Euroapi Sa · EURONEXT:EAPI

Euroapi Sa — Investor Day (April 2022)

102 slides from Euroapi Sa's investor day presentation, Apr 1, 2022

  1. Slide 1: EUROAPI Capital Markets Day

    EUROAPI Capital Markets Day April 1st, 2022

  2. Slide 2: Disclaimer

    Disclaimer NOT FOR RELEASE, PUBLICATION, DISTRIBUTION OR FORWARDING, IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN OR INTO ANY JURISDICTION IN WHICH THE SAME WOULD BE UNLAWFUL. BY ATTENDING THE MEETING WHERE THIS PRESENTATION IS MADE, OR BY READING THE PRESENTATION SLIDES, YOU ACKNOWLEDGE AND AGRE

  3. Slide 3: Disclaimer (Cont'd)

    Disclaimer (Cont’d) NOT FOR RELEASE, PUBLICATION, DISTRIBUTION OR FORWARDING, IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN OR INTO ANY JURISDICTION IN WHICH THE SAME WOULD BE UNLAWFUL. BY ATTENDING THE MEETING WHERE THIS PRESENTATION IS MADE, OR BY READING THE PRESENTATION SLIDES, YOU ACKNOWLEDGE

  4. Slide 4: EUROAPI Capital Markets Day: Agenda

    EUROAPI Capital Markets Day: Agenda Sanofi introduction Jean-Baptiste de Chatillon Sanofi CFO Q&A Introduction to EUROAPI, strategy and growth Karl Rotthier EUROAPI CEO Organization, culture and ESG Bruno Laforge EUROAPI Chief HR & Corporate Affairs Market overview and EUROAPI’s positioning Vincent

  5. Slide 5: Jean-Baptiste de Chatillon

    Jean-Baptiste de Chatillon Chief Financial Officer

  6. Slide 6: Play to Win: Our six-year plan – ahead of schedule

    Play to Win: Our six-year plan – ahead of schedule Today 2020-2022 2023-2025+ • Refocus with decisive actions • Transformative launches • Growth through winning assets • Agile and efficient resource deployment • Margin expansion • Leading R&D productivity 6 Investor Relations

  7. Slide 7: Transforming Sanofi to be focused and agile

    Transforming Sanofi to be focused and agile Two year process to carve-out EUROAPI February 24th, 2020 January 18th, 2021 July 2021 Sanofi announced plans to Viviane Monges joins EUROAPI CEO appointed: create EUROAPI and EUROAPI as Chair of the Karl Rotthier initiated carve-out Supervisory Board Marc

  8. Slide 8: Set up EUROAPI with optimal conditions for success

    Set up EUROAPI with optimal conditions for success Within Sanofi EUROAPI standalone • Six manufacturing sites mostly captive • Top notch CDMO infrastructure to Sanofi • Customer centric commercial strategy • Reactive commercial strategy • Dedicated management team & support functions • Limited dedic

  9. Slide 9: EUROAPI shares listing through an exceptional dividend

    EUROAPI shares listing through an exceptional dividend Advantage of a spin off Right time for EUROAPI listing Reduces execution risk given geopolitics Independence is key for EUROAPI driven market instability • attract new clients • foster culture change A firm execution date (May 6th), if approved

  10. Slide 10: EUROAPI shares distribution: Retained parity

    EUROAPI shares distribution Retained parity EUROAPI shares will be distributed1 to all Sanofi’s current shareholders as an exceptional dividend on top of 2021 cash dividend (€3.33/share) • 1 EUROAPI share for 23 Sanofi shares • ~58% of EUROAPI shares distributed 1. Subject to Extraordinary AGM appro

  11. Slide 11: EUROAPI ownership structure

    EUROAPI ownership structure ~58% of EUROAPI shares distributed to Sanofi shareholders EPIC Bpifrance Sanofi Sanofi shareholders2 12%1 ~30% ~58% EUROAPI ~50% of EUROAPI shareholders committed to a lock up period  Sanofi: 2-year lock up period  EPIC Bpifrance: 2-year lock up period  L’Oréal: 1-year

  12. Slide 12: EUROAPI: a strong strategic supplier to Sanofi

    EUROAPI: a strong strategic supplier to Sanofi  Long-term shareholder supporting EUROAPI’s growth potential  No double/differentiated voting rights  One minority shareholder Board position  Long-term MSA1 with 5 year initial term  Important customer (present and future) for EUROAPI 1. Manufactu

  13. Slide 13: EUROAPI joining the European listed CDMO peer group

    EUROAPI joining the European listed CDMO peer group 3% 34% Revenue Mix 40% 51% 2021 60% 15% 100 100 97% % % Market Cap 48.3 3.2 To be determined 7.6 2.5 (€bn) Revenue 2022e 6.0 1.2 ~1.0 0.6 0.3 (€bn) EBITDA Margin 32% 21% ≥14%1 32% 30% 2022e Small Molecules Biologics Drug Product Peptides & Oligos O

  14. Slide 14: EUROAPI deconsolidation impact for Sanofi implying loss of control

    EUROAPI deconsolidation impact for Sanofi implying loss of control 2022 BOI Industrial network Headcount margin1 6 plants ~ 3350 Slightly accretive 1. Business Operating Income margin is a non-GAAP indicator, for a definition see Form 20-F 2021 Item 5 A.1.5. 2 (p55) and Section 3.1.3.2 page 130 of S

  15. Slide 15: An additional dividend in kind through EUROAPI shares distribution

    An additional dividend in kind through EUROAPI shares distribution EUROAPI ~58% of Ordinary dividend growth Additional dividend in kind EUROAPI value Total 2021 Ordinary dividend ~€4.2bn 2001 2021 Subject to AGM’s approval on May 3rd, 2022. 15 Investor Relations

  16. Slide 16: Q&A session

    Q&A session Jean-Baptiste de Chatillon CFO 16 Investor Relations

  17. Slide 17: EUROAPI: A Global Leader in CDMO & API Solutions

    EUROAPI: A Global Leader in CDMO & API Solutions

  18. Slide 18: Introduction to EUROAPI, Strategy and Growth

    Introduction to EUROAPI, Strategy and Growth P. 18

  19. Slide 19: Introducing today's presenters

    Introducing today’s presenters 29+ 8+ 13+ 30+ 20+ 25+ 31+ 32+ Chief Human Chief Chief Executive Chief Financial Resources & Chief Operating Chief CDMO Chief Scientific Chief Strategy Commercial Officer Officer Corporate Officer Officer Officer Officer Officer Affairs Antoine Laurent Vincent Karl Rot

  20. Slide 20: EUROAPI: a global leader in CDMO and API solutions

    EUROAPI: a global leader in CDMO and API solutions Global business with premier European ~€1bn revenues by 2022 manufacturing & development footprint Global #1 in small molecule; ~25%1 CDMO today Haverhill Frankfurt ~200 APIs2 in portfolio; 55% complex & differentiated 30+ CDMO projects targeted on

  21. Slide 21: 150 year heritage and expertise now focused on standalone success

    150 year heritage and expertise now focused on standalone success Today Best-in-class Formation of Executing our Inside Sanofi   CDMO & API EUROAPI growth strategy ambition Pre-2020 2020-2021 Short-term Medium-term • Predominantly sole • Carve-out from Sanofi • Growth consistent with • Partner of

  22. Slide 22: A dynamic and nimble culture for long-term sustainable value creation

    A dynamic and nimble culture has been implemented for long-term sustainable value creation Agile and Customer-centric CDMO flexible organization approach mindset Entrepreneurial Cooperative spirit with ESG focus environment Source Company information P. 22

  23. Slide 23: #1 globally in small molecule API with differentiated technology

    #1 globally in small molecule API with differentiated technology & innovative capabilities providing base for rapidly expanding CDMO offering  2021A Sales: €902m2 API Solutions CDMO Supply of differentiated and complex APIs with the Customised API development and flexible manufacturing Overview bro

  24. Slide 24: Strategy focused on clear business and operational levers

    Strategy focused on clear business and operational levers Accelerate our CDMO Expand our differentiated Realise standalone Develop our product portfolio activities presence efficiencies • Dedicated team in place • Specialised technology • Innovative API Pipeline • Optimal efficiencies platforms thro

  25. Slide 25: EUROAPI: a unique and attractive investment opportunity

    EUROAPI: a unique and attractive investment opportunity 1 CDMO and API champion with global presence, ancient heritage and extensive expertise Attractive €70bn+ market with +6-7% p.a. growth prospects1, backed by positive secular trends and significant regulatory and 2 technical requirements State-o

  26. Slide 26: A global API and CDMO champion

    A global API and CDMO champion #1 small molecule API Top 5 ambition in CDMO by 2025 % share1 of total merchant API market (including CDMO) in 2019 % share1 of CDMO market in 2019 2.6% L 4.7% 1.2% eur 1.1% 0.9% c.€1bn Sales by end of 2022 n 1.0% (API Solutions and CDMO) 0.9% teva 0.8% 0.8% teva 0.7%

  27. Slide 27: Attractive €70bn+ market with +6-7% p.a. growth prospects

    Attractive €70bn+ market with +6-7% p.a. growth prospects Significant further growth potential in small molecule and large Large merchant API market molecules API market size (2019) Merchant API market revenues, €bn CAGR CAGR Chart Title 16A-19A 19A-24E Small +6% molecules 2019A-2021E CAGR +2% ~€59b

  28. Slide 28: EUROAPI is leading in high growth niches and differentiated segments of API

    EUROAPI is leading in high growth niches and differentiated segments of API Large molecules Complex chemistry Fermentation HP-APIs Peptides Oligos Steroids Alkaloids Sartans Anti-infectives B12 & deriv1 Prostaglandins Emerging presence EUROAPI #3 #1 #3 #1 #3 #1 positioning3 Top 52 by Top 32 by 2025

  29. Slide 29: Diversified innovation-led European footprint

    Diversified innovation-led European footprint  ~330 scientists Critical element of EU API manufacturing network spread across Haverhill 10 105 Frankfurt our 6 sites today Spray drying Peptides & Oligos Process analytical technology Small molecule APIs  45% PhDs or Process engineering engineers Flo

  30. Slide 30: Strong momentum in ongoing portfolio shift towards CDMO

    Strong momentum in ongoing portfolio shift towards CDMO Expanding development Clear focus driving the CDMO franchise pipeline Blue chip client base building • 30+ CDMO projects targeted on a rolling ~35% basis Sample CDMO partnerships • Strategic Sanofi CDMO by 2025E partnership Solid CDMO base  In

  31. Slide 31: Focused commercial strategy to drive API Solutions

    Focused commercial strategy to drive API Solutions Capacity building Cross-selling Pricing enhancements Current API Solutions:1 54% Under from clients that buy 4+ APIs contract of Sales1 c. 30% Under Vitamin B12 Prostaglandins Hormones BUT c.70% order 80-90% >10 tonnes purchase <3 APIs 25-50% 4x out

  32. Slide 32: Strategically important Sanofi relationship alongside independent strategy

    While the strategically important Sanofi relationship brings stability and revenue visibility to EUROAPI, we are rolling out our strategy as a fully independent company Four key principles drive our ongoing relationship with Sanofi Arm's length EUROAPI as Sanofi Mutually beneficial aligned on distri

  33. Slide 33: Clear objective to financial performance

    Clear objective to financial performance In line with Growth: Above market Below market market 902 Sales (€m) CDMO contribution to total sales to increase from ~25% in 2021A to ~35% in 2025E 1 2021A 2 CDMO Other clients Sanofi 2025E API Solutions >20% Core EBITDA 12.3% Margin 2021A 2 Topline growth

  34. Slide 34: Introducing the EUROAPI Management Team

    Introducing the EUROAPI Management Team Employee culture of excellence c.3,350 Global headcount 10 Countries of employee presence c.15 Years of seniority on average Highly experienced executive team Karl Rotthier Antoine Delcour Vincent Touraille Eric Berger 29 8 32 30 Chief Executive Officer Chief

  35. Slide 35: Introducing the EUROAPI Board of Directors

    Introducing the EUROAPI Board of Directors Governance standards in line with best industry practices Board of Directors Viviane Monges Chair • Board to consist of 13 members (7 independent) Karl Rotthier Adeline Le Franc EUROAPI Sanofi • Highly qualified Chair (independent): Viviane Monges Jean-Chri

  36. Slide 36: Organization, Culture and ESG

    Organization, Culture and ESG P. 36

  37. Slide 37: Our culture will enable career growth opportunities and talent management

    Our culture will enable career growth opportunities and talent management Creation of a new innovative Shift to EUROAPI corporate values and A talent management roadmap to align culture API company related behaviors with business strategy To be more agile, flexible, not a heavy process-driven • Tale

  38. Slide 38: Short term and long term incentives aligned with strategy and growth

    Short term and long term incentives aligned with the strategy and growth Short term incentives Long term incentives (LTI) at the time of listing • Make sure our employees are fully involved and committed to the future of our company • A robust bonus scheme to support the strategy and takes into cons

  39. Slide 39: Market-leading ESG strategy focusing on four core priorities

    EUROAPI has a market-leading ESG strategy focusing on four core priorities contributing to the United Nations Sustainable Development Goals A robust strategy designed inclusive of all stakeholders Medical needs Producing high-quality active ingredients that address a broad range of medical needs Sup

  40. Slide 40: Ambitious Environmental targets

    Ambitious Environmental targets, in line with EUROAPI’s position as a market- leader Current status Current targets Environment at core of EUROAPI DNA at site level, all sites being or in the path to be certified ISO50001 2023 • ~ 100% sites certified ISO50001 Frankfurt  Since 2012 Ujpest  Since 2

  41. Slide 41: Social and Governance matters are a core priority within ESG framework

    Social and Governance matters are a core priority within EUROAPI’s ESG framework Current status Current targets Health & Safety at core of EUROAPI DNA at site level, all sites being or in the path to be certified ISO14001 • ~100% sites certified ISO14001 By • Variable pay linked to sustainability /

  42. Slide 42: Market Overview and EUROAPI's Positioning

    Market Overview and EUROAPI’s Positioning P. 42

  43. Slide 43: Attractive €70bn+ market with +6-7% p.a. growth prospects

    Attractive €70bn+ market with +6-7% p.a. growth prospects Large merchant API market Significant further growth potential in small molecule and CDMO API market size (2019) Chart Title Merchant API market revenues, €bn Small 2019A-2021E CAGR +6% 99 CAGR CAGR +2% due to COVID molecules 16-19A 19-24E ~€

  44. Slide 44: Small molecules continue to drive innovation, increasingly sourced from Biotechs

    Small molecules continue to drive innovation, increasingly sourced from Biotechs EUROAPI capable of producing >80% of new drugs More than 65% of approved drugs are small molecules over the past decade EUROAPI capable of producing >80% of new drugs approved, but ADC and mABS Number of drug approvals1

  45. Slide 45: EUROAPI positioned for long-term client relationships in complex API markets

    EUROAPI positioned for long-term client relationships in complex API markets Capital and knowledge investments... …supported by favorable market trends Highly specialized Long-term and sticky technological expertise customer relationships Increasing demand for premium and technical know-how APIs Inc

  46. Slide 46: Market landscape and value chain overview

    Market landscape and value chain overview Pharma value chain and key API players1 EUROAPI focus Drug substance / Marketing Product API process Drug substance / Drug product (FDF) Packaging and Discovery and finished development development and API manufacturing manufacturing logistics product sales

  47. Slide 47: EUROAPI is the global #1 small molecule API supplier

    EUROAPI is the global #1 small molecule API supplier in a highly fragmented market Leading global API player in a highly fragmented market Top Tier API manufacturers, % share of merchant API market (2019) 2.6% Biologics 1.2% 0.9% 0.9% 0.8% 0.7% 0.7% 0.7% 0.7% 0.6% 0.6% 0.6% 0.5% 0.4% Small <0.3% mol

  48. Slide 48: EUROAPI has ambitions to be a top-5 CDMO player by 2025

    EUROAPI has ambitions to be a top-5 CDMO player by 2025 Top 15 small molecule API suppliers' CDMO API market share and revenue split Excluding players not present in small molecules Top 5 ambition by 2025 CDMO small molecules & Pep/Oligo sales (€m) ~4.7% #7 Catalog sales (€m) CDMO biologics only sal

  49. Slide 49: Break

    CUfOAPI Break

  50. Slide 50: Technology, R&D and Manufacturing Capabilities

    Technology, R&D and Manufacturing Capabilities P. 50

  51. Slide 51: EUROAPI capabilities cover c.80% of FDA approved molecules

    EUROAPI capabilities cover c.80% of FDA approved molecules Small molecules and innovative products continue to dominate the list of EUROAPI presence across API categories approved drugs FDA approved drugs between 2016 and 2021 Peptides Ch a r t T it le Small molecules 12 177 O ligos 6 Enzymes & Prot

  52. Slide 52: Multiple levers available to drive innovation

    Multiple levers available to drive innovation Molecule / Highly potent API Technology Complex chemistry Fermentation Peptides and oligos mRNA Prostaglandins Linkers / Payload • Advances in science and • New approaches to lower • Limited innovation • Capacity and • State-of-the-art technology • Deliv

  53. Slide 53: Innovation is a core value for EUROAPI

    Innovation is a core value for EUROAPI Well-connected and focused R&D organization Haverhill 10 105 Frankfurt Large & experienced  ~330 scientists spread across our 6 sites today Peptides & Oligos R&D team Spray drying  Scheduled to almost double capacity by 2025 Process analytical technology Smal

  54. Slide 54: EUROAPI possesses critical and integrated scale in a fragmented market

    EUROAPI possesses critical and integrated scale in a fragmented market EUROAPI is the largest Small Molecules API manufacturer globally... … with bigger sites Relative sales vs. EUROAPI of key small molecule players1 EUROAPI sites are 2.5 times2 bigger than 100% Western peers' 76% 75% Frankfurt site

  55. Slide 55: In-house capabilities in key technologies along with R&D centers at each site

    In-house capabilities in key technologies along with R&D centers at each site already in place to deliver full company strategy Chemistry Fermentation Frankfurt Ujpest Vertolaye Haverhill Elbeuf Brindisi • Solid phase chemistry • Highly potent product • Complex organic • High volume • Large scale •

  56. Slide 56: Manufacturing network is well-invested with capacity development projects

    Manufacturing network is well-invested, comprising a comprehensive suite of technologies with further capacity development projects underway to support medium-term growth plan EUROAPI's capacity utilization is at sustainable Additional development projects for key API families are already underway l

  57. Slide 57: All manufacturing sites are FDA & EMA inspected with strong results

    All manufacturing sites are FDA & EMA inspected with strong results including no critical finding following regulatory audits Last FDA inspection Last EMA1,2 inspection Client audits % success in audits Date # of critical findings Date # of critical findings Success rate (2018-2021)3 consistent No w

  58. Slide 58: CDMO

    CUfOAPI CDMO

  59. Slide 59: Already one of the broadest portfolios in CDMO globally

    Already one of the broadest portfolios in CDMO globally Peptides / Oligos Large Only Peptides molecules Biologics Complex chemistry Fermentation Hormones Highly potent Prostaglandins APIs 1 Other Particle engineering & flow chemistry Only flow chemistry Only flow chemistry Only flow chemistry Source

  60. Slide 60: Our CDMO strategy as a standalone entity

    Our CDMO strategy as a standalone entity is to make our best-in-class capabilities available to the entire pharma/biotech ecosystem for the first time One of the best CDMO f • Ambition to be a top-5 CDMO player by 2025 • Gradual portfolio shift towards CDMO to drive growth momentum • Best-in-class i

  61. Slide 61: Deep breadth of technologies across the full R&D spectrum powering CDMO offering

    Deep breadth of technologies across the full R&D spectrum powering CDMO offering Biochemistry molecules Large molecules Complex chemistry Highly potent (HP-APIs) Solid state derived from fermentation Complex chemical synthesis Anti-infectives and Prostaglandins, cytotoxic Peptides & oligonucleotides

  62. Slide 62: Focused efforts have triggered a meaningful rise in activity

    Focused efforts have triggered a meaningful rise in activity… Sharply increasing number of commercial Significant ramp up in RFP response rate in Substantially more RfPs received in 2021 meetings 2021 vs. prior years 2021 Number of commercial meetings Meetings covering Number of RFPs received Number

  63. Slide 63: Strong momentum evidenced by accelerating volume of RFPs

    …with strong momentum evidenced by accelerating volume of RFPs from Big Pharma and leading Biotechs worldwide January to June 2021 July to December 2021 Full Year Total RFPs received Total RFPs received • 45% Complex Chemistry 45 75 120 • • 20% Oligos & Peptides 25% Fermentation • 10% Other1 RFPs fr

  64. Slide 64: Focused CDMO efforts already yielding meaningful successes

    Focused CDMO efforts already yielding meaningful successes Portfolio and momentum building New CDMO projects won across all technologies CDMO contracts Peptides & oligos 3 3 2 22 (mostly in commercial phase) Legacy projects Fermentation 1 1 retained from before carve out Highly potent APIs 1 1 New C

  65. Slide 65: Our accelerating CDMO momentum: selected case studies

    Our accelerating CDMO momentum: selected case studies Case Study 1: Long-term life-cycle encompassing relationship Case Study 2: Rapidly expanding oligos clientele 1 2 US biopharma reliant fully Initially envisaged only >30% >60% Origination on CDMOs process transfer 2010 Oligos Are GalNAC are conju

  66. Slide 66: Our accelerating CDMO momentum: selected case studies (cont'd)

    Our accelerating CDMO momentum: selected case studies (cont’d) Case Study 5: Agreement with Sanofi for mRNA Case Study 3: State-of-the-art micronization Case Study 4: Increasing recognition of ADC development further evidences EUROAPI’s capabilities capabilities capabilities in lipids • Mandated on

  67. Slide 67: Positioned to capitalize on oligonucleotides & peptides opportunity

    EUROAPI is strongly positioned to capitalize on the broad market opportunity for oligonucleotides & peptides Selected highlights EUROAPI differentiation  One of first players in peptides (1976) with start of solid phase synthesis activities in 2004 Strong track record and  Oligonucleotide synthesi

  68. Slide 68: Strategic ambition is to develop into a one-stop-shop for peptides and oligos

    Strategic ambition is to develop into a one-stop-shop for peptides and oligos 1 2 3 4 5 Oligonucleotides Peptides Conjugation Linkers Building blocks Position EUROAPI at Participate in strong Leverage chemistry Offer innovative Complement one-stop- forefront of emerging underlying market heritage fo

  69. Slide 69: API Solutions

    CUfOAPI API Solutions

  70. Slide 70: EUROAPI's API Solutions ranks favorably in complex and niche products

    EUROAPI’s API Solutions ranks favorably in complex and niche products Illustrative segmentation of key players 80% % of portfolio with high level of differentiation1 Differentiation increasing over time 50% 0% 0 150 # of APIs in portfolio 300+ Sources Company information and estimation based on thir

  71. Slide 71: API Solutions focused on a few API families serving large clients

    API Solutions business is focused on a few API families serving large high-profile clients API family Ranking1 Number of APIs Number of clients Main specificity / complexity Sole supplier on ~45% of revenues Anti-infectives #1 10 50-100 (Pristinamycine & Gamithromycin) Fermentation #3 Sole Western s

  72. Slide 72: Majority of portfolio positioned in differentiated product segments

    Majority of EUROAPI’s portfolio positioned in differentiated product segments 2020 sales of EUROAPI ~€990M (preliminary - lastEUROAPI financials to portfolio be received)segmentation Differentiation criteria Based on 2020 sales1 of EUROAPI •1 Niche market characteristics Complex chemistry Fermentati

  73. Slide 73: Working on multiple levers to drive API Solutions growth

    Working on multiple levers to drive API Solutions growth Impact on 2025 outlook Building additional capacity for Vitamin B12, Prostaglandins & +++  Capacity building Hormones to address growing demand  Increasing scope with existing clients, benefiting from loyal Cross-selling relationships and lo

  74. Slide 74: Customers

    CUfOAPI Customers

  75. Slide 75: >500 clients well spread across the pharmaceutical landscape

    >500 clients well spread across the entire pharmaceutical landscape Breakdown of clients % of 2020 total EUROAPI Sales1 Client segment # of clients Big/specialty pharma ~275 51% Generics ~45 Biotechs ~20 15% Animal health ~15 7% 14% Distributors ~15 3% 10% Consumer health, nutrition & others2 ~165 E

  76. Slide 76: A highly diversified customer base

    A highly diversified customer base Excluding Sanofi, top 10 clients account for 21% of EUROAPI sales API Pareto: 80% of EUROAPI sales covered by 87 clients (excl. Sanofi) % of 2021 total EUROAPI Sales¹ % of 2021 total EUROAPI Sales¹ Chart Title 530 100% Top 10 Clients 24% 80% 75% Others 76% 50% 25%

  77. Slide 77: High loyalty with c.75% of clients currently monosourced

    High loyalty towards EUROAPI with c.75% of clients currently monosourced¹ Duration of client relationship Client churn per annum API sales1 per client nature Chart Title # and share of Top 20 clients per duration of relationship Client churn between 2016 & 2020 per annum 2020 sales breakdown by sour

  78. Slide 78: A strong reciprocal EUROAPI/Sanofi partnership

    A strong reciprocal EUROAPI/Sanofi partnership on current and future business For Sanofi, EUROAPI is… …a trusted API …a trusted …a trusted API 1 manufacturer MSA 2 API CDMO Devlpt 3 distributor/client • Covers all API manufactured by • Reciprocal development service EUROAPI and sold to Sanofi agreem

  79. Slide 79: Break

    CUfOAPI Break

  80. Slide 80: Financial Performance

    CUfOAPI Financial Performance

  81. Slide 81: Financial framework to deliver strong shareholder returns

    Financial framework to deliver strong shareholder returns • Topline growth driven by expansion of one of the best CDMO offering Sales growth • Commercial excellence and API Solutions portfolio shift towards niche and complex API • Procurement optimisation and cost savings plans as well as operationa

  82. Slide 82: Attractive financial profile with Core EBITDA margin expanding

    Attractive financial profile with revenue CAGR of 1% despite Covid impact; Core EBITDA margin successfully expanding with significant future upside Attractive revenue Restated Net Sales (€m) Restated Core EBITDA (€m) evolution through shift to CDMO and other clients 955 120 20.0% 902 111 892 108 EBI

  83. Slide 83: Sales primed for future performance as standalone franchise

    Sales primed for future performance as standalone franchise Restated Net Sales breakdown by business Restated Net Sales breakdown by clients CAGR CAGR YoY Growth YoY Growth 2019-2021A 2019-2021A CDMO growth +35% +7% +20% Sanofi growth +8% (12%) (2%) API Solutions growth +1% (9%) (4%) Other clients g

  84. Slide 84: Transformation of the portfolio is starting to materialize into financials

    Transformation of the portfolio is starting to materialize into financials Restated Net Sales Technology Future Growth Potential1 Growth levers 2019A 2020A 2021A 2019-21A CAGR Mostly oligos and peptides historically Large molecules €12m €22m €24m +38%  dedicated to Sanofi needs Investments planne

  85. Slide 85: EUROAPI is well positioned on high margin products

    EUROAPI is well positioned on high margin products API Solutions CDMO Peptides/Oligos: () Niche/differentiated molecules: () Indicative profitability High-potency/ ADC linkers/ lipids:  Less-differentiated molecules: () Other molecules:   Attractive levels of profitability are seen i

  86. Slide 86: Margins expanding due to business mix and industrial performance

    Margins expanding naturally due to business mix with industrial performance fuelling further upside Restated Core EBITDA (€m) Significant near-term value creation as a primary carve-out 2019A-21A CAGR +18% YoY Growth +35% +3% 120 20.0% 111 108 Increasing business mix towards high margin CDMO 18.0% 1

  87. Slide 87: We are now investing in the future growth of the company

    We are now investing in the future growth of the company Core EBITDA to benefit from the increased share of CDMO within the Cash Capital expenditure breakdown Capex plans portfolio Cash Capex evolution 2019A-2021A (€m) • Key capex projects for the medium term have already been identified: EUROAPI To

  88. Slide 88: 2022 Targets

    2022 Targets • Overall: c. €1.0bn Revenue • CDMO: 25-30% of total Sales growth • Sanofi Sales: reduced dependency Core EBITDA • ≥14% Margin (%) Capex • c.12% of sales Dividend • No dividend paid or accrued policy Leverage • Debt-free at listing policy Current geopolitical situation not expected to i

  89. Slide 89: Clear objective to delivering sizeable topline growth

    Clear objective to delivering sizeable topline growth Based on organic growth with no contribution from external opportunities or repatriation benefits CDMO c.35% Sanofi c.30-35% +6-7% CAGR CDMO 25% Sanofi 49% API Solutions – Other API Solutions - Sanofi Clients CDMO • Growth below market 9021 • Por

  90. Slide 90: Topline acceleration, mix effect and industrial performance to drive Core EBITDA

    Expected topline acceleration, mix effect and industrial performance to drive Core EBITDA increase Based on organic growth with no contribution from external opportunities or repatriation benefits >20% Operational performance 12.3%1 Mix effect • Overall cost improvement thanks to procurement 1111 To

  91. Slide 91: Clearly defined capital allocation framework

    Clearly defined capital allocation framework Key Priorities Returns to Investment shareholders Invest in organic growth drivers Organic Dividends growth 2025E Invest in capex to support growth plan Core FCF conversion2: 50-53% Disciplined M&A Mergers & Capex Acquisitions Return to shareholders1 • Su

  92. Slide 92: Closing Remarks

    CUfOAPI Closing Remarks

  93. Slide 93: EUROAPI's profitable growth is built on strong pillars

    EUROAPI’s profitable growth is built on strong pillars Well positioned to  Continued focus on innovation and CDMO deliver the future of 3 complex API  Premier consolidation platform in a highly fragmented market New growth opportunities / Inorganic growth  Financial flexibility (debt-free at list

  94. Slide 94: Q&A Session

    CUfOAPI Q&A Session

  95. Slide 95: Appendices

    CUfOAPI Appendices

  96. Slide 96: How financials have been built and restated

    How financials have been built and restated to reflect EUROAPI performance? Restatements Consolidated financial statements Deal terms3 (MSAs, Reverse MSAs, Distribution Reflect EUROAPI performance – “AS IS”, i.e., with existing conditions agreements, etc.): new pricing between Sanofi and within Sano

  97. Slide 97: Methodology for Restated APM

    Methodology for Restated APM Nature of restatement Summary MSA deal terms 1 • Reflection of the contractual terms on APIs sold to Sanofi (effective as of October 1st, 2021) using actual volumes sold (Sales to Sanofi) Distribution • Reflection of the contractual terms on APIs manufactured by Sanofi a

  98. Slide 98: Bridge from consolidated to restated APM net sales

    Bridge from consolidated to restated APM net sales Net sales restatements Bridge items FY19 Net sales bridge (€m) +27 1• MSA deal terms - (26) (25) (0) 916 892 2• Distribution Agreement Net sales 1 2 Restated FY19 consolidated 3 5 6 7 net sales FY19 4 3• UK secondary packaging FY20 Net sales bridge

  99. Slide 99: Bridge from consolidated to restated APM core EBITDA

    Bridge from consolidated to restated APM core EBITDA Core EBITDA restatements Bridge items FY19 Core EBITDA bridge (€m) +48 9.0% 1• MSA deal terms 6.3% 7.8% +14 (6) (23) (11) - - (0) 58 72 80 1 2 2• Distribution Agreement EBITDA FY19 Core Core Restated Core 3 5 6 7 consolidated adj. EBITDA FY19 4 EB

  100. Slide 100: Bridge from consolidated to restated APM Core Free Cash Flow

    Bridge from consolidated to restated APM Core Free Cash Flow Core Free Cash Flow restatements Bridge items FY20 Core Free Cash Flow bridge (€m) 1• MSA deal terms +47 (2) 24.8% 2• Distribution Agreement (16) (7) - - 10.2% (3) 27 3• UK secondary packaging 7 Core FCF FY20 1 2 Restated 3 5 6 7 8 consoli

  101. Slide 101: Comfortable liquidity cushion to support medium-term growth strategy

    Comfortable liquidity cushion to support medium-term growth strategy EUR Revolving Credit Facility Ample flexibility under new credit facility agreement Amount €451,000,000 • EUROAPI has secured a €451m 5-year Revolving Credit Facility from a pool of 7 international relationship banks Ranking Senior

  102. Slide 102: EPIC Bpifrance investment in EUROAPI

    EPIC Bpifrance investment in EUROAPI French Tech Souveraineté Convention at a glance About its investment in EUROAPI Launched in June 2020 by the French government Up to €150m investment for 12% of share capital of EUROAPI Investment envelope managed by EPIC Bpifrance Acquisition price to be determi

Euroapi — Investor Day (April 2022) on 6ix