Altria Group, Inc. · NYSE:MO
Altria — Global Forum on Nicotine 2018
11 slides from Altria's conference presentation, Jun 15, 2018
Slide 1: The Harm Reduction Opportunity with Smokeless Tobacco Products
The Harm Reduction Opportunity with Smokeless Tobacco Products Global Forum on Nicotine – Keynote Speech June 15th 2018 Mohamadi Sarkar M. Pharm, Ph.D., FCCP Fellow, Scientific Strategy and Analysis Altria Client Services Altria Client Services l Regulatory Affairs l Global Forum on Nicotine l 6/15/
Slide 2: Cigarette Smoking: A Significant Public Health Problem
Cigarette Smoking: A Significant Public Health Problem Cigarette smoking Cigarette smoking Smokers’ life causes about causes an expectancy one of every estimated 480,000 is about five deaths annually deaths annually 10 years shorter in the U.S. than nonsmokers’ Source: http://www.cdc.gov/tobacco/dat
Slide 3: Harm Reduction Opportunities
Harm Reduction Opportunities ~5 MM Adult Smokeless Consumers ~40 MM Adult Cigarette Smokers ~10 MM Adult E-Vapor Consumers Note: Figures shown are U.S Adult Tobacco Consumers Source: 18+ATCT 12MM ending December 2017 Numbers may not foot due to rounding Altria Client Services l Regulatory Affairs l
Slide 4: Over Half of U.S. Adult Smokers Are Interested in Reduced-Risk Tobacco Products
Over Half of U.S. Adult Smokers Are Interested in Reduced-Risk Tobacco Products Source: Based on ALCS analysis of PATH Wave 1 data Sept 12, 2013 – Dec 14, 2014; Response to question – “If a tobacco product made a claim that it was less harmful to health than other tobacco products, how likely would
Slide 5: Innovative Non-Combustible Product Platforms
Innovative Non-Combustible Product Platforms Smokeless/Oral Tobacco‐Derived Nicotine E‐Vapor Heated Tobacco Altria Client Services l Regulatory Affairs l Global Forum on Nicotine l 6/15/2018 l FINAL | 5
Slide 6: Misperceptions about the Risks of Smokeless Tobacco vs. Cigarettes
Misperceptions about the Risks of Smokeless Tobacco (ST) vs. Cigarettes Over 90% of cigarette smokers think ST* is about the same or more harmful than cigarettes % of adult cigarette smokers thinking each product % of adult cigarette smokers thinking each product is about the same harm as cigarettes
Slide 7: USSTC Submits MRTP Application (MRTPA)
USSTC Submits MRTP Application (MRTPA) MRTPA Submitted 3/20/18 365 Day Review Period from FDA filing Tobacco Products Scientific Advisory Committee (TPSAC) meeting Altria Client Services l Regulatory Affairs l Global Forum on Nicotine l 6/15/2018 l FINAL | 7
Slide 8: Linked Mortality Analysis: Based on Nationally Representative Epidemiology
Linked Mortality Analysis: Based on Nationally Representative Epidemiology National Health Interview Survey National Longitudinal Mortality Study Survey Years: 1987 – 2005 (intermittent) Based on the Current Population Survey ~155,000 total respondents Survey years: 1993-2005 • ~3,000 smokel
Slide 9: Major Causes of Mortality
Major Causes of Mortality Mortality Current Current outcome Cigarette Smokers Smokeless Tobacco Users NEVER USED NEVER USED TOBACCO TOBACCO All causes Diseases of the heart Malignant neoplasms 0 1 2 3 4 0 1 2 3 4 HAZARD RATIO HAZARD RATIO NHIS (N=36,090) NLMS (N=38,076) NHIS (N=1,562) NLMS (N=1,863)
Slide 10: Specific Cancer Mortality
Specific Cancer Mortality Mortality Current Smokers vs. Never Smokers Current ST Users vs. Never ST Users outcome Esophagus1 NR <5 Deaths2 Pancreas Oral cavity, lip and pharynx1 NR <5 Deaths2 Trachea, bronchus 11.52 and lung 0 1 2 3 4 5 6 7 8 9 10 0 1 2 3 4 5 6 7 8 9 10 HAZARD RATIO Current cigarett
Slide 11: Summary
Summary Significant misperceptions exist regarding ST products among U.S. Adult Smokers despite the substantial risk differential Completely switching from cigarettes to ST presents a harm reduction opportunity Our MRTP application on Copenhagen® Fine Cut has the potential to: - Correct widely