Arterra Bioscience Spa · MIL:ARBS
Arterra Bioscience Spa — Investor Conference Naples, Banca Profilo 2024
31 slides from Arterra Bioscience Spa's conference presentation, Jun 27, 2024
Slide 1: Investor Conference Naples Banca Profilo
Investor Conference Naples Banca Profilo June 27th, 2024
Slide 2: Index
Index TOPICS • ARTERRA AT GLANCE • MARKET CONSOLIDATION & DIVERSIFICATION • FINANCIALS
Slide 3: People Speaking Today
People Speaking Today M. GABRIELLA COLUCCI GUALTIERO IOIMO Founder, President and CEO CFO and Investor Relations Manager
Slide 4: Arterra Bioscience - Innovative SME
Arterra Bioscience - Innovative SME Arterra Bioscience Is a biotech company listed on the “Euronext Growth Milan” market of Borsa Italiana since 2019, founded in Naples by M. Gabriella Colucci in 2004 with the aim of developing technologies and innovative solutions that find application in various i
Slide 5: Arterra Organization
ARTERRA ORGANIZATION Investor Conference Naples, Banca Profilo June 27th, 2024
Slide 6: Arterra & Vitalab Team
Arterra & Vitalab Team 31 12 PhD 13 Chem Ing 1 MSc 11 Tech 15 PhD Student 3 2000 Sqm
Slide 7: Our facilities
Our facilities Chemistry Lab Plant Cell Culture Lab Microbiology Lab Molecular & Cell Biol Lab Histology & Microscopy Lab Production Lab
Slide 8: Scientific Management team
Scientific Management team M. GABRIELLA COLUCCI GIUSEPPE FERRANTE ANNALISA TITO CEO COO Cell & Mol Biol. Director VINCENZO FOGLIANO MARIDA BIMONTE MAURA ANGELILLO CSO Grant & IP Marketing & Sales Director Manager
Slide 9: Company organization
roc _ Company organization President & CEO Gabriella Colucci Executive Assistant Alexandra Fellermeier Director MANAGEME| QOOROOE IT TEAM (MT) Grant & IP Office Marida Bimonte MID MANAGEMENT TEAM (MMT) ©0008 & @©©CCOOC0O a”. To os A ArterraBioscience
Slide 10: Certifications
roc _ Certifications Va EFFCI up CERTIFIED 2023 ecovadis {Sustainability Rating Azienda certificata da ClimatePartner climate-id.com/RUPASF / A ArterraBioscience
Slide 11: Arterra position in relevant markets
Arterra position in relevant markets Consumer cosmetics Beauty Cosmetics Skin Care, Make-Up, Personal Cair & Professional Cosmetic Products for topical Hair Care applications in Aestetic Medicine consolidated market through Intercos & New segment of a known market Vitalab. Medical Device for topical
Slide 12: Innovation in COSMETICS
Innovation in COSMETICS CONSOLIDATED SEGMENT: SKIN CARE & MAKE-UP & HAIRCARE 2023/2024 Tortora A, et All. Jasminum Sambac as natural antioxidant booster against skin aging. International Journal of Cosmetic Science, 45: 1-61 (2023). Tito A, et All. Oenothera biennis cell culture produce lignans acti
Slide 13: Innovation in COSMETICS: New products on the market
Innovation in COSMETICS 7 New products on the market Vita Gly-Jasmine Cordys Revitagen Vita D-Light Vita RisePeptides Jasminum Sambac Cordyceps sinensis Corthellus shiitake Hydrolyzed Rice Bran Plant cell extract extract extract Extract Vita PeptiBloom Vita NiaCeraMine PlantExo Vita Peonia suffructi
Slide 14: Regulatory Achievements
Regulatory Achievements China State Council released the final version of CSAR on 01 January 2021 and replaced the existing Cosmetics Hygiene Supervision Regulations China’s new cosmetics regulation include many changes: New cosmetic definitions, scope and classifications Management of new cosmetic
Slide 15: Innovation in COSMETICS started in 2023
Innovation in COSMETICS started in 2023 Powder active ingredients for make- up application On the market in Recombinant peptides using molecular 2024 farming technology* Post-Biotics using precision fermentation Technology On the market in 2025 Extracellular Vescicles EV Delivery Systems* In Progres
Slide 16: Powder active ingredients for make-up
Powder active ingredients for make-up Regulatory documentation in preparation. | September 2024 ready for the market. On the market in Loading of MICA with Active 2024 Ingredients AQP3 COL1 Consumer cosmetics
Slide 17: Molecular Pharming Technology: Vegan Collagen
Molecular Pharming Technology: Vegan Collagen On the market in 2024 • Obtained INCI hColl Fragm. FLIFSLLLSLSSAGMKGHRGFSGLGENGLPGERGGFPGAVGGPPGERGGPGARGQAGVMGFPKQDNTIGNGM FSGLGENGLPGERGGFPGAVGGPPGERGGPGARGQAGVMGFPKQDNTIGNGMKGHRGFSGLGENGLPGERGG • Regulatory documentation in GGPPGERGGPGARGQAGVMGFPKQDNT
Slide 18: Precision Fermentation Technology
Precision Fermentation Technology 3 NEW PROPRIETARY STRAINS Lactobacillus fermentum: LfABS1 Lactobacillus fermentum: LfABS2 Lactobacillus paracasei: LcABS3 PATENT ON GENETIC ELEMENTS for Recombinant Proteins, Peptides and dsRNA in Lattobacillus Sp. FERMENTED ACTIVE BOOSTED PRECISION METABOLIC INGRED
Slide 19: Precision Fermentation Technology On the market in 2025
Precision Fermentation Technology On the market in 2025 PRECISION FERMENTATION METABOLIC ENGINEERING Control "We believe that by bridging science and nature, we are well-positioned to thrive in this competitive cosmetic market. Carotenoids Recombinant molecules production Violacein GDF11 – READY FOR
Slide 20: Exosomes: The new wave Opportunity
EXOSOMES: The new wave «Opportunity» Source: Graça Raposo, Willem Stoorvogel, JCB Feb 18,2013 On the market in 2025 Exosomes and EVs are extracellular vesicles released by all cells (eukaryotic or prokaryotic) having a number of complex biological funtions. o They are surrounded by a lipidic membran
Slide 21: Plant exosomes: Claimed properties
Plant exosomes: Claimed properties Source: D. Subha, K. Harshnii, K.G. Madhikiruba, M. Nandhini, K.S. Tamilselvi: Plant derived exosome-like Nanovesicles: an updated overview. Plant Nano Biology 3 (2023) 100022. https://doi.org/10.1016/j.plana.2022.100022
Slide 22: Exosomes in professional beauty treatments today
Exosomes in professional beauty treatments today Source: Zhang B, Gong J, He L, Khan A, Xiong T, Shen H and Li Z (2022). Exosomes based advancements for application in medical aesthetics. Front. Bioeng. Biotechnol. 10:1083640. doi: 10.3389/fbioe.2022.1083640
Slide 23: Global Medicinal Aesthetics Market
Global Medicinal Aesthetics Market
Slide 24: Global Market for Exosomes in skin care
Global Market for Exosomes in skin care probably largely underestimated
Slide 25: Plant exosome production process
ioneering the tracellular e icle ield Preclearing & Ultrafiltration Plant source Lyophilization NTA and Functional Centrifugation & Concentration Nano Analyzers assays ioneering the tracellular e icle ield
Slide 26: Supplement for pathology related disorders
Supplement for pathology related disorders MEDICAL DEVICE & NUTRACEUTICAL ACNE CONTROL COMMERCIALIZED BY ATOPIC DERMATITIS 102021000020309.Estratti derivati da olive e CLINICAL STUDY pale di fico d’India per l’uso nella prevenzione IN PROGRESS e nel trattamento della dermatite atopica. Under evaluat
Slide 27: FINANCIALS
FINANCIALS Investor Conference Naples, Banca Profilo June 27th, 2024
Slide 28: Economic results as of December 31, 2023
32,15% Economic results as of December 31, 2023 Value of Production (€/000) Ebitda (€/000) Net Income (€/000) 26,7% 5.303 40,2% 4951 2500 4.608 37,7% 1.414 498 2133 24,1% 231 21,7% 32,2% 2000 917 1.242 1.111 1.416 1735 1591 1.076 1500 1000 3.825 3.564 3.304 500 -134 0 2021 2022 2023 2021 2022 2023 2
Slide 29: Net Debt / Equity
Net Debt / Equity Net Debt (€/000) Equity (€/000) 10.751 2021 2022 2023 10.467 Cash and Cash Equivalents (4.814) (4.393) (3686) Current Financial 9.473 Receivables - - - 891 Financial assets other 1.823 than fixed assets (1.598) (1.671) Current Financial Debt 223 174 86 Current Net Debt (4.591) (5.8
Slide 30: Difference between first quarter 2024 and first quarter 2023
Difference between first quarter 2024 and first quarter 2023 1Q 2024-1Q 2023 €1.200,00 €1.089,83 The total turnover is increased of 26 %. €1.000,00 +26% €934,00 €862,87 The main difference between first quarter +32% €800,00 2024 and first quarter 2023 is about the €709,00 sale of raw materials, the
Slide 31: THANK YOU!
Investor Conference Naples Banca Profilo THANK YOU!
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