio, focused on differentiated APIs

    Well-balanced portfolio, focused on differentiated APIs 2022 Net Sales by activities 2022 Net Sales by molecules Other Clients 52% Large CDMO Molecules 10% 10% Highly Potent API Molecules Solutions 9% 35% Biochemistry- API 976.6 M€ 976.6 M€ fermentation Solutions 15% 38% Complex Chemistry 66% CDMO 1

  11. Slide 11: Ambitious ESG commitments

    Ambitious ESG commitments Offer safe products and a Accelerate innovation for Create a safe & multicultural Uphold best in class corporate resilient & responsible supply environmental sustainability workplace governance chain P. 11

  12. Slide 12: Use of cash policy consistent with the growth strategy

    Use of cash policy consistent with the growth strategy Investments to support performance and organic June 2023: €50m Capex in a new growth (Research and Development, industrial Prostaglandin production site in investments...) Budapest Growth September 2023: €10m acquisition of Biano GMP, an oligonu

  13. Slide 13: Stable shareholder base

    Stable shareholder base L'Oréal 5% Fonds French Tech Souveraineté* 12% France 33% UK Institutional 24% Investors** 44% US 22% Sanofi* Continental 30% Europe 19% ROW 2% Individual Shareholders 9% *: Two years lock-up starting 06 May 2022 P. 13 **: May 2023

  14. Slide 14: Diversified and committed Board of Directors

    Diversified and committed Board of Directors Viviane Monges Chair of the Board & Interim CEO Emmanuel Elizabeth Bastoni Cécile Rodolfo Claire Mattias Blin lead-Director Dussart Savitzky Giraut Perjos Employee representatives Independent Guillaume Géraldine Adeline Mortelier Leveau Le Franc Kevin Mar

  15. Slide 15: Partnership with Sanofi

    Partnership with Sanofi Manufacturing and Supply by Euroapi of certain Active Pharmaceutical Ingredients for Sanofi ("Global Manufacturing Agreement") Partial protection clauses for both parties, particularly in the event of significant changes in the macro-economic environment (raw material prices,

  16. Slide 16: 2022 key figures

    2022 key figures Net Sales Core EBITDA CAPEX 976.6 m€ +8.5% 120.0 m€ 138.3 m€ API Solutions 14.2% +5.3% +8.5% of Net Sales CDMO +18.3% Core EBITDA margin 45% growth CAPEX 12.3% Large molecules +79.9% P. 16

  17. Slide 17: The API merchant market: A growing 80+ billion euros Total Addressable Market

    The Active Pharmaceutical Ingredients (API) merchant market: A growing 80+ billion euros Total Addressable Market

  18. Slide 18: 80+ Bn euros total addressable market

    80+ Bn euros total addressable market Sustained growth Growth drivers (2022-2027) Merchant API market revenues, €bn Aging population, increased access to healthcare, patents Pharmaceutical +2% to +3% development, increased market generics penetration, new Volumes 119 drug development 112 106 Volume

  19. Slide 19: 350 Molecules approved by the FDA between 2016 and 2022

    350 Molecules approved by the FDA between 2016 and 2022 Other 3% mAbs* 20% Antibody-drug Conjugates (ADC) 2% Small interfering RNA 1% 2022 market size 83 bn euros Enzyme and Proteins Small Molecules 1% (chemical synthesis, biochemistry, HP-API Oligonucleotides 65% 2% Peptides 6% *: out of Euroapi’s

  20. Slide 20: API segments: Main molecules and therapies

    API segments Main molecules and therapies Small Molecules Large Molecules Oligonucleotides, Peptides & Complex Chemistry HP-APIs Biochemistry MaBs and others Lipids Molecule Size Small & Medium Variable Medium Large or mix Molecule structure Increasingly complex and technologically sophisticated Com

  21. Slide 21: API segments: Market size and estimated growth

    API segments Market Size and estimated growth 17.0% Oligonucleotides Peptides 740 1200 Cytotoxic agents 12.0% 690 2021-2027 estimated market growth Antipyretics Lipids Antihistamines 280* 130 150 7.0% Vitamin B12 Prostaglandins 235 380 Opiates 250 Sartans Hormones 330 180 Steroïds 2.0% 520 Hyperphos

  22. Slide 22: Market value chain and competitive landscape

    Market value chain and competitive landscape Marketing and Product API process API Drug Product Packaging & Discovery finished development development manufacturing manufacturing Logistics product sales API focused CDMO Integrated CMDO Pharmaceutical Companies with a CMDO P. 22

  23. Slide 23: Competitive landscape by Molecules and technologies

    Competitive landscape by Molecules and technologies Peptides / Oligos Large Only Peptides molecules Biologics Complex chemistry Fermentation Hormones Highly Potent Prostaglandins APIs Other Particle engineering & flow chemistry Only flow chemistry Only flow chemistry Only flow chemistry Sources Comp

  24. Slide 24: A long cycle and regulated industry

    A long cycle and regulated industry Illustrative API Supplier Registration Process Evaluation & Assessment Lab-scale of Finished (procurement, business data, Sampling of API batches & Dosage Formulation (FDF) quality audits) Shipment Batch Testing 1 to 4 months 1 to 3 months 1 to 3 months FDF Regist

  25. Slide 25: Strategy, and competitive advantages

    Strategy, and competitive advantages Focus on Growth and Value Creation

  26. Slide 26: Focused growth strategy and operational levers

    Focused growth strategy and operational levers Strengthening the Growth and expansion of Operational API Solutions portfolio CDMO platforms Excellence Enhance product and Develop the CDMO business Improve financial performance customer portfolio and by leveraging existing through cost and working op

  27. Slide 27: Leverage our #1 position in differentiated small molecule APIs

    Leverage our #1 position in differentiated small molecule APIs, state-of-the-art technology & innovative capabilities to expand our CDMO offering API Solutions CDMO Supply of differentiated and complex APIs with the Customised API development and flexible manufacturing Overview broadest offering in

  28. Slide 28: A global API and CDMO champion

    A global API and CDMO champion #1 small molecule API Top 5 ambition in CDMO by 2025 % share1 of total merchant API market (including CDMO) in 2019 % share1 of CDMO market in 2019 2.6% L 4.7% 1.2% eur 1.1% 0.9% n 1.0% 0.9% teva 0.8% 0.8% teva 0.7% 0.7% siegfried 0.7% 0.7% 2 a 0.6% 0.7% centre 0.6% 0.

  29. Slide 29: Leading positions in high growth – high value-added segments

    Leading positions in high growth – high value-added segments Large Molecules Complex chemistry Fermentation HP APIs Peptides Oligonucleotides Steroids Alkaloids Sartans Anti-infectives B12 & deriv1 Prostaglandins Emerging presence EUROAPI POSITIONS3 Top 52 by Top 32 #3 #1 #3 #1 #3 #1 20.0% 2025 by 2

  30. Slide 30: State-of-the-Art Technologies, with capabilities in innovative segments

    State-of-the-Art Technologies, with capabilities in innovative segments Complex Chemistry – Large Molecules Fermentation Frankfurt Ujpest Vertolaye Haverhill Elbeuf Brindisi • Solid phase chemistry for • Highly Potent product • Complex organic • High volume industrial • Large scale fermentation • La

  31. Slide 31: Launch of major Capex projects to support future sustainable growth

    Launch of major Capex projects to support future sustainable growth Jul. 22 - €24m* in a new 140,000 tons annual steam generation Payback biomass boiler in Elbeuf • Reduced exposure to energy fluctuations and availability • Reduced site’s CO2 emissions (-76%) < 3 years for projects < 7 years for str

  32. Slide 32: Acceleration of the company's transformation

    Acceleration of the company’s transformation Culture change in motion for a more agile, and customer-centric company Adapt our operating model to support best-in-class CDMO roadmap Streamline and simplify processes and tools Enhance procurement agility to better manage input costs and mitigate purch

  33. Slide 33: Deep Dive API Solutions

    CUfOAPI Deep Dive API Solutions

  34. Slide 34: API Solutions: Commercial Excellence as a driver of business growth

    API Solutions Commercial Excellence as a driver of business growth Capacity building Cross-selling Pricing enhancements Exc. Sanofi of sales from clients that buy Under c. 30% Under  54% 4+ APIs Purchase Contract contract Prostaglandins c.70% Orders  80- purchase <3 APIs 90% c.75% of the portfolio

  35. Slide 35: Strong competitive positions in complex and differentiated APIs

    API Solutions Strong competitive positions in complex and differentiated APIs 80% % of portfolio with high level of differentiation1 50% 0% 0 150 300+ # of APIs in portfolio P. 35

  36. Slide 36: More than 185 APIs serving more than 600 high-profile clients

    API Solutions More than 185 APIs serving more than 600 high-profile clients API family Ranking1 Number of APIs Number of clients Main characteristics Sole supplier on ~45% of revenues Anti-infectives #1 10 50-100 (Pristinamycine & Gamithromycin) Fermentation #3 Sole Western supplier and best-in-clas

  37. Slide 37: Almost 600 clients in 80 countries

    API Solutions Almost 600 clients in 80 countries ~372.8 M€ revenues OTHER PHARMA CONSUMER (52% of API Solutions COMPANIES HEALTHCARE Sales in 2022) GENERIC COMPANIES ~275 ~165 BIOTECH CDMO ANIMAL ~45 & RETAILERS HEALTH FOOD ~20 ~20 ~15 ~5 Nber of customers P. 37 Sources : Companies’ websites

  38. Slide 38: ~55% of sales in highly differentiated APIs

    API Solutions ~55% of sales in highly differentiated APIs Based on 2020 sales1 of EUROAPI Highly differentiated APIs Differentiation criteria •1 Niche market characteristics Complex chemistry Fermentation HP-APIs • No/limited low-cost competition 100% • Markets with less than 5 suppliers or total ma

  39. Slide 39: A comprehensive range of APIs covering more than 70 therapeutics usage (1/2)

    API Solutions A comprehensive range of APIs covering more than 70 therapeutics usage (1/2) 35 <5 20 Non-narcotic opioids & opiates – Stéroïds – Vertolaye (FR) Sartans – Budapest (HUN) Francopia (FR) Prednisolone, Methylprednisolone, Codeine phosphate, Naloxone hydrochloride, Dexamethasone, Hydrocort

  40. Slide 40: A comprehensive range of APIs covering more than 70 therapeutics usage (2/2)

    API Solutions A comprehensive range of APIs covering more than 70 therapeutics usage (2/2) 10 15 Anti-infectives Prostaglandins Brindisi (IT) Elbeuf, Vertolaye (FR) Budapest (HUN) Pristinamycin, Gamithromycin, Beraprost, Latanoprost, Rifaximin, Teicoplanin, Rifampicin Limaprost High Potent APIs Bron

  41. Slide 41: Deep Dive CDMO

    CUfOAPI Deep Dive CDMO

  42. Slide 42: CDMO: A key growth and profitability driver

    CDMO A key growth and profitability driver From the pre-clinical to the commercial phase 6 to 12 months lag between project attribution and first revenue recognized     Pre-clinical/Phase 1 Phase 2 Request For Proposal Phase 3 Commercial phase Up to 4 years Up to 3 years process Up to 3 years 8-

  43. Slide 43: CDMO: Increased traction with accelerated commercial momentum

    CDMO Increased traction with accelerated commercial momentum Requests For Proposals received 230 Others 5% 35% from big Fermentation Pharma 20% Complex Chemistry 50% Biotech 45% 15% mid size Large companies Molecules 30% 120 ROW 7% USA 23% 40 Europe 70% Average 2019-2020 2021 2022 P. 43

  44. Slide 44: CDMO: Accelerated profitable growth through portfolio rebalancing

    CDMO Accelerated profitable growth through portfolio rebalancing 6 to 12 months lag between project attribution and first revenue recognized Pre-clinical/Phase 1 Phase 2 Request For Proposal Phase 3 Commercial phase Up to 4 years Up to 3 years process Up to 3 years 8-10 years Mostly lab activities F

  45. Slide 45: CDMO: Towards an end-to-end offer for peptides and oligos

    CDMO Towards an end-to-end offer for peptides and oligos 1 2 3 4 5 Oligonucleotides Peptides Conjugation Linkers Building blocks Position EUROAPI at Participate in strong Leverage chemistry Offer innovative Complement end-to-end forefront of emerging underlying market heritage for complex linkers to

  46. Slide 46: 2022 results and Financial KPIs

    2022 results and Financial KPis

  47. Slide 47: FY 2022 key operational figures

    FY 2022 key operational figures Net Sales Core EBITDA CAPEX €976.6m €120.0m €138.3m +8.5% API Solutions 14.2% +5.3% +8.5% growth of Net Sales CDMO +18.3% Core EBITDA margin 12.3% 45% in Growth Capex Large Molecules +30% vs. 2021 +79.9% P. 47

  48. Slide 48: Increased contribution from large molecules in line with growth strategy

    Increased contribution from large molecules in line with growth strategy Per type of molecule 2022 ∆% vs 21 Key drivers Growth driven by a strong demand from Peptides and Large molecules €98.4m +79.9% oligonucleotides Highly potent Negatively impacted by the temporary suspension of €82.2m -19.0% pro

  49. Slide 49: Net Sales evolution

    Net Sales evolution 8.5% growth In Million euros and annual growth API Solutions : +5.3% High-single digit growth of sales to Other Clients driven by the execution of the commercial excellence strategy + 33.8% 976.6 Price adjustments with Other Clients fully delivered in 2022 + 10.7% Contractual cla

  50. Slide 50: Increase in Gross Profit despite energy and raw materials impacts

    Increase in Gross Profit despite energy and raw materials impacts Core EBITDA negatively impacted by the suspension of prostaglandin production in late Q4 +1.5 pts +2.1 pts +1.3 pts 14.0% 12.3% 12.3% +0.3 pts +4.6 pts -8.1 pts -1.4 pts +1.5 pts Core EBITDA 2021 Volume Price & Mix Performance Energy

  51. Slide 51: Overall Cost Structure (Cost of Goods Sold)

    Overall Cost Structure (Cost of Goods Sold)* Others (waste, maintenance,...) 23% Raw Materials 33% • Fixed costs: 55% • Variable costs: 45% Depreciation & Amortization 7% Energy Staff Costs 12% 25% P. 51 *: Rounded figures – Based on 2022 data

  52. Slide 52: Solid balance sheet and financial flexibility

    Solid balance sheet and financial flexibility € in millions 111.3 19.8 -66.5 79.9 -2.6 -25.6 Of which €(31.7)m inventories €(29.6)m trade receivables -167.4 Of which €88.7m Capital increase €21.4m payables Of which €(138.3)m Capex in line with growth capex strategy Net Cash Position Operating Cash F

  53. Slide 53: H1 2023 results

    CUfOAPI H1 2023 results

  54. Slide 54: H1 2023 key operational figures

    H1 2023 key operational figures Net Sales Core EBITDA CAPEX €496.6m €62.5m €69.3m +2.6% Of which Sanofi 14.0% €244.1m of Net Sales -1.3% Core EBITDA Of which Other Clients margin €252.5m 12.6% +6.8% 51% in Growth Capex P. 54

  55. Slide 55: Net Sales growth driven by sales to Other Clients

    Net Sales growth driven by sales to Other Clients, and impacted by the suspension of prostaglandin production over the period In Million euros and annual growth +2.6% growth API Solutions: +0.2% CDMO: +9.8% €483.8m €496.6m CDMO: €122.2m + 1.9% + 18.5% CDMO: €134.2 Other 69.8 -1.2% -1.8% 82.7 Other C

  56. Slide 56: Net sales per molecules

    Net sales per molecules Per type of molecule H1 2023 ∆% vs H122 Key drivers Large molecules €35.0m -26.9% Discontinuation of a CDMO phase 3 project with Sanofi, and phasing impact Negatively impacted by the suspension of prostaglandin Highly potent molecules €43.7m -7.3% production (cc. €(15)m on H1

  57. Slide 57: H1-2023 CAPEX – Investing in growth projects

    H1-2023 CAPEX – Investing in growth projects FY 22 FY 23 target €138.3 m €120 m to €130 m Maintenance Capex 49% 86.9 Growth 69.3 Capex 51.4 51% 2022 2023 H1 H2 P. 57

  58. Slide 58: Key initiatives to sustain future profitable growth

    Key initiatives to sustain future profitable growth €50 million capex investment dedicated to the installation of a new state-of-the-art production plant at the Budapest site that will more than double the overall prostaglandin capacity of the site by 2027 Enhanced R&D organization with the creation

  59. Slide 59: From Net Sales to Core EBITDA

    From Net Sales to Core EBITDA In € millions H1-2023 H1-2022 Net sales 496.6 483.8 Slight decrease in Gross Profit due to the impact of the suspension Gross profit 97.0 97.7 of prostaglandin production over the period, and inflation headwinds, partially offset by price increases, product mix, and Gro

  60. Slide 60: Price increases, product mix, and operational efficiencies almost compensated inflation headwinds

    Price increases, product mix, and operational efficiencies almost compensated inflation headwinds +1.6 pts  Total impact of input cost inflation in H1 23 vs. H1 22: €(37)m +4.8 pts  cc. 65% of FY 2024 energy costs hedged at the end of June 2023 +3.1 pts -1.8 pts -0.9 pts -0.5 pts -8.6 pts Rounded

  61. Slide 61: From EBITDA to Net Income and EPS

    From EBITDA to Net Income and EPS In € millions H1-2023 H1-2022 EBITDA 52.1 60.8 Depreciation and Amortization 36.1 34.7 Operating Income 16.0 26.1 Financial Result (3.3) (2.3) Income before Tax 12.6 23.8 Including €46.8m deferred tax assets derived from the Income Tax expenses 50.1 (7.0) revaluatio

  62. Slide 62: Working capital

    Working capital Inventory - Months on Hand* 8.1 7.6 December 7.3 In € millions June 2023 June 2022 2022 Working Capital 741.0 639.3 659.7 H1 2022 FY 2022 H1 2023 Of which 667.8 594.7 590.0 inventories Receivables – DSO** 79 Of which trade 70 70 238.0 264.2 266.6 receivables Of which trade (164.8) (2

  63. Slide 63: Net Debt evolution

    Net Debt evolution € in millions Of which €(69.3)m Of which Capex €(66.0)m inventories (business seasonality and input cost inflation) €30.1m trade receivables €(49.0)m payables Rounded figures €(90.6)m Core Free Cash-Flow compared by €(40.2)m in H1 2022 P. 63

  64. Slide 64: Increased number of RFPs from big pharma

    Increased number of RFPs from « big pharma » Higher average value per proposal driven by increased commercial phases Number of RFPs received by type of Customers Proposals for Commercial Phase H1 2022 H1 2023 117 106 Biotech 10% 40% 59 of proposals for of proposals for 55 commercial commercial phase

  65. Slide 65: Increasing opportunities from reshoring and repatriation linked commercial phase projects

    Increasing opportunities from reshoring and repatriation linked commercial phase projects 18 -6 79 79 -12 Phase 1 17 of which 18 • 9 projects on pre- Of which and earlier approval or in the • 2 late-stage projects with Sanofi 17 commercial phase, 14 Phase 2 driven by RSM and • 1 COVID-19 related API

  66. Slide 66: Portfolio gradually de-risked towards commercial phase projects

    Portfolio gradually de-risked towards commercial phase projects, while building the pipeline in the early-stage phases, particularly in large molecules H1 2022 H1 2023 Large H1-22 8 3 1 2 14 molecules 8 6 1 3 18 H1-23 45% 47% of projects at of projects at commercial commercial H1-22 2 2 2 6 phase ph

  67. Slide 67: FY 2023 Guidance (updated on 09-OCT-23)

    FY 2023 Guidance (updated on 09-OCT-23) The Group expects in 2023: • Net Sales are now expected to grow between +3% and +5%, compared to +7% to +8% previously, • Core EBITDA margin is now expected to be between 9% to 11%, compared to 12.5% to 13.5% previously, • CAPEX guidance remains between €120 m

  68. Slide 68: Ambitious and Integrated ESG Roadmap

    Ambitious and Integrated ESG Roadmap

  69. Slide 69: Our commitments

    Our commitments Offer safe products and a Accelerate innovation for Create a safe & Uphold best in class resilient & responsible environmental multicultural workplace corporate governance supply chain sustainability We provide high quality products We propose innovative processes We offer our employ

  70. Slide 70: Commitment One: Offer safe products and a resilient & responsible supply chain

    Commitment One Offer safe products and a resilient & responsible supply chain P. 70

  71. Slide 71: Commitment two: Accelerate innovation for environmental sustainability

    Commitment two Accelerate innovation for environmental sustainability Objectives P. 71

  72. Slide 72: Commitment three: Create a safe & multicultural workplace

    Commitment three Create a safe & multicultural workplace Objectives P. 72

  73. Slide 73: Commitment four: Uphold best-in-class corporate governance

    Commitment four Uphold best-in-class corporate governance Objectives P. 73

  74. Slide 74: 2022 achievements

    2022 achievements Accelerate innovation Create a safe and Uphold best-in-class for environmental multicultural corporate sustainability workplace governance 100% sites 30% women in a ISO14001/50001 75% leadership position by Achieved United Nations Global certification by 2023 2025 Compact commitmen

  75. Slide 75: Climate Fight: CO2 emissions

    Climate Fight C02 emissions GHG emissions by scope Scopes 1 & 2 -19.9% 30,061 61,317 5% 114,046 9% 102,953 91,378 74,043 75,582 61,317 40,003 572,868 86% 30,061 27,371 2020 2021 2022 Scope 1 Scope 2 Scope 1 Scope 2 Scope 3 p.75 * MWh

  76. Slide 76: Strongly committed to Health & Safety (H&S) and Environment

    Strongly committed to Health & Safety (H&S) and Environment ISO 14001 ISO 50001 Pharmaceutical Supply Environmental Energy management Chain Initiative (PSCI) Best practice Best practice Audits Vertolaye Since 2000 ~ By 2023 Since 2022 Elbeuf Since 2022 Since 2017 ~ By 2023 Frankfurt Since 1999 Since

  77. Slide 77: Climate Commitment ~ -30% CO2 emissions by 2030

    Climate Commitment ~ -30% CO2 emissions by 2030 (scopes 1 & 2 / vs 2020) Total energy consumption Building of a biomass heating ~ 100% renewable electricity on - 9.2% in 2 years* plant in Elbeuf sites by 2025 662754 Solar panels in Haverhill in 2023 Similar project in Vertolaye 601937 2020 2022 p.77

  78. Slide 78: Environment: Creating value for all stakeholders

    Creating value for all stakeholders Biomass heating plant in Elbeuf 24 M€ total investment IRR: 25% Finances Finances « Payback »: 5 years Up to 10.4 M€ co- investment -76% CO2 emissions vs 2020 -19kt fossil fuel use Environment Use of local natural Environment resources (wood waste - 140kt of steam

  79. Slide 79: Creating value together: Successful employees share plan

    Creating value together Successful employees share plan Global participation rate: 67.6% France: 91.5% - Germany: 69.1% 7 > 3 300 Eligible countries Eligible employees Note: 1 France, Germany, UK, Hungary, Italy, US, Japan P. 79

  80. Slide 80: Governance

    CUfOAPI Governance

  81. Slide 81: Diversified and committed Board of Directors

    Diversified and committed Board of Directors Viviane Monges Chair of the Board & Interim CEO Emmanuel Elizabeth Bastoni Cécile Rodolfo Claire Mattias Blin lead-Director Dussart Savitzky Giraut Perjos Employee representatives Independent Guillaume Géraldine Adeline Mortelier Leveau Le Franc Kevin Mar

  82. Slide 82: A diversified and engaged Board of Directors supported by three specialized committees

    A diversified and engaged Board of Directors supported by three specialized committees* 13* members Audit Committee 63% independents ESG Committee 54% women 98% attendance rate Nominations and Remunerations Committee 6 nationalities *: Data at the end of 2022 based on 13 members – The number of Dire

  83. Slide 83: Board Committees

    Board Committees 2022 2022 Meetings Attendance Rate Board 4 98% Audit Committee– 75% independents Claire Adeline Rodolfo 4 100% Giraut Le Franc Savitzky Nominations and Remunerations Committee – 66% independents Elizabeth Guillaume Emmanuel Bastoni Blin 3 100% Mortelier ESG Committee– 100% independe

  84. Slide 84: Remuneration Policy aligned with Shareholders' interest

    Remuneration Policy aligned with Shareholders’ interest

  85. Slide 85: Remuneration policy for directors

    Board of Directors Independent Directors - Remuneration Policy for 2023 60,000 euros* Board If one of the directors has attended less than 80% of the meetings, his/her fixed remuneration will be reduced accordingly Envelope annual Audit Committee / Nominations and Remunerations Committee allocation

  86. Slide 86: Remuneration policy for executive directors for 2023

    Remuneration policy for executive directors for 2023* Chair of the Board of Directors CEO Fixed Variable Target 80% (maximum 150%) Financial and 100% fixed Individual 300,000 € objectives *: As per May 2023 AGM – Please refer to October 30th Press Release for further information p.86

  87. Slide 87: Remuneration Policy of the CEO for 2023

    Remuneration Policy of the CEO for 2023 Detailed criteria* 520,000 € Fixed part Variable Target 80% (maximum 150%) *: As per May 2023 AGM – Please refer to October 30th Press Release for further information P. 87

  88. Slide 88: Relationship with Sanofi

    CUfOAPI Relationship with Sanofi

  89. Slide 89: A long-term partnership for the benefit of both companies

    A long-term partnership for the benefit of both companies 3 agreements € • Manufacturing and Supply 48.3% ̴ 1/3 of EUROAPI consolidated of the APIs purchased • Distribution revenues in 2022 by Sanofi* • CDMO * Reference in 2020 (in value) P. 89

  90. Slide 90: A strong reciprocal EUROAPI/Sanofi partnership on current and future business

    A strong reciprocal EUROAPI/Sanofi partnership on current and future business A partnership guided by different agreements Manufacturing Reverse MSA 1 and Supply 2 and Distribution 3 CDMO • Covers all API manufactured by • Reciprocal development service • Reverse MSA covers: EUROAPI and sold to Sano

  91. Slide 91: Key mechanisms designed to ensure mutually beneficial relationship

    Key mechanisms designed to ensure mutually beneficial relationship for EUROAPI and Sanofi Manufacturing and Supply Distribution Exclusivity Price-Volume Raw Material Energy costs Fixed clause Corridor Pass Through sharing prices • 42 out of the 86 APIs are • Annual compensation • Reciprocal sharing

  92. Slide 92: Financial Agenda

    Financial Agenda February 29th, 2024 (before market opening): Full Year 2023 results May 22nd, 2024: Annual Shareholder General Meeting July 31st, 2024 (before market opening): H1 2024 Results P. 92

  93. Slide 93: Contacts

    Contacts Sophie Palliez-Capian Camille Ricotier Head of Investor Relations Investor Relations Associate + 33 6 87 89 33 51 + 33 6 43 29 93 79 sophie.palliez@euroapi.com camille.ricotier@euroapi.com ir@Euroapi.com ir@Euroapi.com P. 93

  94. Slide 94: Forward looking statements

    Forward looking statements Certain information contained in this documents is forward looking and not historical data. These forward-looking statements are based on opinions, projections and current assumptions including, but not limited to, assumptions concerning the Group’s current and future stra

  95. Slide 95: Thank you!

    Thank ycou! Merci - Danke - Grazie - Készéném - Obrigada - Cnacn60 - BUBESTE WEL CUlrOAPI Active Solutions for Health

Euroapi — Investor Presentation (November 2023) on 6ix