Jacobs Solutions Inc. · NYSE:J

Jacobs Solutions — In the kNOW Webinar Series (September 2020)

45 slides from Jacobs Solutions's conference presentation, Sep 21, 2020

  1. Slide 1: Wastewater Epidemiology: Lessons Learned from the COVID-19 Pandemic

    Wastewater Epidemiology: Lessons Learned from the COVID-19 Pandemic In the kNOW Webinar Series Sept. 21, 2020

  2. Slide 2: Agenda

    Agenda  Moderator: Peter Nicol, Jacobs Global Market Director for Water  Tim Constantine, Jacobs Global Technology Leader for Wastewater Treatment will discuss treatment plant testing for COVID-19 in the United States  Scott Harding, Account Manager for COVID-19 Testing and James Herrin, Project

  3. Slide 3: Monitoring COVID-19 Spread in Wastewater Streams

    Monitoring COVID-19 Spread in Wastewater Streams  Our Water, Digital Solutions and OMFS teams launched pilot program to monitor wastewater streams to understand the impacts and spread of COVID-19  Genetic testing techniques, sampling raw wastewater allows for tracking virus in raw wastewater, whic

  4. Slide 4: Wastewater Treatment Plant Testing for COVID-19

    Wastewater Treatment Plant Testing for COVID-19 September 21st, 2020

  5. Slide 5: Background – Wastewater Based Epidemiology (WBE)

    Background – Wastewater Based Epidemiology (WBE) 5 ©Jacobs 2020

  6. Slide 6: Background – Wastewater Based Epidemiology (WBE)

    Background – Wastewater Based Epidemiology (WBE) • WBE studies provide a data driven picture of the virus in communities: – Environmental surveillance – Long-term trends – Early warning system • Non-invasive method for SARS-CoV-2 detection – Detected in waste of asymptomatic people • WBE has been us

  7. Slide 7: Jacobs COVID-19 Initiative Details

    Jacobs COVID-19 Initiative Details • Jacobs operates over 100 Wastewater Treatment facilities worldwide • 70+ facilities in USA • Early April 2020 Jacobs- funded initiative launched to test these facilities for virus in raw sewage My personal motivation: John Gerald Toohey January 21st, 1927 – April

  8. Slide 8: Mobilizing Jacobs COVID-19 Initiative

    Mobilizing Jacobs COVID-19 Initiative • Found academic partner in Arizona State University (ASU) Consent Form Biodesign Institute • Jacobs O&M group facilitated client communication – COVID sampling info Dlyer – Consent form for sampling • Developed sampling plan in coordination with ASU • Original

  9. Slide 9: Mobilizing Jacobs COVID-19 Initiative

    Mobilizing Jacobs COVID-19 Initiative • Found academic partner in Arizona State University (ASU) Consent Form Biodesign Institute • Jacobs O&M group facilitated client communication 18 WWTPs 7 WWTPs – COVID sampling info Dlyer Sampled Sampled – Consent form for sampling • Developed sampling plan in

  10. Slide 10: Test Results (ASU): Non-detects Prevalent

    Test Results (ASU): Non-detects Prevalent • Sampling/shipping issues? • Issues at lab with viral * extraction, detection, quantification? • Is the sewage “matrix” inhibiting testing and by how much? • Degradation of RNA in sewers? Temp effects? ̶ Non-detect Result • Did we miss the ̶ Virus Detected

  11. Slide 11: SARS CoV-2 Testing Results – Facility 8

    SARS CoV-2 Testing Results – “Facility 8” 300 1,500 Viral Concentration [Copies/L x 1,000] Confirmed New Cases per Day in City 250 1,250 ASU Results 200 1,000 150 750 100 500 Source Molecular Results 50 250 11 ©Jacobs 2020

  12. Slide 12: Summary to Date of Jacobs COVID-19 Testing Program

    Summary to Date of Jacobs COVID-19 Testing Program Lessons Learned Next Steps • Logistics of sample collection, shipping & receiving not trivial • Continue with ASU, re-analyze • Virus can be detected, but samples with new lab methods many non-detects early on • Continue successes with Source • Many

  13. Slide 13: COVID-19 Testing Protocols

    COVID-19 Testing Protocols James Herrin, Source Molecular Scott Harding, Source Molecular

  14. Slide 14: Who is Source Molecular?

    Who is Source Molecular? ● Environmental Biological Testing Laboratory (Est. 2002) ● Accredited by A2LA to ISO 17025:2017 ● Background in Microbial Source Tracking (MST) and pathogen detection in environmental samples ● Experienced in extracting RNA and DNA from wastewater samples & analyzing for th

  15. Slide 15: WBE Workflow, From Sample to Decision

    WBE WorkDlow, From Sample to Decision 15

  16. Slide 16: WBE Workflow, From Sample to Decision

    WBE Workflow, From Sample to Decision Analytical Processes 16

  17. Slide 17: WBE Workflow, From Sample to Decision

    WBE Workflow, From Sample to Decision Analytical Processes BSL 1 No Concentration, lower volume Biosafety Level BSL 2 Concentration Method, higher volume 17

  18. Slide 18: WBE Workflow, From Sample to Decision

    WBE Workflow, From Sample to Decision Analytical Processes Envelope QAQC should be adequate to address potential for false positives, false negatives, and contamination Extraction RNA 18

  19. Slide 19: WBE Workflow, From Sample to Decision

    WBE Workflow, From Sample to Decision Analytical Processes 19

  20. Slide 20: SARS-COV-2 Results Report

    SARS-COV-2 Results Report 20

  21. Slide 21: Wastewater Epidemiology Implementation Programs in the Middle East

    Wastewater Epidemiology Implementation Programs in the Middle East Mel Makdessi, Jacobs

  22. Slide 22: WBE Concept

    WBE Concept THE CONCEPT ADVANTAGES  Mapping of spatial trends Examples:  Use rRT – PCR on wastewater • Khalifa University,  Positive or negative for genetic fragments  Mapping of temporal trends Abu Dhabi  Full population coverage successfully  Quantify the magnitude of RNA detected SARS-CoV-

  23. Slide 23: WBE Concept

    WBE Concept !"# $ %&', (&), %'* Transportation Modelling : , , , . , Hydraulic Modelling Data-Processing 23 ©Jacobs 2020

  24. Slide 24: Scalable and Adaptable to Needs

    Scalable and Adaptable to Needs District 2.1.1 Major PS 1 PS 2.1 District 2.1.2 Major WWTP PS 2 PS 2.2 District 3.1.1 Major PS 3 PS 3.1 No Signal Weak Signal District 3.1.2 Strong Signal 24 ©Jacobs 2020

  25. Slide 25: WBE Opportunities & Risks

    WBE Opportunities & Risks OPPORTUNITIES RISKS  HIGH COVERAGE of population  Thousands of samples, DATA INTEGRITY in hands of  SigniDicantly REDUCED COST and resources multiple Civil Contractors, laboratories  FREQUENT testing, quick reporting  To be REPRESENTATIVE, sample locations and timings

  26. Slide 26: Jacobs' Solution

    Jacobs’ Solution QUICK-START PLAN PLANNING  Mobilization  Updating Sampling Plan  Approvals  Send Work Orders to  Procurement Contractors, Laboratories PUBLISH TO LIVE STAKEHOLDER DASHBOARD FIELD SAMPLING FEEDBACK  Supervise Contractors,  Live updates to mobile devices  Map to Health Sector

  27. Slide 27: Summary

    Summary WBE is not a new concept. Full potential not yet realized. Not limited to COVID-19 detection. Scalable, long term potential. Lead Indicator for Health Authorities, Proactive vs Reactive. Addresses the gaps in other current detection methods. Complexity in implementation.

  28. Slide 28: Collection System Sampling

    Collection System Sampling Susan Moisio, Jacobs

  29. Slide 29: Collection System Overview

    Collection System Overview District 2.1.1 Major PS 1 PS 2.1 District 2.1.2 Major WWTP PS 2 PS 2.2 District 3.1.1 Major PS 3 PS 3.1 No Signal Weak Signal District 3.1.2 Strong Signal 29 ©Jacobs 2020

  30. Slide 30: Why move into the collection system and sample?

    Why move into the collection system and sample? Our goal is to locate the area served by Major PS 2.4 and we may not find this area if PS 1 we only sample at the plant PS 2.1 Major PS 2.4 WWTP PS 2 PS 2.2 PS 2.3 PS 2.5 Major PS 3 PS 3.1 No Signal Weak Signal Strong Signal 30 ©Jacobs 2020

  31. Slide 31: Collection System Changes the Dynamics and Introduces More Complexity

    Collection System Changes the Dynamics and Introduces More Complexity Major PS 1 Major  Size of the Collection System WWTP PS 2  Type of Collection System  Configuration of the Collection System Major PS 3 No Signal Weak Signal Strong Signal 31 ©Jacobs 2020

  32. Slide 32: Collection System Size Impacts Sampling – Time of Travel

    Collection System Size Impacts Sampling – Time of Travel Major PS 1 PS 2.1 Major PS 2.4 WWTP PS 2 PS 2.2 PS 2.3 PS 2.5 Major PS 3 PS 3.1 Time of Travel 32 ©Jacobs 2020

  33. Slide 33: Collection System Size Impacts Sampling – Time of Travel

    Collection System Size Impacts Sampling – Time of Travel PS 2.4 Major PS 2.3 PS 1 PS 2.1 PS 2.5 Major PS 2.4 WWTP PS 2 PS 2.2 PS 2.3 PS 2.4 PS 2.4 PS 2.5 PS 2.3 Major PS 3 PS 2.5 PS 2.5 PS 3.1 Time of Travel 33 ©Jacobs 2020

  34. Slide 34: Sanitary Sewer Overflows or Inflow and Infiltration Can Impact the Sample

    Sanitary Sewer Overflows or Inflow and Infiltration Can Impact the Sample Major PS 1 Sanitary Sewer OverDlow - SSO PS 2.1 Major WWTP PS 2 6 PS 2.2 5 4 Major 3 Sanitary Sewer Wet PS 3 Weather Hydrograph 2 PS 3.1 1 0 4/10/2009 12:00 4/14/2009 12:00 34 ©Jacobs 2020

  35. Slide 35: Sampling at Known or Suspected Hotspots

    Sampling at Known or Suspected Hotspots Major PS 1 Known or Suspected Hotspot PS 2.1 Major PS 2.4 WWTP PS 2 PS 2.2 PS 2.3 PS 2.5 Major PS 3 PS 3.1 No Signal Weak Signal Strong Signal 35 ©Jacobs 2020

  36. Slide 36: Structures, Collection System Configuration Impact Sample

    Structures, Collection System ConDiguration Impact Sample  Pretreatment Facilities  Equalization Facilities for Wet Weather either tanks or tunnels  Flow Equalization for Treatment Plant Processes  Pump Station Wet Wells 36 ©Jacobs 2020

  37. Slide 37: Advantages & Disadvantages of Composite or Grab Samples

    Advantages & Disadvantages of Composite or Grab Samples Composite Sampler pulls individual samples over time 37 ©Jacobs 2020 Grab samples can be scheduled

  38. Slide 38: Exploring Technology for COVID-19 Tracking that Capitalizes on Sensors in the Collection System

    Exploring Technology for COVID-19 Tracking that Capitalizes on Sensors in the Collection System Morning Peak of the Diurnal Pattern Using flow data enables us to develop a sampling plan to sample 38 when the virus is most prevalent in the sewer. ©Jacobs 2020

  39. Slide 39: Is the Vaccine Effective?

    Is the Vaccine Effective?  In 2013, researchers in Israel detected an outbreak of polio through their wastewater epidemiology program before any local clinics reported symptoms. Armed with this information, the government targeted vaccination efforts that effectively contained the outbreak.  Sampl

  40. Slide 40: We see an Early Warning System needed

    We see an Early Warning System needed such as we did for Drinking Water for the US EPA 40 ©Jacobs 2020

  41. Slide 41: US EPA Water Security Initiative (WSi)

    US EPA Water Security Initiative (WSi)  Post 9/11, Development of WSi Program − HR 3448 Public Health Security and Bio-terrorism Response Act − HSPD-9 Directed EPA to ...“develop robust, comprehensive, and fully coordinated surveillance and monitoring systems for water quality that provides early d

  42. Slide 42: Insight Through Realtime Data Fusion

    Insight Through Realtime Data Fusion Other System Information Online Water Quality Monitoring Sampling & Analysis Event Detection Developed SRS Architecture Enhanced Security Dashboard Monitoring  Multiple streaming data feeds Customer Complaint  Realtime analytics Surveillance Alert Possible Cred

  43. Slide 43: NYC Water Supply

    NYC Water Supply  Deliver > 1 billion gallons of water daily  To > 9 million customers  19 reservoirs, 3 controlled lakes  > 6,000 miles of pipes, aqueducts, and tunnels  Gravity feed  98% of water from Cat/Del watershed − Not Diltered 43 ©Jacobs 2020

  44. Slide 44: Real-time Dashboard

    CCS Search Date Selected: Thu Oct 1 2009 Total Number of Calls: 4 312 407 V4 Jericho o ol Hitksville Cio7) 28-Westbu 25 Mined) bury iden City, ° East Meadow >, soevinown .

  45. Slide 45: Thank you!

    Thank you! Questions & Answers

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