Senseonics Holdings, Inc. · NASDAQ:SENS

Senseonics — Investor Presentation (May 2025)

22 slides from Senseonics's investor presentation, May 2025

  1. Slide 1: Eversense CGM System Corporate Overview

    Eversense ® CGM System THE WORLD’S FIRST AND ONLY LONG-TERM CONTINUOUS GLUCOSE MONITORING SYSTEM Corporate Overview May 20251

  2. Slide 2: Forward-looking Statements

    Forward-looking Statements Any statements in this presentation about future expectations, plans and prospects for Senseonics and its business, including statements regarding managements plans, objectives and goals for future operations, expectations for future financial or other performance, stateme

  3. Slide 3: Our Mission

    OUR MISSION To transform lives in the global diabetes community with differentiated, long-term implantable glucose management technology. 3

  4. Slide 4: Senseonics is targeting the large and growing Type 1 and Type 2 diabetes populations

    Senseonics has the first and only fully-implantable continuous glucose monitor (CGM) that lasts for one year The Eversense ® 365 CGM System was recently cleared by the FDA, with commercial launch now underway Addresses the top complaints with other CGMs including comfort, convenience and accuracy CG

  5. Slide 5: Management

    Management Timothy Goodnow, PhD Mukul Jain, PhD President & Chief Executive Officer Chief Operating Officer Francine Kaufman, M.D. Rick Sullivan Chief Medical Officer Chief Financial Officer 5

  6. Slide 6: High Growth Market

    High Growth Market CGM Fastest Growing Diabetes Technology Segment Globally* Actual Global CGM Market Size ~ 20% CAGR 14 $13.8 12 $20B+ Revenue in Billions ($) $11.6 10 Annual US Total $9.8 8 Addressable Market $8.1 $7.1 Opportunity** 6 $5.5 4 2 0 *Estimates for top 4 CGM companies (Dexcom, Abbott,

  7. Slide 7: Eversense CGM System Addresses Unmet Needs As The First and Only

    Eversense CGM System Addresses Unmet Needs As THE FIRST AND ONLY • CGM that lasts for 12 months vs. 10-15 days • Fully implantable 3rd generation sensor • CGM achieves 8.8% MARD* • Transmitter that is removable • System with on-body vibe alerts for hypo and hyper warnings • System with fresh, gentle

  8. Slide 8: Strong and Expanding Reimbursement

    Strong and Expanding Reimbursement Access For Over 300 Million Lives Broad Commercial and Medicare coverage for both Product and Procedure In April 2025, CMS updated the 2025 physician fee schedule, providing reimbursement for a full year of usage with Eversense 365 retroactive to January 1, 2025 fo

  9. Slide 9: Eversense US Patient Profiles

    Eversense US Patient Profiles1 Capturing New Users and Switching Other CGM Users New Users by Over 3/4 of our US patients switched Diabetes Type from other CGM solutions² 19% New CGM User Type 1 31% Type 2 81% 69% Switched to Eversense 51% Dexcom 43% Libre 5% Medtronic Dissatisfied with Current CGM

  10. Slide 10: Commercial Collaboration with Ascensia

    Commercial Collaboration with ASCENSIA • Broad Partnership Features Global Commercialization and Financing Arrangements with Leader in BGM • ASCENSIA is the Exclusive Worldwide Distribution Partner for Eversense® 365 and next generation product • Senseonics to Focus Streamlined Operations on Manufac

  11. Slide 11: Ascensia Diabetes Care – Senseonics' Commercial Partner

    Ascensia Diabetes Care – Senseonics’ Commercial Partner Four pillars commercial strategy Healthcare Integrations & Direct-to-Consumer Existing Users Professionals Collaborations Comprehensive ~ 50 U.S. dedicated Integration with insulin Maintain focus on Direct to Consumer sales reps calling on pump

  12. Slide 12: A Better Solution for Optimal Patient Care

    A Better Solution for Optimal Patient Care PATIENTS PROVIDERS Empowering Patients to Live a Life Uninterrupted Enabling Confident Clinical Decisions Longest Lasting CGM One CGM. One Year of Minimal Disruptions The only CGM that lasts for a year, while traditional The longest lasting and most dependa

  13. Slide 13: Eversense 365 Commercial Launch

    Eversense 365 Commercial Launch 13

  14. Slide 14: Commercial Growth Driven by Eversense Launch

    Commercial Growth Driven by Eversense 365 Launch Patient installed base increased 56% in 2024, beating target growth of 50% DEMAND CONVERSION 73% 69% Increase in U.S. of new patients are Type Eversense providers 2 users YoY Average Monthly Leads 40% +2X 1/3 81% Increase in of patients switched from

  15. Slide 15: Hospital System Opportunity Overview

    Hospital System Opportunity Overview Market Potential Strategic Goals • Over 1,800 Accountable Care • Enhance quality of care – HEDIS diabetes $413B $413B Organizations • 400 health systems score improvement • Reduce avoidable hospital admissions and Total Cost of Total Cost of emergency visits and

  16. Slide 16: New Strategic Partnership with Sequel Diabetes

    New Strategic Partnership with Sequel Diabetes First Automatic Insulin Delivery Pump Partnership Executed • Commercial development agreement announced in April 2025 • Partnership to enable real-time readings from Eversense® to be received by the twiist pump • Readings used in the Loop algorithm to a

  17. Slide 17: Eversense Projected Patient Ramp

    Eversense Projected Patient Ramp Today > 10M patients utilize CGM 100,000 1.00% 90,000 80,000 0.80% Eversense Patients 70,000 Market Share 60,000 0.60% Projected Break Even 50,000 40,000 0.40% 30,000 20,000 0.20% 10,000 - 0.00% 2023 2024 E 2025 E 2026 E 2027 E Patients Market Share Less than a 1% ma

  18. Slide 18: Product Vision

    PRODUCT VISION Uniquely differentiated long-term technology solution with multiple product configurations with AID and Smart Pen integration SENSOR All Diabetes Patient Segments NO sensor change for 1 year NO daily calibration required NO transmitter on body For Type 1 and Type 2 Patients On Demand

  19. Slide 19: Gemini System

    Gemini System Autonomous Sensor Testing with Data Processing Capacity Enabling 2 Products from 1 Platform Technology Enhanced 365 sensor with integrated battery; updated algorithm Use Case Full year use with 1 sensor and 1 cal/week Two unique products: Standalone CGM with therapeutic FGM transmitter

  20. Slide 20: Freedom System

    Freedom System Elimination Of Transmitter By Incorporating Bluetooth In The Sensor Technology Enhanced 365 sensor with integrated battery and Bluetooth communication; updated algorithm Use Case Full year use with 1 sensor and 1 cal/week No transmitter included in the System Direct communication betw

  21. Slide 21: Portfolio Overview & Potential Catalysts

    Portfolio Overview & Potential Catalysts 2024 2025 2026 2027 2028 Eversense® 365 Approval with CE Approval EU Launch iCGM designation Expected Expected World’s first one-year sensor Gemini One-year sensor with battery Complete Submit IDE Commercial for continuous and optional feasibility trial Launc

  22. Slide 22: Thank You

    Thank You Corporate Overview May 2025 22

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