Endra Life Sciences Inc. · NASDAQ:NDRA
Endra Life Sciences — Investor Presentation (September 2020)
16 slides from Endra Life Sciences's investor presentation, Sep 2, 2020
Slide 1: Addressing the Need in Liver Disease (NAFLD-NASH) Assessment
Addressing the Need in Liver Disease (NAFLD-NASH) Assessment INVESTOR PRESENTATION SEPTEMBER 2020 ENDRA LIFE SCIENCES ‘NASDAQ: NORA
Slide 2: Safe Harbor
Safe Harbor Cras tates ale i resetaten alr eg seme Herat her th sures hte nadir ng snes rear ten how ea al cr satay Mareen tra pestn tre rere propel cat preps. ps obec el maar afer pov aware tenes fernrd key tment grb are eects reat hares Yue rary tet al eaten by eile th "prams" "peepee" ‘esiete” "r
Slide 3: ENDRA Life Sciences Snapshot
ENDRA Life Sciences Snapshot GOAL: VISUALIZE HUMAN TISSUE LIKE MRI ... AT SOX LOWER COST! & POINT OF PATIENT CARE © © ~Wemployees Fla application: Liver Leadership advisors, 6 Plug-and-play maging platform disease (NAFLO-KASH) affecting | Based in Ann Arbor. Michigan. partners from GE with 18 bilion
Slide 4: Focused on a Large and Rapidly Growing Market: NAFLD-NASH
Focused on a Large and Rapidly Growing Market: NAFLD-NASH TOTAL ANNUAL DIRECT MEDICAL COSTS IN U.S. FOR NAFLD: ~$103B? Liver Disease: NAFLD-NASH Diagnastic Gap f* Therapies Near Ibillion+ people affected? Linked to obesity, Current diagnastc tons nat practical Advent of first targeted therapies for
Slide 5: Measuring Liver Fat in NAFLD-NASH Patients
Measuring Liver Fat in NAFLD-NASH Patients CURRENTLY NO PRACTICAL & RIGOROUS TOOL FOR STAGING STEATOSIS OPTIMAL BALANCE x DIAGNOSTIC VALUE 2 Low Low ACCESSIBILITY HIGH (Denona (AFFORDABILITY, SAFETY, EASE OF USE) signe: 3s
Slide 6: Total Addressable Market for NAFLD-NASH Fat Measurement Tool
Total Addressable Market for NAFLD-NASH Fat Measurement Tool $1 BILLION OPPORTUNITY ... WITH UPSIDE Estimated 2019 Number of Facilities’ Facilities (hospitals. clinics, private practices) currently doing 20,000 Performing Abdominal-Liver Ultrasound Scans :~-* —_abdo-liver ultrasound scans, who could
Slide 7: Solution: Thermo Acoustic Enhanced UltraSound (TAEUS)
Solution: Thermo Acoustic Enhanced UltraSound (TAEUS*) RF SIGNALS QUANTITATE LIVER FAT FRACTION ‘Secured 80 19485 Certification Y Completed first human feasibility study (N=I9) + Sensitivity 188 Specificity 182 AUROC 0. MRL-POFF 6% steatosis Dbtained CE Mark: European regulatory approval Y Protected
Slide 8: TAEUS Platform Evolution
TAEUS’ Platform Evolution: MULTIPLE POTENTIAL CLINICAL APPLICATIONS & REVENUE STREAMS TO SCALE BUSINESS HARDWARE SOFTWARE DISPOSABLES LICENSING isc rng ety MISS lle syle ptsoehnce TIS win fee OO . MS acer lcesng TS perme a, rid pes) tegued sens pris Se ‘yea red ‘VASCULAR FLOW - Future S18 bilont TAE
Slide 9: ENDRA 2020 Milestones: Liver Application
ENDRA 2020 Milestones: Liver Application SECURE REGULATORY APPROVALS AND INSTALL FIRST COMMERCIAL SYSTEMS, {H'20 2420 Y Obtain CE Mark certification Announce atonal EU 6 US evaluation sites Y id hepatology influence to ENORA clinical advisory Execute controlled launch in EU with early adopters & sma
Slide 10: ENDRA Partners
ENDRA Partners SUPPORTING TECHNICAL, CLINICAL & COMMERCIAL DEVELOPMENT OF TAEUS @ GE Healthcare Strategic partnership + Supports product development & introductions to GE ultrasound customers: * BE option fort year sales exclusivity on TAEUS liver application and other rights (DENRA Clinical evaluat
Slide 11: Commercialization: Targeting High Value Clinical Segments
Commercializati : Targeting High Value Clinical Segments BUILD AWARENESS AND CLINICAL EVIDENCE & DEPLOY LOCAL TACTICS IMAGING EXPERTS __LIVEREXPERTS METABOLISM & ENDRA COMMERCIAL APPROACH jology __ Gastro-Hepatology LIFESTYLE EXPERTS be) ENORA @ key Clinical sono aa Virtual booths, onlin IE : : 0 pr
Slide 12: Leadership
Leadership MANAGEMENT Francois Michelon Michael Thornton ‘harman 8080 cia I yersiameb tech (Syersmedtoc Eteaticare Smith Nepten, fader heed Bonet Visnstens old 068) INDEPENDENT DIRECTORS Sam Gambhir, MD, PhD Michael Harsh fod SCIENTIFIC ADVISORS (Deno el Teh Or Ret) BE ears Jing Gao, MO Weil Corel M
Slide 13: ENDRA Investment Highlights
ENDRA Investment Highlights Addressing clear unmet need inlver disease (NAFLDAASH), KEY STATISTICS (as of tugs 282020) Hering eae Cash Balance 40M Aged with advent of fst targeted NAFLO-NASH therapies ecindemayane Common Stock rice (NASOAD NORA) 3082 ies Common Shares Outstanding AM Blu-chp commerci
Slide 14: ENDRA
ENDRA
Slide 15: Liver Fat Measurement Tools: Relative Performance & Accessibility
Liver Fat Measurement Tools: Relative Performance & Accessibility ‘i é - eT are ce er parecer) 1 See trad dome eo Sn rer ae Napanee ge a ew cy ae 1 Nite fad pen a BL emieneny + Settee i Femtroncon amine eh + ay ede ae Co ry - $s Nirman 2 0 octet re de anette neat cit natn + int pore Cr + Pa srrerena
Slide 16: Sources & Assumptions
Sources & Assumptions | XN rene preteen pe 1 lew mre ee ry pe a ne ‘ent aha Sr nag th om nye Somer btittre 1 heey Danone rl ney edema ew a ‘te won i Bren 8 (Phat ln po i PAGES 1 ps enn es rd dey rd hep "eu 2 eer re yt i Pc Oh ep pe tin bo ‘teppei ose Ear ee Fae sovpisnrnenereen itera ior ery ow or a
ENDRA Life Sciences — Investor Presentation (September 2020) on 6ix