Eli Lilly And Company · NYSE:LLY

Eli Lilly And — Lilly ELI & — Merger or Acquisition (January 2019)

15 slides from Eli Lilly And's merger presentation, Jan 7, 2019

  1. Slide 1: Exhibit 99.2

    Exhibit 99.2Exhibit 99.2

  2. Slide 2: Agenda

    Agenda Transaction Highlights and Strategic Rationale Dave Ricks, Chairman and Chief Executive Officer Combination with Lilly Oncology Anne White, President, Lilly Oncology Loxo Oncology Portfolio Overview Dan Skovronsky, M.D., Ph.D., Chief Scientific Officer and President, Lilly Research Labs Finan

  3. Slide 3: Safe Harbor Provision

    SAFE HARBOR PROVISION Soa. During this conference call, we anticipate making projections and forward-looking statements that are based ut actual results may differ materially due to various factors. For example: our results — alone or following the completion of this acquisition - may be affected by

  4. Slide 4: Additional Information About the Acquisition and Where to Find It

    ADDITIONAL INFORMATION ABOUT THE ACQUISITION AND WHERE TO FIND IT The tender offer for the outstanding shares of Loxo Oncology referenced in this ication has not yet This communication is for informational purposes only and is neither an offer to purchase nor a solicitation of an offer to sell share

  5. Slide 5: Strategic Rationale

    STRATEGIC RATIONALE Loxo Oncology acquisition consistent with Lilly strategy Grow Revenue + Brings opportunity for multiple near-term launches, bolstering oncology franchise + Enhances growth prospects post-Alimta patent expiration + Contributes revenue in 2019 Create Long-Term Value + Consistent wi

  6. Slide 6: Lilly Oncology Portfolio Enhanced

    LILLY ONCOLOGY PORTFOLIO E Existing Lilly Oncology Pipeline as of January 4, 201 NHANCED 4 Not for promotional use @ chemicatenriy @ siotechenry NiLeX LOKO Additions * commercial Collaboration §

  7. Slide 7: Loxo Oncology Portfolio

    LOXO ONCOLOGY PORTFOLIO Highly selective, targeted cancer therapies for specific tumor mutations EARLY STAGE LATE STAGE REGULATORY PRECLINICAL DEVELOPMENT DEVELOPMENT SUBMISSION APPROVED VITRAKVI® (larotrectinib) - TRK Inhibitor, in collaboration with Bayer LOX0-292-¢. harboring RET-fusions or activ

  8. Slide 8: Vitrakvi (larotrectinib)

    VITRAKVI (LAROTRECTINIB) SELECTIVE ORAL TRK INHIBITOR IN COLLABORATION WITH BAYER") Lit, First in class NEJM publication February 2018 © FDA accelerated approval November 2018 © Clinical data in 55 patients with TRK fusion cancer © Submitted to EMA in August 2018 ITPCC September 2018 . © Poster with

  9. Slide 9: LOXO-195

    LOXO- 95 NEXT GENERATION TRK INHIBITOR IN COLLABORATION WITH BAYER") LL», KEY ATTRIBUTES DATA PRESENTATIONS Continuation of TRK franchise AACR-NCI-EORTC International Conference © Designed to address acquired resistance in patients on Molecular Targets and Cancer treated with TRK inhibitors Therapeu

  10. Slide 10: LOXO-292

    LOXO-292 HIGHLY SELECTIVE ORAL RET INHIBITOR, FULLY OWNED BY LOXO ONCOLOGY Lit, KEY ATTRIBUTES DATA PRESENTATIONS Potentially first-in-class, launching in 2020 ASCO June 2018 © Breakthrough Therapy designation for three | ° 82 patients with RET-altered cancers indications: — RET-fusion positive NSCL

  11. Slide 11: LOXO-305

    LOXO-305 HIGHLY SELECTIVE NON-COVALENT BTK INHIBITOR, FULLY OWNED BY LOXO ONCOLOGY A, ) KEY ATTRIBUTES DATA PRESENTATIONS Designed to address resistance and Society of Hematologic Oncology Annual intolerance in patients treated with Meeting September 2018 approved BTK inhibitors BTKis a validated th

  12. Slide 12: Financial Implications: Offer Summary and Sources of Value

    FINANCIAL IMPLICATIONS OFFER SUMMARY AND SOURCES OF VALUE OFFER SUMMARY All-cash tender at $235.00 per share Premium of approximately 68% to the closing share price on January 4, 2019 Aggregate purchase price of approximately $8.0 billion Net of Loxo Oncology cash and investments, purchase price of

  13. Slide 13: Financial Implications: Financing Summary and Financial Impact

    FINANCIAL IMPLICATIONS FINANCING SUMMARY AND FINANCIAL IMPACT FINANCING SUMMARY FINANCIAL IMPACT Combination of cash and debt to fund No changes to 2020 financial acquisition expectations Maintain flexibility to pursue licensing Impact to 2019 Financial Guidance to be and M&A within current credit r

  14. Slide 14: Summary

    Loxo Oncology is an exciting acquisition for Lilly, continuing our strategy of utilizing external innovation to augment internal research and development efforts Targeted therapies and genetic-based diagnostics offer significant potential to improve the lives of people with S U m m a ry advanced can

  15. Slide 15: Question and Answer Session

    Question and Answer Session

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