Simulations Plus, Inc. · NASDAQ:SLP

Simulations Plus — Shareholder Meeting (February 2011)

35 slides from Simulations Plus's shareholder meeting presentation, Feb 23, 2011

  1. Slide 1: Simulations Plus, Inc. Annual Shareholders Meeting

    Exhibit 99.1 Simulations Plus, Inc. Annual Shareholders Meeting February 18, 2011

  2. Slide 2: Agenda

    Agenda • Welcome and Introductions • Discussion of Voting Issues • Chairman’s Remarks • Questions & Answers • Adjournment of Official Meeting

  3. Slide 3: Management & Directors

    Management & Directors • Board of Directors: – Walter S. Woltosz, M.S., M.A.S., Chairman & CEO. • Co-founder, Words+, Inc. and Simulations Plus, Inc. – David Z. D’Argenio, Ph.D., Director • Professor, Biomedical Engineering, USC • Director, Co-Director, Biological Simulation Resource Center, USC sin

  4. Slide 4: Outside Counsels

    Outside Counsels • Registered Independent Auditors • Rose, Snyder & Jacobs, Encino, CA • Tax Specialists • Rabbani, Inc., Los Angeles, CA • Legal Counsel • Luce, Forward, Hamilton & Scripps, San Diego, CA

  5. Slide 5: Discussion of Voting Issues

    Discussion of Voting Issues Candidates for Board of Directors remain unchanged: • David Z. D’Argenio, Ph.D. • Richard R. Weiss, Ph.D. • H. Wayne Rosenberger • Virginia E. Woltosz, MBA • Walter S. Woltosz, MS, MAS • Outside auditor: • Rose, Snyder, Jacobs • Expansion of Board of Directors to minimum

  6. Slide 6: Chairman's Remarks

    Chairman’s Remarks • Company Overview • Financial Performance • Words+, Inc. • Simulations Plus, Inc.

  7. Slide 7: Safe Harbor Statement Under the Private Securities Litigation Act 1995

    Safe Harbor Statement Under the Private Securities Litigation Act 1995 With the exception of historical information, the matters discussed in this presentation are forward looking statements that involve a number of risks and uncertainties. The actual results of the Company could differ significantl

  8. Slide 8: Historical Consolidated Revenue

    Historical Consolidated Revenue 21% 81%

  9. Slide 9: Consolidated Income Statement (3M) FY11.1 vs. FY10.1

    Consolidated Income Statement (3M) FY11.1 vs. FY10.1 +15.3% +22.1% +13.1% +5.9% +20.3% +41.4% +74.0% +24.7% +11.3% +31.9%

  10. Slide 10: Simulations Plus Income Statement (3M) FY11.1 vs. FY10.1

    Simulations Plus Income Statement (3M) FY11.1 vs. FY10.1 +18.2% +22.5% +17.4% +9.8% -16.9% +40.0% -74.7% +23.8% +11.3% +30.3%

  11. Slide 11: Words+ Income Statement (3M) FY11.1 vs. FY10.1

    Words+ Income Statement (3M) FY11.1 vs. FY10.1 +8.3% +21.7% -2.9% -0.5% -63.2% -23.1% +0.0% -25.0%

  12. Slide 12: Market Profile

    Market Profile • Symbol: NASDAQ: SLP • Market Capitalization: $51.91 million* • Recent Price: $3.35* • Average Daily Volume last 3 mo = 42,313*, last 10 days = 72,067* • Shares outstanding: 15.5 million* (9.5% held by institutions)* • Public float: 4.81 million* • 12 Month Price Range: $ 1.62 - 3.74

  13. Slide 13: Share Repurchase Program

    Share Repurchase Program • Board of directors authorized a second share repurchase program for up to one million shares from February 15, 2010 through February 14, 2011 – Purchased 996,248 shares out of authorized 1 MM at average price of $2.8341 including commissions (Total cost of $2,823,795). • J

  14. Slide 14: 12-Month Stock Prices

    12-Month Stock Prices Simulations Pies, Ine Simubalions Plus, inc. . ~ vets ve a eee ee any oor) Hey Le Pen ween cum mn sec abindtil ais. ill aut disidll dics snlaatul alld pais wash bat bi ki Accabatvtal the duce, =<" simulationsplus, inc. oe

  15. Slide 15: Words+ Overview

    Words+ Overview • Words+, Inc. – Global business founded 1981 - pioneer business – Assistive technology products for disabled • Hardware • Software • Support products – Technology leader and innovator since inception – Provides some synergies and overhead cost-sharing with pharmaceutical/biotech bus

  16. Slide 16: Words+ Financial Performance

    Words+ Financial Performance FY 2010 vs FY2009

  17. Slide 17: Factors Affecting Words+ Financials

    Factors Affecting Words+ Financials • Positive • EyePro sales have helped since its introduction last year • New product developments (not yet announced for competitive reasons) • Funding software package has improved accounts receivable collection cycle • Negative – Cost of Sales higher on products

  18. Slide 18: EyePro

    EyePro • Introduced in May 2010 • Contributed to very profitable 4th quarter for Words+

  19. Slide 19: Words+ AR Aging is Improving

    Words+ AR Aging is Improving * * PacWare software started in Oct-09.

  20. Slide 20: Words+ Growth Strategies

    Words+ Growth Strategies • Expand Product Offerings – Focus product development on market needs – Form alliances with other assistive technology companies • Increase product awareness – Workshops, conferences, webinars, web store – Alliances with key clinicians and educators • Increase dealer effect

  21. Slide 21: Simulations Plus (Life Sciences) Overview

    Simulations Plus (Life Sciences) Overview • Simulations Plus, Inc. – Software for pharmaceutical research • Simulation technologies • GastroPlus™ • DDDPlus™ • ADMET Predictor™ • MedChem Studio™

  22. Slide 22: GastroPlus

    GastroPlusTM • The industry’s Gold Standard - most advanced and widely used simulation of oral absorption/pharmacokinetics/pharmacodynamics • Version 7.0 release in August 2010: – Drug-drug Interaction Module released - new extra-cost module – Additional Dosing Routes Module released - new extra-cos

  23. Slide 23: DDDPlus

    DDDPlusTM • First and only simulation tool for in vitro dissolution experiments • Industry is learning how to use this unique tool and sales continue to grow • Strategy going forward: – Continue advancing state-of-the-art for this one-of-a-kind tool – Continue aggressive marketing and sales activiti

  24. Slide 24: ADMET Predictor

    ADMET PredictorTM • Predicts properties of molecules from just their structures, including physicochemical properties, pharmacokinetic properties, metabolism properties, and numerous toxicities • Consistently top-ranked in accuracy in published independent comparison studies • Version 5.0 released i

  25. Slide 25: ADMET Modeler

    ADMET ModelerTM • Integrated with ADMET Predictor - provides complete modeling/prediction capability - used to build all models in ADMET Predictor except for a few simple calculations • Speed and model quality unsurpassed - contract studies have shown ability to find useful models from user data (in

  26. Slide 26: MedChem Studio

    MedChem StudioTM • Formerly ClassPharmer™. renamed it MedChem Studio last year • Classifies molecules by “maximum common substructures” using proprietary algorithms (red parts of molecules above) • Helps chemists identify what it is about molecular structures that cause good or bad properties • Gene

  27. Slide 27: MedChem Designer

    MedChem DesignerTM • Exciting new product launched on February 17, 2011! Provided free • Exciting combination of innovative molecule drawing capabilities that integrates tightly with ADMET Predictor • Provides chemist with never-before-available information about how each change to a molecule affect

  28. Slide 28: Consulting Contracts

    Consulting Contracts • Growing part of business – Simulation studies • Troubleshooting problem compounds • Virtual bioequivalence trials • Assist with design of new oral dosage formulations • Generates leads for software licenses • Identifies unmet needs for software improvements • Increases our kno

  29. Slide 29: Some of Our International Pharma Customers

    Some of Our International Pharma Customers

  30. Slide 30: Core Capabilities and Strengths

    Core Capabilities and Strengths – Growing team of exceptional scientists and engineers • Chemistry, biochemistry, molecular biology • Chemical engineering, biomedical engineering • Computer science • Augmentative communication (Words+ subsidiary) – Recognized world-class expertise in oral drug deliv

  31. Slide 31: Strategic Considerations

    Strategic Considerations • Aggressive marketing and sales activities have paid off, and will continue • Development of new technologies via in-house funding – Continue to develop new products such as our new MedChem Designer™ software announced yesterday – Maintain our industry-leading position with

  32. Slide 32: Investment Highlights

    Investment Highlights • World-class and growing scientific team • Experienced professional management team and board • Continuously growing and profitable through global economic crisis • High margins: earnings growth > revenues growth • Approximately $8.9 MM in cash and no debt • Emerging, high-gro

  33. Slide 33: Simulations Plus, Inc.

    Simulations Plus, Inc. Increasing shareholder value by providing competitive advantages to our customers in the pharmaceutical, biotech, and disability industries

  34. Slide 34: Questions and Answers

    Questions and Answers Opportunity for shareholders to ask questions about the company. Please understand that we cannot provide any information that would be considered “insider information” - information that would provide those attending this meeting with knowledge about company operations that wo

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