Qtrex Quantum Ltd. · NASDAQ:QTEX
Qtrex Quantum — Inspira Technologies Oxy B.H.N. — Investor Presentation (June 2023)
36 slides from Qtrex Quantum's investor presentation, June 2023
Slide 1: Revolutionizing Acute Respiratory Care
EMPOWERED BREATHING WITHOUT LUNGS™ REVOLUTIONIZING ACUTE RESPIRATORY CARE Corporate Presentation | June 2023 Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 1
Slide 2: Forward Looking-Statements
FORWARD LOOKING-STATEMENTS This presentation of InspiraTM Technologies Oxy B.H.N. Ltd. (“Inspira Technologies” or the “Company”) contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act and other securities law. Words such as “expects,” “intends,” “pla
Slide 3: Disclaimers
DISCLAIMERS The INSPIRATM ART and the ART presented in this presentation are both referring to the sample size. There is no guarantee as to the success of any trial. In addition, there is inherent INSPIRATM ART products (as a platform). INSPIRATM ART500 was previously known as the risk and variabili
Slide 4: Inspira End-to-End Solutions
INSPIRA™ END-TO-END SOLUTIONS ACUTE LIFE SUPPORT RESPIRATORY Providing cardiac SUPPORT and pulmonary Preventing the support need for Mechanical Ventilation Expanding The Extracorporeal Blood Circulation Market to $20B* * based on Company estimates Extracorporeal Blood Circulation - A procedure in wh
Slide 5: Inspira ART HUB
INSPIRA™ ART HUB Augmented Respiration Technology HYLA™ Blood Sensor & Supporting Technologies INSPIRA™ AI Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 5
Slide 6: Market Size
MARKET SIZE $19.5B INSPIRA™ ART HUB $19.2B Acute respiratory distress Mechanical Ventilators syndrome devices by 2029¹ at a CAGR of 7.3% Driven by increasing prevalence of $20B Company Estimate by 20302 at a CAGR of 14.01% Mechanical ventilation increases risk acute lung injury and growing of infect
Slide 7: H2-2023 Planned News Alerts
H2-2023 PLANNED NEWS ALERTS On track to submit the INSPIRATM ART100 INSPIRATM ART500 expected to receive medical device to the U.S. FDA under the additional patent grant by the U.S. 510(k) pathway Patent and Trademark Office (USPTO) New INSPIRATM ART100 device to be revealed at the world’s largest E
Slide 8: Augmented Respiration Technology
INSPIRA™ CORE TECHNOLOGIES AUGMENTED RESPIRATION TECHNOLOGY Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 8
Slide 9: Extracorporeal blood circulation boosts oxygen saturation
Specifically designed extracorporeal blood circulation boosts oxygen saturation levels in minutes. Patient treated while awake NEW TREATMENT CATEGORY Extracorporeal Blood Circulation - A procedure in which the patient’s blood is circulated outside the body for oxygen enrichment and carbon dioxide re
Slide 10: Click to watch video
Click to watch video Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 10
Slide 11: Inspira AI Breakthrough
Augmented Respiration INSPIRA™ AI BREAKTHROUGH Technology Designed to continuously learn the patient and devices in real-time TARGETING Decision-supportive data HYPER- Aims to provide physicians with PERSONALIZATION monitoring and predictive analytics CARE Targeted to identify and monitor health iss
Slide 12: Shortage of Real-Time Patient Treatment
SHORTAGE OF REAL-TIME PATIENT TREATMENT Impacts quality of patient diagnosis and level of care Delays in providing patient care Time spent per patient declined significantly Lack of patient indicators & data Shortage of supportive treatment data Shortage of insight-rich data Can mean a significant M
Slide 13: Inspira AI Personalizing Treatment
INSPIRA™ AI PERSONALIZING TREATMENT DATA COLLECTION ADAPTIVE ANALYTICS Collects data and generates simulations Patient & Data Sources & augmented data models Health Indicators, EMR, Patient Personal Data Analyzes and identifies patterns, HYLA™ anomalies, trends to generate insights Blood Sensor & Su
Slide 14: Projected Milestone Timeline
PROJECTED MILESTONE TIMELINE Targeting additional strategic & distribution agreements PRODUCT H1-2023 H2-2023 H1-2024 H2-2024 2025 Cannula Patent INSPIRA™ ART FiH Pilot Clinical Study Approval Patent Approvals INSPIRA™ (First in Human) may be outside of U.S.A Clinical Study may Or FDA IDE ART500 be
Slide 15: Three Patent Families
INSPIRA™ PATENT PORTFOLIO FAMILY #1 FAMILY #2 FAMILY #3 THREE INS-001 A Cannula INS-002 Dual Lumen INS-003 PATENT Fixation Device Cannula and Methods of Use Extracorporeal Oxygenation System for Low Flow Rates FAMILIES Granted in Israel November 2022, Filed in U.S. September 2022 Granted January 202
Slide 16: Management Team
MANAGEMENT TEAM Prof. Benad Goldwasser, MD, MBA Dagi Ben-Noon, BSc Joe Hayon, MBA Avi Shabtay Executive Chairman Co-Founder, Director & CEO Co-Founder, Director & President COO Urologic surgeon, inventor & entrepreneur. Co-founded Nano Dimension M&A experience & track record Elscint Technologies New
Slide 17: Chairman of the Board
CHAIRMAN OF THE BOARD Prof. Benad Goldwasser MD, MBA Urologic surgeon, inventor, entrepreneur & venture capital VC Vast experience in leading high growth, publicly traded medical companies. Co-founded Vidamed Inc., acquired by Medtronic Inc. (NYSE: MDT). Co-founded Medinol, partnered with Boston Sci
Slide 18: First Quarter 2023 Financial Results
FIRST QUARTER 2023 FINANCIAL RESULTS $11.5M in cash, cash equivalents and COMPANY WELL FINANCED FOR INSPIRA™ ART100 On-going HYLA™ deposits as of March 31, 2023 FDA Clearance Research Clinical Study Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 18
Slide 19: Appendices
APPENDICES Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 19
Slide 20: The Respiratory Gap
THE RESPIRATORY GAP SUPPLEMENTAL MECHANICAL VENTILATION Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 20
Slide 21: 20M Patients Each Year on Mechanical Ventilation
20M PATIENTS EACH YEAR ON MECHANICAL VENTILATION* * Forum of International Respiratory Societies. The Global Impact of Respiratory Disease – Second Edition. Sheffield, European Respiratory Society, 2017 Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 21
Slide 22: Mechanical Ventilation – The Current Standard
MECHANICAL VENTILATION – THE CURRENT STANDARD • Intubation & coma • No real-time patient data monitoring • High risks of bacterial infections A SLIDING • High risks of pulmonary edema & lung damage 50% • High risk of collapsed lung • Risk of vocal cord paralysis • Heart & blood flow changes (less ox
Slide 23: Inspira ART100 Overview
INSPIRA™ ART100 OVERVIEW LIFE SUPPORT An extracorporeal blood circulation device designed to provide cardiac and pulmonary support Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 23
Slide 24: About Inspira ART100
WHAT IS THE INSPIRA™ ART100? An extracorporeal blood circulation device designed to provide cardiac and pulmonary support. ABOUT HOW DOES IT WORK? INSPIRA™ In order to replace the entire heart-lung function, the INSPIRA™ ART100 circulates the entire output of a patient's blood (5-7 liters per minute
Slide 25: Inspira ART100 Key Features
USER FOCUS • Intuitive user-centric software and display NEXT GENERATION - INSPIRA™ • Ergonomic device configuration • Troubleshooting KEY FEATURES ART100 • Compatible with Inspira’s HYLA™ blood sensor intended to provide continuous blood parameter COMPETITIVE PATIENT FOCUS measurements in real-time
Slide 26: HYLA Blood Sensor Overview
HYLA™ BLOOD SENSOR OVERVIEW BLOOD DETECTION & MEASUREMENT A non-invasive optical blood sensor to measure blood parameters continuously and in real-time during extracorporeal blood circulation procedures Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 26
Slide 27: About HYLA Blood Sensor
WHAT IS THE HYLA™ BLOOD SENSOR? A non-invasive optical blood sensor being developed using INSPIRA™ AI to measure blood parameters, intended to provide continuous blood parameter measurements in real-time during extracorporeal ABOUT procedures. HOW DOES IT WORK? HYLA™ The optical blood sensor takes c
Slide 28: HYLA Blood Sensor Key Features
USER FOCUS • Easy clip-on sensor mounted onto the blood tube HYLA™ • INSPIRA™ AI provides continuous information of key blood parameter in real time NEXT GENERATION - BLOOD • INSPIRA™ AI alerts of trending changes in the patient’s condition to allow early medical intervention KEY FEATURES SENSOR • I
Slide 29: Inspira Pathway to Market
INSPIRA™ PATHWAY TO MARKET Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 29
Slide 30: Total Addressable Market
TOTAL ADDRESSABLE MARKET INSPIRA™ INSPIRA™ HYLA™ & Supporting ART500 ART100 Technologies ~$18B Company Estimate ~$0.9B by 2030¹ at a CAGR of 5.75% ~$1.1B Company Estimate 1. https://www.verifiedmarketresearch.com/product/extracorporeal-membrane-oxygenation-machine-market/ Copyright © 2018-2023 Inspi
Slide 31: Inspira Market Opportunity
INSPIRA™ MARKET OPPORTUNITY TAM $20B North America SAM $6.4B ~$1.3B Europe ~$1B SOM $3.2B Asia Pacific South America ~$600M SOM Company Estimates ~$150M Primary markets: North America & Europe Rest of World ~$150M TAM- Total addressable market SAM- Serviceable Available Market SOM- Serviceable Obtai
Slide 32: Inspira Reimbursement Strategy
INSPIRA™ REIMBURSEMENT STRATEGY Inspira plans to utilize existing CPT Codes Expected to eliminate complications associated with MV Aimed to reduce length of stay & re-admissions Designed to reduced costs & operational expenses Designed to reduce Source :cms.gov - MS DRG based reimbursement for respi
Slide 33: Strong Board of Directors
STRONG BOARD OF DIRECTORS Prof. Benad Goldwasser, MD, MBA Tal Parnes Lior Amit Limor Rozen Chairman of the Board of Directors Director Director Director Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 33
Slide 34: Scientific Advisory Board
SCIENTIFIC ADVISORY BOARD World-Renowned Key Opinion Leaders Prof. Daniel Brodie Prof. Eddy Fan Dr. Stephan Ledot Intensivist & ECMO Advisor Intensivist & ECMO Advisor Intensivist & ECMO Advisor President-elect of the Extracorporeal Medical director of the extracorporeal World-renowned expert in cri
Slide 35: Scientific Advisory Board
SCIENTIFIC ADVISORY BOARD World-Renowned Opinion Leaders Key Prof. Eli Gabbay Dr. Avraham Abutbul Dr. Orit Cohen Jacob Dr. Sharon Marx Respiratory Disease Specialist Intensivist Veterinary Surgeon Physical Organic Chemistry Professor of Respiratory Medicine, Senior physician at Hadassah Specialist i
Slide 36: Thank You!
THANK YOU! EMPOWERED BREATHING WITHOUT LUNGS™ Copyright © 2018-2023 Inspira Technologies OXY B.H.N. LTD., All rights reserved 36
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